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The significance of BHC degradation in resistant house-flies

Published online by Cambridge University Press:  10 July 2009

J. R. Busvine  and
M. G. Townsend
J. R. Busvine
Affiliation:
London School of Hygiene and Tropical Medicine
M. G. Townsend
Affiliation:
London School of Hygiene and Tropical Medicine
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Extract

Resistance to γ BHC and dieldrin in various insects usually gives a characteristic resistance spectrum, probably indicating a common defence mechanism. Resistant house-flies (Musca domestica L.) are slightly anomalous in showing greater tolerance of γ BHC than of endrin and isodrin, unlike other resistant strains. A possible explanation is that they can develop an additional defence, specific towards γ BHC, as well as the usual group resistance. This might well be enhanced enzymatic degradation of BHC, which is known to occur in flies, but was not found in resistant strains of Anopheles gambiae Giles or Cimex lectularius L.

To confirm this hypothesis the rates of BHC elimination were measured in normal and two resistant strains of flies and also in normal and resistant strains of Lucilia cuprina (Wied.) (which showed the more usual resistance spectrum). To avoid toxic effects, the non-insecticidal α BHC was used and its elimination after six hours measured in extracts by gas chromatography. The two resistant fly strains showed significantly increased degradation of BHC, correlated with their greater γ BHC resistance, whereas rates were about the same in normal flies and the two strains of L. cuprina.

Type
Research Paper
Information
Bulletin of Entomological Research , Volume 53 , Issue 4 , January 1963 , pp. 763 - 768
Copyright
Copyright © Cambridge University Press 1963

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References

Barbesgaard, P. & Keiding, J. (1955). Crossing experiments with insecticide-resistant house flies (Musca domestica L.).—Vidensk. Medd. dansk naturh. Foren. 117 pp. 84–116.Google Scholar
Bradbury, F. R. (1957). Absorption and metabolism of BHC in susceptible and resistant houseflies.—J. Sci. Fd Agric. 8 pp. 90–96.CrossRefGoogle Scholar
Bradbury, F. R. & Standen, H. (1955). The fate of γ-benzene hexachloride in normal and resistant houseflies. I.—J. Sci. Fd Agric. 6 pp. 90–99.CrossRefGoogle Scholar
Bradbury, F. R. & Standen, H. (1956). Benzene hexachloride metabolism in Anopheles gambiae.—Nature, Lond. 178 pp. 1053–1054.CrossRefGoogle ScholarPubMed
Bradbury, F. R. & Standen, H. (1958). The fate of γ-benzene hexachloride in resistant and susceptible houseflies. III.—J. Sci. Fd Agric. 9 pp. 203–212.CrossRefGoogle Scholar
Bradbury, F. R. & Standen, H. (1960). Mechanisms of insect resistance to the chlorohydrocarbon insecticides.—J. Sci. Fd Agric. 11 pp. 92–100.CrossRefGoogle Scholar
Bridges, R. G. & Cox, J. T. (1959). Resistance of houseflies to γ-benzene hexachloride and dieldrin.—Nature, Lond. 184 pp. 1740–1741.CrossRefGoogle Scholar
Brooks, G. T. (1960). Mechanisms of resistance of the adult housefly (Musca domestica) to ‘ cyclodiene ’ insecticides.—Nature, Lond. 186 pp. 96–98.CrossRefGoogle ScholarPubMed
Busvine, J. R. (1954). Houseflies resistant to a group of chlorinated hydrocarbon insecticides.—Nature, Lond. 174 pp. 783–785.CrossRefGoogle ScholarPubMed
Busvine, J. R. (1958). Insecticide-resistance in bed-bugs.—Bull. World Hlth Org. 19 pp. 1041–1052.Google ScholarPubMed
Busvine, J. R. (1959). Patterns of insecticide resistance to organo-phosphorus compounds in strains of houseflies from various sources.—Ent. exp. appl. 2 pp. 58–67.CrossRefGoogle Scholar
Busvine, J. R. (1962). A laboratory technique for measuring the susceptibility of houseflies and blowflies to insecticides.—Lab. Pract. 11 pp. 464–468.Google Scholar
Busvine, J. R. & Khan, N. H. (1955). Inheritance of BHC-resistance in the housefly.—Trans. R. Soc. trop. Med. Hyg. 49 pp. 455–459.CrossRefGoogle ScholarPubMed
Busvine, J. R. & Lien, J. (1961). Methods for measuring insecticide susceptibility levels in bed-bugs, cone-nosed bugs, fleas and lice.—Bull. World Hlth Org. 24 pp. 509–517.Google ScholarPubMed
Busvine, J. R. & Shanahan, G. J. (1961). The resistance spectrum of a dieldrin-resistant strain of the blowfly (Lucilia cuprina Wied.).—Ent. exp. appl. 4 pp. 1–6.CrossRefGoogle Scholar
Cochran, D. G. (1961). Further studies on cross-resistance in the German cockroach.—Bull. World Hlth Org. 24 pp. 557–561.Google ScholarPubMed
Davidson, G. (1958). Studies on insecticide resistance in Anopheline mosquitos.—Bull. World Hlth Org. 18 pp. 579–621.Google ScholarPubMed
Goodwin, E. S., Goulden, R. & Reynolds, J. G. (1961). Rapid identification and determination of residues of chlorinated pesticides in crops by gas-liquid chromatography.—Analyst 86 pp. 697–709.CrossRefGoogle Scholar
Lovelock, J. E. (1961). Affinity of organic compounds for free electrons with thermal energy: its possible significance in biology.—Nature, Lond. 189 pp. 729–732.CrossRefGoogle ScholarPubMed
Moore, A. D. (1962). Electron capture with an argon ionization detector in gas chromatographic analysis of insecticides.—J. econ. Ent. 55 pp. 271–272.CrossRefGoogle Scholar
Oppenoorth, F. J. (1955). Differences between rates of metabolism of benzene hexachloride in resistant and susceptible houseflies.—Nature, Lond. 175 pp. 124–125.CrossRefGoogle ScholarPubMed
Oppenoorth, F. J. (1956). Resistance to gamma-hexachlorocyclohexane in Musca domestica L.—Arch, néerl. Zool. 12 pp. 1–62.CrossRefGoogle Scholar
Sternburg, J. & Kearns, C. W. (1956). Pentachlorocyclohexene, an intermediate in the metabolism of lindane by house flies.—J. econ. Ent. 49 pp. 548–552.CrossRefGoogle Scholar