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A veterinary model for the induction of primary nutritional ketosis in dairy cattle

Published online by Cambridge University Press:  27 February 2018

H. R. Whay
Affiliation:
University of Edinburgh, Department of Clinical Veterinary Studies, Roslin, Midlothian EH25 9RG
D. A. Whitaker
Affiliation:
University of Edinburgh, Department of Clinical Veterinary Studies, Roslin, Midlothian EH25 9RG
T. T. Mottram
Affiliation:
Silsoe Research Institute, Wrest Park, Silsoe, Bedford MK45 4HS
A. M. Dowell
Affiliation:
University of Edinburgh, Department of Clinical Veterinary Studies, Roslin, Midlothian EH25 9RG
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Abstract

A method for inducing primary nutritional ketosis in dairy cattle was developed in order to evaluate a novel technique for the monitoring of the development of ketosis through to clinical disease state. Six freshly calved, multiparous Holstein-Friesian cows were given a 500 g/kg crude protein pellet in small but frequent meals through an out-of-parlour feeder in conjunction with an allowance of grass silage restricted to 20 kg wet weight per day. Development of the disease was monitored through clinical signs, body condition scoring, weight change measures and metabolic profiling of plasma samples with particular reference to beta-hydroxybutyrate, non-esterified fatty acid and glucose levels. Four animals within the disease model group became clinically ketotic with the remaining two animals showing signs of subclinical ketosis. A further four newly calved cows, which were maintained on a normal production ration to act as a control group, did not develop signs of ketosis.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1999

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