There is power in the choices we make in that our choices exercise and express our values. Choices, as compared with preferences, which may be spontaneous, are acts of deliberate volition—ways of casting our lot between alternatives. For this Special Section, “The Power of Choice: Autonomy, Informed Consent, and the Right to Refuse” we've chosen a frontispiece showing a balance with one pan offset by a weight in the shape of a human head. It graphically depicts that what is really in the balance in health decisions is the reflection of who we are.