Neuroethics to date has tended to focus on social and ethical implications of developments in brain science, especially in functional neuroimaging. Within clinical neuroethics, the emphasis has been on ethical issues in clinical neuroscience practice, including informed consent to neuroimaging; the development of ethical research protocols for functional magnetic resonance imaging especially, and especially in children; and the ethical clinical management of incidental findings. Within normative neuroethics, we have witnessed the more philosophical and/or social scientific study of the meanings of developments in neuroscience, including concerns about the impact of neuroimaging on privacy, freedom of thought, moral culpability, and sense of self. In this piece, I argue for an expansion of neuroethical attention to the interface of neuroscience and psychiatry, where brain science meets the clinical sciences of the mind. My particular focus is the development of psychiatric classification systems.I am grateful to Jenny Brian, Carl Craver, Thane Plantikow, Claire Pouncey, and Ken Schaffner for discussion of many of the themes presented here. Early research on which portions of this article are based was funded by the Canadian Institutes of Health Research in the form of an operating grant and salary award. My current research is supported by the Institute for Humanities Research, the Center for Biology and Society, and the School of Life Sciences, Arizona State University.