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Dexamethasone in acute bacterial meningitis

Published online by Cambridge University Press:  21 May 2015

Darren Nichols*
Affiliation:
Department of Emergency Medicine, University of Alberta, Calgary, Alta.
Victor Jordan*
Affiliation:
Department of Emergency Medicine, University of Alberta, Calgary, Alta.

Abstract

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Type
CJEM Journal Club • Club de lecture JCMU
Copyright
Copyright © Canadian Association of Emergency Physicians 2003

References

1.Koedel, U, Scheld, WM, Pfister, HW.Pathogenesis and pathophysiology of pneumococcal meningitis. Lancet Infect Dis 2002;2:72136.Google Scholar
2.McIntyre, PB, Berkey, CS, King, SM, Schaad, UB, Kilpi, T, Kanra, GY, et al. Dexamethasone as adjunctive therapy in bacterial meningitis. A meta-analysis of randomized clinical trials since 1988. JAMA 1997;278(11):92531.CrossRefGoogle ScholarPubMed
3.Girgis, NI, Farid, Z, Kilpatrick, ME, Bishai, E.Dexamethasone treatment for bacterial meningitis in children and adults. Ped Infect Dis J 1989;8:84851.CrossRefGoogle ScholarPubMed
4.Townsend, GC, Scheld, WM.The use of corticosteroids in the management of bacterial meningitis in adults. J Antimicr Chemo 1996;37:105161.CrossRefGoogle ScholarPubMed
5.Thomas, R, Le Tulzo, Y, Bouget, J, Camus, C, Michelet, C, Le Corre, P, et al. Trial of dexamethasone treatment for severe bacterial meningitis in adults. Int Care Med 1999;25:47580.Google Scholar
6.Gijwani, D, Kumhar, MR, Singh, VB, Chadda, VS, Soni, PK, Nayak, KC, et al. Dexamethasone therapy for bacterial meningitis in adults: a double blind placebo controlled study. Neurol India 2002;50:637.Google Scholar
7.Blondell-Hill, E, Fryters, S.Bugs and drugs: antimicrobial pocket reference. Edmonton: Capital Health Authority; 2001.Google Scholar
8.Martinez-Lacasa, J, Cabellos, C, Martos, A, Fernandez, A, Tubau, F, Viladrich, PF, et al. Experimental stud in the efficacy of vancomycin, rifampin and dexamethasone in the therapy of pneumococcal meningitis. J Antimicrob Chemother 2002 49:50713.Google Scholar
9.Annane, D.Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002;288(7) 86285.Google Scholar
10.Abraham, E.Corticosteroids and septic shock. JAMA 2002; 288(7):8867.Google Scholar