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Cellular growth - the key to animal growth

Published online by Cambridge University Press:  27 February 2018

C. Goddard
C. Goddard*
Affiliation:
A.F.R.C. Institute of Animal Physiology and Genetics Research, Edinburgh Research Station, Roslin, Midlothian, EH25 9PS. U.K.
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Abstract

There is an increasing possibility that animal performance may be manipulated by new techniques incorporated into efficient breeding programmes. In order to fully exploit these techniques to increase the efficiency of growth, gene products involved in the control of growth, development and also reproduction must be identified. Correct expression or manipulation of these genes to provide optimum effect on a trait requires complete knowledge of their biological action. The transgenic approach has provided some success using growth hormone and growth hormone releasing hormone to increase growth in mice. Further possibilities exist, since recent work suggests that peptide growth factors such as the insulin-like growth factors, fibroblast growth factor and transforming growth factor-β may be primary regulators of normal growth. This brief overview introduces some of these peptide growth factors, provides basic information on them and offers them for discussion as potential targets for manipulation.

Type
Aspects of the Control of Growth
Information
BSAP Occasional Publication , Volume 12: Animal Breeding Opportunities , 1988 , pp. 182 - 188
Copyright
Copyright © British Society of Animal Production 1988

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References

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