Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-22T05:53:09.295Z Has data issue: false hasContentIssue false
  • English
  • Français

Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae)

Published online by Cambridge University Press:  09 March 2007

B.D. Brooke ,
G. Kloke ,
R.H. Hunt ,
L.L. Koekemoer ,
E.A. Tem ,
M.E. Taylor ,
G. Small ,
J. Hemingway  and
M. Coetzee
B.D. Brooke*
Affiliation:
Medical Entomology, Department of Clinical Microbiology and Infectious Diseases School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, PO Box 1038, Johannesburg 2000, South Africa
G. Kloke
Affiliation:
Foray Consultants, 20 Melmoth Road, Eshowe, South Africa
R.H. Hunt
Affiliation:
Department of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, South Africa
L.L. Koekemoer
Affiliation:
Medical Entomology, Department of Clinical Microbiology and Infectious Diseases School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, PO Box 1038, Johannesburg 2000, South Africa
E.A. Tem
Affiliation:
Medical Entomology, Department of Clinical Microbiology and Infectious Diseases School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, PO Box 1038, Johannesburg 2000, South Africa
M.E. Taylor
Affiliation:
Medical Entomology, Department of Clinical Microbiology and Infectious Diseases School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, PO Box 1038, Johannesburg 2000, South Africa
G. Small
Affiliation:
School of Biosciences, University of Wales, Cardiff, UK
J. Hemingway
Affiliation:
School of Biosciences, University of Wales, Cardiff, UK
M. Coetzee
Affiliation:
Medical Entomology, Department of Clinical Microbiology and Infectious Diseases School of Pathology of the South African Institute for Medical Research and the University of the Witwatersrand, PO Box 1038, Johannesburg 2000, South Africa
*
*Fax: +27 11 489 9399 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Anopheles funestus Giles has been implicated as a major malaria vector in sub-Saharan Africa where pyrethroid insecticides are widely used in agriculture and public health. Samples of this species from northern Kwazulu/Natal in South Africa and the Beluluane region of southern Mozambique showed evidence of resistance to pyrethroid insecticides. Insecticide exposure, synergist and biochemical assays conducted on A. funestus suggested that elevated levels of mixed function oxidases were responsible for the detoxification of pyrethroids in resistant mosquitoes in these areas. The data suggested that this mechanism was also conferring cross-resistance to the carbamate insecticide propoxur.

Type
Research Article
Information
Bulletin of Entomological Research , Volume 91 , Issue 4 , August 2001 , pp. 265 - 272
Copyright
Copyright © Cambridge University Press 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brogdon, W.G. & McAllister, J.C. (1998) Simplification of adult mosquito bioassays through use of time-mortality determinations in glass bottles. Journal of the American Mosquito Control Association 14, 159–167.Google ScholarPubMed
Brooke, B.D., Hunt, R.H., Koekemoer, L.L., Dossou-Yovo, J. & Coetzee, M. (1999) Evaluation of a PCR assay for detection of pyrethroid insecticide resistance in the malaria vector species of the Anopheles gambiae complex (Diptera: Culicidae). Journal of the American Mosquito Control Association 15, 565–568.Google Scholar
Chandre, F., Darriet, F., Manga, L., Akogbeto, M., Faye, O., Mouchet, J. & Guillet, P. (1999) Status of pyrethroid resistance in Anopheles gambiae s.l. Bulletin of the World Health Organization 77, 230–234.Google Scholar
Cochran, D. (1987) Effects of synergists on bendiocarb and pyrethrins resistance in the German cockroach (Dictyoptera: Blattellidae). Journal of Economic Entomology 80, 728–732..CrossRefGoogle ScholarPubMed
Coetzee, M. & Hunt, R.H. (1998) Malaria at its southern-most fringe in Africa. Research Reviews in Parasitology 58, 175–179.Google Scholar
Coetzee, M., Horne, D.W.K., Brooke, B.D. & Hunt, R.H. (1999) DDT, dieldrin and pyrethroid insecticide resistance in African malaria vector mosquitoes: an historical review and implications for future malaria control in southern Africa. South African Journal of Science 95, 215–218.Google Scholar
Curtis, C.F., Hill, N. & Kasim, H. (1993) Are there effective resistance management strategies for vectors of human disease? Biological Journal of the Linnean Society 48, 3–18.CrossRefGoogle Scholar
Davidson, G. (1956) Insecticide resistance in Anopheles gambiae Giles: a case of simple Mendelian inheritance. Nature 178, 863–864.CrossRefGoogle Scholar
De Meillon, B., Van Eeden, G.J., Coetzee, L., Coetzee, M., Meiswinkel, R., Du Toit, C.L.N. & Hansford, C.F. (1977) Observations on a species of the Anopheles funestus subgroup, a suspected exophilic vector of malaria parasites in northeastern Transvaal, South Africa. Mosquito News 37, 657–661.Google Scholar
Elissa, N., Mouchet, J., Riviere, F., Meunier, J.Y. & Yao, K. (1993) Resistance of Anopheles gambiae ss to pyrethroids in Cote d'Ivoire. Annales de la Société Belge de Médicine Tropicale 73, 291–294.Google ScholarPubMed
Gillies, M.T. & Coetzee, M. (1987) A supplement to the Anophelinae of Africa south of the Sahara. Publications of the South African Institute for Medical Research, Johannesburg, 55.Google Scholar
Gillies, M.T. & De Meillon, B. (1968) The Anophelinae of Africa south of the Sahara. 2nd edn. Publications of the South African Institute for Medical Research, Johannesburg, 54.Google Scholar
Hargreaves, K., Koekemoer, L.L., Brooke, B.D., Hunt, R.H., Mthembu, J. & Coetzee, M. (2000) Anopheles funestus resistant to pyrethroid insecticides in South Africa. Medical and Veterinary Entomology 14, 181–189.CrossRefGoogle ScholarPubMed
Hemingway, J. & Georghiou, G.P. (1983) Studies on the acetylcholinesterase of Anopheles albimanus resistant and susceptible to organophosphate and carbamate insecticides. Pesticide and Biochemical Physiology 19, 167–171.CrossRefGoogle Scholar
Hemingway, J. & Ranson, H. (2000) Insecticide resistance in insect vectors of human disease. Annual Review of Entomology 45, 371–391..CrossRefGoogle ScholarPubMed
Hemingway, J., Hawkes, N., Prapanthadara, L., Jayawardena, K.G.I. & Ranson, H. (1998) The role of gene splicing, gene amplification and regulation in mosquito insecticide resistance. Philosophical Transactions of the Royal Society of London Series B 353, 1695–1699.CrossRefGoogle ScholarPubMed
Koekemoer, L.L., Lochouarn, L., Hunt, R.H. & Coetzee, M. (1999) Single-strand conformation polymorphism analysis for identification of four members of the Anopheles funestus (Diptera: Culicidae) group. Journal of Medical Entomology 36, 125–130..CrossRefGoogle ScholarPubMed
Lacey, L.A. & Lacey, C.M. (1990) The medical importance of riceland mosquitoes and their control using alternatives to chemical insecticides. Journal of the American Mosquito Control Association 6, supplement 2.Google Scholar
Martinez-Torres, D., Chandre, F., Williamson, M.S., Darriet, F., Berge, J.B., Devonshire, A.L., Guillet, P., Pasteur, N. & Pauron, D. (1998) Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae ss. Insect Molecular Biology 7, 179–184..CrossRefGoogle Scholar
Park Ross, G.A. (1936) Insecticide as a major measure in the control of malaria, being an account of the methods and organizations put into force in Natal and Zululand during the past six years. Quarterly Bulletin of the Health Organization of the League of Nations 5, 114–133.Google Scholar
Penilla, R.P., Rodriguez, A.D., Hemingway, J., Torres, J.L., Arrendo-Jimenez, J.I. & Rodriguez, M.H. (1998) Resistance management strategies in malaria vector mosquito control. Baseline data for a large scale field trial against Anopheles albimanus in Mexico. Medical and Veterinary Entomology 12, 217–233..CrossRefGoogle ScholarPubMed
Phillips, R.S. (2001) Current status of malaria and potential for control. Clinical Microbiology Reviews 14, 208–226..CrossRefGoogle ScholarPubMed
Ranson, H., Jenson, B., Vulule, J.M., Wang, X., Hemingway, J. & Collins, F.H. (2000) Identification of a novel mutation in the voltage-gated sodium channel gene of Anopheles gambiae associated with resistance to pyrethroid insecticides. Insect Molecular Biology 9, 491–498..CrossRefGoogle Scholar
Roberts, D.R. & Andre, R.G. (1994) Insecticide resistance issues in vector-borne disease control. American Journal of Tropical Medicine and Hygiene 50, supplement 21–34.CrossRefGoogle ScholarPubMed
Scott, J.A., Brogdon, W.G. & Collins, F.H. (1993) Identification of single specimens of the Anopheles gambiae complex by the polymerase chain reaction. American Journal of Tropical Medicine and Hygiene 49, 520–529.CrossRefGoogle ScholarPubMed
Snow, R.W., Craig, M.H., Deichmann, U. & Le Sueur, D. (1999) A preliminary continental risk map for malaria mortality among African children. Parasitology Today 15, 99–104.CrossRefGoogle Scholar
Temu, E.A., Minjas, J.N., Coetzee, M., Hunt, R.H. & Shiff, C.J. (1998) The role of four anopheline species (Diptera: Culicidae) in malaria transmission in coastal Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene 92, 152–158.CrossRefGoogle Scholar
Vulule, J.M., Beach, R.F., Atieli, F.K., Mount, D.L., Roberts, J.M. & Mwangu, R.W. (1999) Reduced susceptibility of Anopheles gambiae to permethrin associated with the use of permethrin impregnated bed nets and curtains in Kenya. Medical and Veterinary Entomology 8, 71–75.CrossRefGoogle Scholar
Wilkes, T., Matola, Y.G. & Charlwood, J.D. (1996) Anopheles rivulorum, a vector of human malaria in Africa. Medical and Veterinary Entomology 10, 108–110.CrossRefGoogle Scholar
World Health Organization (1996) World Health Report.WHO,Geneva, Switzerland.Google Scholar
World Health Organization (1998) Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. Document WHO/CDS/CPC/MAL/98.12. Geneva, Switzerland.Google Scholar