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Cardiac Pharmacology and Cardiomyopathy in Friedreich's Ataxia

Published online by Cambridge University Press:  18 September 2015

Ryan J. Huxtable
Ryan J. Huxtable*
Affiliation:
Department of Pharmacology, University of Arizona Health Sciences Center, Tucson, Arizona
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Friedreich's ataxia is almost always associated with a cardiomyopathy. The cardiomyopathy and its attendant cardiopulmonary sequelae is the usual cause of death in this disease. The author reviews the known pharmacology of the heart, particularly as it applies to hypertrophic cardiomyopathy. The important role played by calcium and the possible role of taurine is stressed. Therapeutic possibilities are mentioned.

Type
Quebec Cooperative Study of Friedreich's Ataxia
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 1 , February 1978 , pp. 83 - 91
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

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