Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-22T18:56:19.018Z Has data issue: false hasContentIssue false

Myth: Parenteral ketorolac provides more effective analgesia than oral ibuprofen

Published online by Cambridge University Press:  21 May 2015

Sanjay Arora*
Affiliation:
Emergency Medicine, Keck School of Medicine, Los Angeles County + University of Southern California (LAC+USC) Department of Emergency Medicine, Los Angeles, Calif.
Jonathan G. Wagner
Affiliation:
Keck School of Medicine, LAC+USC Department of Emergency Medicine, Los Angeles, Calif.
Mel Herbert
Affiliation:
Keck School of Medicine, LAC+USC Department of Emergency Medicine, Los Angeles, Calif.
*
Department of Emergency Medicine, Los Angeles County–USC Healthcare Network, 1200 N State St., Los Angeles CA 90033

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Education • Éducation
Copyright
Copyright © Canadian Association of Emergency Physicians 2007

References

1.Buckley, MM, Brogden, RN.Ketorolac: a review of its pharmacodynamic and pharmacokenetic properties, and therapeutic potential. Drugs 1990;39:86109.CrossRefGoogle Scholar
2.Wright, JM, Price, SD, Watson, WA.NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac. Ann Pharmacother 1994;28:309–12.CrossRefGoogle ScholarPubMed
3.Turturro, MA, Paris, PM, Seaberg, DC.Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. Ann Emerg Med 1995;26:117–20.CrossRefGoogle ScholarPubMed
4.Neighbor, ML, Puntillo, KA.Intramuscular ketorolac vs. oral ibuprofen in emergency department patients with acute pain. Acad Emerg Med 1998;5:118–22.Google Scholar
5.Mixter, CG 3rd, Meeker, LD, Gavin, TJ.Preemptive pain control in patients having laparoscopic hernia repair: a comparison of ketorolac and ibuprofen. Arch Surg 1998;133:432–7.Google Scholar
6.Morrison, NA, Repka, MX.Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. Ophthalmology 1994;101:915–8.Google Scholar
7.Price, DD, Hu, JW, Dubner, R, et al. Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses. Pain 1977;3:5768.Google Scholar
8.Arendt-Neilson, L, Brennum, J, Sindrup, S, et al. Electrophysical and psychophysical quantification of temporal summation in the human nociceptive system. Eur J Appl Physiol 1994;68:266–73.CrossRefGoogle Scholar
9.Guirimand, F, Dupont, X, Brasseur, L, et al. The effects of ketamine on the temporal summation (wind-up) of the R(III) nociceptive flexion reflex and pain in humans. Anesth Analg 2000;90:408–14.CrossRefGoogle Scholar
10.Larsen, LS, Miller, A, Allegra, JR.The use of intravenous ketoro-lac for the treatment of renal colic in the emergency department. Am J Emerg Med 1993;11:197–9.Google Scholar
11.Sandhu, DPS, Iacovou, JW, Fletcher, MS, et al. A comparison of intramuscular ketorolac and pethidine in the alleviation of renal colic. Br J Urol 1994;74:690–3.CrossRefGoogle ScholarPubMed
12.Cordell, WH, Wright, SW, Wolfson, AB, et al. Comparison of intravenous ketorolac, meperidine, and both (balanced analgesia) for renal colic. Ann Emerg Med 1996;28:151–8.CrossRefGoogle ScholarPubMed
13.Oosterlinck, W, Philp, NH, Charig, C, et al. A double-blind single dose comparison of intramuscular ketorolac tromethamine and pethidine in the treatment of renal colic. J Clin Pharmacol 1990;30:336–41.CrossRefGoogle ScholarPubMed
14.Larkin, GL, Peacock, WF IV, Pearl, SM, et al. Efficacy of ketoro-lac tromethamine versus meperidine in the ED treatment of acute renal colic. Am J Emerg Med 1999;17:610.CrossRefGoogle ScholarPubMed
15.Cohen, E, Hafner, R, Rotenberg, Z, et al. Comparison of ketorolac and diclofenac in the treatment of renal colic. Eur J Clin Pharmacol 1998;54:455–8.Google Scholar
16.Stein, A, Ben Dov, D, Finkel, B, et al. Single-dose intramuscular ketorolac versus diclofenac for pain management in renal colic. Am J Emerg Med 1996;14:385–7.Google Scholar
17.Safdar, B, Degutis, LC, Landry, K, et al. Intravenous morphine plus ketorolac is superior to either drug alone for treatment of acute renal colic. Ann Emerg Med 2006;48:173–81.Google Scholar
18.Schwartz, NA, Turturro, MA, Istvan, DJ, et al. Patients’ perceptions of route of nonsteriodal anti-inflammatory drug administration and its effect on analgesia. Acad Emerg Med 2000;7:857–61.Google Scholar