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Extracorporeal membrane oxygenation after protracted ventricular fibrillation cardiac arrest: case report and discussion

Published online by Cambridge University Press:  01 April 2015

Riyad B. Abu-Laban*
Affiliation:
Department of Emergency Medicine, University of British Columbia, Vancouver, BC
David Migneault
Affiliation:
Department of Emergency Medicine, University of British Columbia, Vancouver, BC
Meghan R. Grant
Affiliation:
Department of Emergency Medicine, University of British Columbia, Vancouver, BC
Vinay Dhingra
Affiliation:
Division of Critical Care Medicine, University of British Columbia, Vancouver, BC
Anthony Fung
Affiliation:
Division of Cardiology, University of British Columbia, Vancouver, BC
Richard C. Cook
Affiliation:
Division of Cardiac Surgery, University of British Columbia, Vancouver, BC
David Sweet
Affiliation:
Department of Emergency Medicine, University of British Columbia, Vancouver, BC Division of Critical Care Medicine, University of British Columbia, Vancouver, BC
*
Correspondence to: Dr. Riyad B. Abu-Laban, Department of Emergency Medicine, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC V5Z 1M9; [email protected].

Abstract

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Extracorporeal membrane oxygenation (ECMO) is a method to provide temporary cardiac and respiratory support to critically ill patients. In recent years, the role of ECMO in emergency departments (EDs) for select adults has increased. We present the dramatic case of a 29-year-old man who was placed on venoarterial ECMO for cardiogenic shock and respiratory failure following collapse and protracted ventricular fibrillation cardiac arrest in our ED. Resuscitation efforts prior to ECMO commencement included 49 minutes of virtually continuous cardiopulmonary resuscitation (CPR), 11 defibrillations, administration of numerous medications, including a thrombolytic agent, while CPR was ongoing, percutaneous coronary intervention and stenting for a mid–left anterior descending coronary artery dissection and thrombotic occlusion, inotropic support, and intra-aortic balloon pump counterpulsation. Over the next 48 hours following ECMO commencement, the patient’s cardiorespiratory function rapidly improved, and he was discharged home 9 days after admission with no neurologic sequelae. The history, indications, and increasing role of ECMO in a range of conditions, including cardiac arrest, are reviewed.

Résumé

L’oxygénation extracorporelle sur oxygénateur à membrane (OEOM) est un moyen de fournir une assistance cardiaque et respiratoire temporaire à des patients gravement malades. Le rôle de l’OEOM a gagné du terrain chez certains adultes aux services des urgences (SU) au cours des dernières années. Sera exposé ici le cas spectaculaire d’un homme de 29 ans, soumis à l’OEOM veino-artérielle pour un choc cardiogénique et une insuffisance respiratoire suivant un collapsus et un arrêt cardiaque causé par un accès prolongé de fibrillation ventriculaire, qui est survenu au SU de l’hôpital. Les moyens de réanimation mis en oeuvre avant le début de l’OEOM comprenaient des manoeuvres de réanimation cardiorespiratoire (RCR) pratiquées de façon quasi continue durant 49 minutes; 11 tentatives de défibrillation; l’administration de nombreux médicaments, dont un thrombolytique, pendant que se poursuivaient les manoeuvres de RCR; une intervention coronarienne percutanée et la pose d’une endoprothèse pour une dissection du segment moyen de l’artère interventriculaire antérieure et une oblité ration thrombotique; un soutien inotrope et la contrepulsion par ballon intra-aortique. Au cours des 48 heures suivant le dé but de l’OEOM, l’état cardiorespiratoire du patient s’est amélioré rapidement, et celui-ci est retourné chez lui 9 jours après son admission, et ce, sans souffrir de séquelles neurologiques. Seront passés en revue l’historique, les indications et le rôle de plus en plus grand de l’OEOM dans diverses affections, dont l’arrêt cardiaque.

Type
Case Report
Copyright
Copyright © Canadian Association of Emergency Physicians 2015 

References

1. Mattox, KL, Beall, AC. Resuscitation of the moribund patient using portable cardiopulmonary bypass. Ann Thorac Surg 1976;22:436442, doi:10.1016/S0003-4975(10)64452-9.CrossRefGoogle ScholarPubMed
2. Clark, K, Abu-Laban, RB, Zed, PJ, et al. Neurologically normal survival after fibrinolysis during prolonged cardiac arrest: case report and discussion. CJEM 2003;5:4953.CrossRefGoogle Scholar
3. Abu-Laban, RB, Christenson, JM, Innes, GD, et al. Tissue plasminogen activator in cardiac arrest with pulseless electrical activity. N Engl J Med 2002;346:15221528, doi:10.1056/NEJMoa012885.CrossRefGoogle ScholarPubMed
4. Böttiger, BW, Arntz, H-R, Chamberlain, DA, et al. Thrombolysis during resuscitation for out-of-hospital cardiac arrest. N Engl J Med 2008;359:26512662, doi:10.1056/NEJMoa070570.CrossRefGoogle ScholarPubMed
5. Brodie, D, Bacchetta, M. Extracorporeal membrane oxygenation for ARDS in adults. N Engl J Med 2011;365:19051914, doi:10.1056/NEJMct1103720.CrossRefGoogle ScholarPubMed
6. Chiu, C-C, Chiu, C-W, Chen, Y-C, et al. Cardiac arrest with refractory ventricular fibrillation: a successful resuscitation using extracorporeal membrane oxygenation. Am J Emerg Med 2013;31(264):e12.Google ScholarPubMed
7. Yamamoto, LG, Young, LL. Acute-onset dysrhythmia heralding fulminant myocarditis and refractory cardiac arrest treated with ED cardiopulmonary bypass and extracorporeal membrane oxygenation. Am J Emerg Med 2007;25:348352, doi:10.1016/j.ajem.2006.05.028.CrossRefGoogle ScholarPubMed
8. Posner, JC, Osterhoudt, KC, Mollen, CJ, et al. Extracorporeal membrane oxygenation as a resuscitative measure in the pediatric emergency department. Pediatr Emerg Care 2000;16:413415, doi:10.1097/00006565-200012000-00008.CrossRefGoogle ScholarPubMed
9. Fiser, RT, Morris, MC. Extracorporeal cardiopulmonary resuscitation in refractory pediatric cardiac arrest. Pediatr Clin North Am 2008;55:929941, doi:10.1016/j.pcl.2008.04.003.CrossRefGoogle ScholarPubMed
10. Maclaren, G, Butt, W, Best, D, et al. Extracorporeal membrane oxygenation for refractory septic shock in children: one institution’s experience. Pediatr Crit Care Med 2007;8:447451, doi:10.1097/01.PCC.0000282155.25974.8F.CrossRefGoogle ScholarPubMed
11. Shinar, Z, Bellezzo, JM, Paradis, N, et al. Emergency department initiation of cardiopulmonary bypass: a case report and review of the literature. J Emerg Med 2012;43:8386, doi:10.1016/j.jemermed.2011.06.134.CrossRefGoogle ScholarPubMed
12. Paden, ML, Conrad, SA, Rycus, PT, et al. Extracorporeal Life Support Organization Registry report 2012. ASAIO J 2013;59:202210, doi:10.1097/MAT.0b013e3182904a52.CrossRefGoogle ScholarPubMed
13. Maclaren, G, Butt, W, Cameron, P, et al. Treatment of polypharmacy overdose with multimodality extracorporeal life support. Anaesth Intensive Care 2005;33:120123.CrossRefGoogle ScholarPubMed
14. Sojod, G, Diana, M, Wall, J, et al. Successful extracorporeal membrane oxygenation treatment for pheochromocytomainduced acute cardiac failure. Am J Emerg Med 2012;30(1017):e13, doi:10.1016/j.ajem.2011.05.006.CrossRefGoogle ScholarPubMed
15. Hifumi, T, Kiriu, N, Kato, H, et al. Survival after prolonged resuscitation from cardiac arrest due to diabetic ketoacidosis using extracorporeal life support. Am J Emerg Med 2013;31(892):e12.CrossRefGoogle ScholarPubMed
16. Kuroda, H, Masuda, Y, Imaizumi, H, et al. Successful extracorporeal membranous oxygenation for a patient with life-threatening transfusion-related acute lung injury. J Anesth 2009;23:424426, doi:10.1007/s00540-009-0760-5.CrossRefGoogle ScholarPubMed
17. Kukita, I, Okamoto, K, Sato, T, et al. Emergency extracorporeal life support for patients with near-fatal status asthmaticus. Am J Emerg Med 1997;15:566569, doi:10.1016/S0735-6757(97)90158-3.CrossRefGoogle ScholarPubMed
18. Huang, S-C, Wu, E-T, Chen, Y-S, et al. Extracorporeal membrane oxygenation rescue for cardiopulmonary resuscitation in pediatric patients. Crit Care Med 2008;36:16071613, doi:10.1097/CCM.0b013e318170b82b.CrossRefGoogle ScholarPubMed
19. Arlt, M, Philipp, A, Voelkel, S, et al. Extracorporeal membrane oxygenation in severe trauma patients with bleeding shock. Resuscitation 2010;81:804809, doi:10.1016/j.resuscitation.2010.02.020.CrossRefGoogle ScholarPubMed
20. Brown, DJA, Brugger, H, Boyd, J, et al. Accidental hypothermia. N Engl J Med 2012;367:19301938, doi:10.1056/NEJMra1114208.CrossRefGoogle ScholarPubMed
21. Shin, J-S, Lee, S-W, Han, G-S, et al. Successful extracorporeal life support in cardiac arrest with recurrent ventricular fibrillation unresponsive to standard cardiopulmonary resuscitation. Resuscitation 2007;73:309313, doi:10.1016/j.resuscitation.2006.09.011.CrossRefGoogle ScholarPubMed
22. Brunner, M-E, Siegenthaler, N, Shah, D, et al. Extracorporeal membrane oxygenation support as bridge to recovery in a patient with electrical storm related cardiogenic shock. Am J Emerg Med 2013;31(467):e16, doi:10.1016/j.ajem.2012.08.043.CrossRefGoogle Scholar
23. Cohen, MI, Gaynor, JW, Ramesh, V, et al. Extracorporeal membrane oxygenation for patients with refractory ventricular arrhythmias. J Thorac Cardiovasc Surg 1999;118:961963, doi:10.1016/S0022-5223(99)70072-3.CrossRefGoogle ScholarPubMed
24. Brown, DFM, Jaffer, FA, Baker, JN, et al. Case records of the Massachusetts General Hospital. Case 28-2013. A 52-year-old man with cardiac arrest after an acute myocardial infarction. N Engl J Med 2013;369:10471054, doi:10.1056/NEJMcpc1304164.CrossRefGoogle ScholarPubMed
25. Dunning, J, Levine, A. Best evidence topic report. Cardiopulmonary bypass and the survival of patients in cardiac arrest. Emerg Med J 2004;21:499501, doi:10.1136/emj.2004.016543.CrossRefGoogle ScholarPubMed
26. Avalli, L, Maggioni, E, Formica, F, et al. Favourable survival of in-hospital compared to out-of-hospital refractory cardiac arrest patients treated with extracorporeal membrane oxygenation:an Italian tertiary care centre experience. Resuscitation 2012;83:579583, doi:10.1016/j.resuscitation.2011.10.013.CrossRefGoogle ScholarPubMed
27. Haneya, A, Philipp, A, Diez, C, et al. A 5-year experience with cardiopulmonary resuscitation using extracorporeal life support in non-postcardiotomy patients with cardiac arrest. Resuscitation 2012;83:13311337, doi:10.1016/j.resuscitation.2012.07.009.CrossRefGoogle ScholarPubMed
28. Bellezzo, JM, Shinar, Z, Davis, DP, et al. Emergency physician-initiated extracorporeal cardiopulmonary resuscitation. Resuscitation 2012;83:966970, doi:10.1016/j.resuscitation.2012.01.027.CrossRefGoogle ScholarPubMed
29. Jones, C, Hommers, C, Burns, B, et al. ECMO retrieval in NSW and beyond. Curr Anaesth Crit Care 2010;21:282286, doi:10.1016/j.cacc.2010.07.004.CrossRefGoogle Scholar
30. Foley, DS, Pranikoff, T, Younger, JG, et al. A review of 100 patients transported on extracorporeal life support. ASAIO J 2002;48:612619, doi:10.1097/00002480-200211000-00007.CrossRefGoogle ScholarPubMed
31. Lebreton, G, Pozzi, M, Luyt, C-E, et al. Out-of-hospital extra-corporeal life support implantation during refractory cardiac arrest in a half-marathon runner. Resuscitation 2011;82:12391242, doi:10.1016/j.resuscitation.2011.04.002.CrossRefGoogle Scholar
32. Arlt, M, Philipp, A, Voelkel, S, et al. Early experiences with miniaturized extracorporeal life-support in the catheterization laboratory. Eur J Cardiothorac Surg 2012;42:858863, doi:10.1093/ejcts/ezs176.CrossRefGoogle ScholarPubMed