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Cerebral Blood Flow in Patients with Intracranial Pressure Elevation due to Traumatic Brain Edema

Published online by Cambridge University Press:  18 September 2015

W. A. Tweed*
Affiliation:
Department of Anesthesia, Health Sciences Centre (General), Winnipeg, Canada and Odense University Hospital, DK 5000, Odense, Denmark
Jørn Overgaard
Affiliation:
Department of Anesthesia, Health Sciences Centre (General), Winnipeg, Canada and Odense University Hospital, DK 5000, Odense, Denmark
*
Department of Anaesthesia, Health Science Centre, National Institutes of Health, 700 William Ave., Canada, R3E 0Z3
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Summary:

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The object of this study was to determine if traumatic brain edema (BE) and increased intracranial pressure (ICP) reduce cerebral blood flow (CBF). Two groups of patients were studied, one with slight BE and ICP less than 20 mm Hg., the other with pronounced BE and ICP over 20 mm Hg. Although ICP was higher and cerebral perfusion pressure lower in pro-nounced edema there was only a small and non-significant reduction in CBF and no difference in cerebro-vascular resistance. Since traumatic BE does not increase resistance to blood flow through the brain, cerebral perfusion can be maintained if an adequate perfusion pressure is established. This in turn, demands the monitoring and control of ICP.

Type
Research Article
Copyright
Copyright © Canadian Neurological Sciences Federation 1976

References

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