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Wheat bran supplementation does not affect biochemical markers of bone turnover in young adult women with recommended calcium intake

Published online by Cambridge University Press:  09 March 2007

A. Zittermann ,
K. Scheld ,
A. Danz  and
P. Stehle
A. Zittermann*
Affiliation:
Department of Nutrition Science, University of Bonn, Endenicher Allee 11-13, 53115 Bonn, Germany
K. Scheld
Affiliation:
Department of Nutrition Science, University of Bonn, Endenicher Allee 11-13, 53115 Bonn, Germany
A. Danz
Affiliation:
Department of Biology and Education, Health Education, University of Cologne, Cologne, Germany
P. Stehle
Affiliation:
Department of Nutrition Science, University of Bonn, Endenicher Allee 11-13, 53115 Bonn, Germany
*
*Corresponding author: Dr Armin Zittermann, fax +49 228 733217, email [email protected]
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Abstract

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We investigated the effect of wheat bran on biochemical indicators of Ca and bone metabolism in nineteen healthy women, aged 25·5 (se 0·9) years. Subjects received six wheat bran biscuits or six white flour biscuits per day for a period of 4 weeks (crossover). Wheat bran consumption increased fibre intake from 17·7 (se 1·3) to 29·6 (se 1·3) g/d (7 d food record) and enhanced P intake from 1225 (se 59) mg/d to 1663 (se 65) mg/d; P < 0·001. Mean daily Ca intake during wheat bran consumption (1110 (se 82) mg/d) significantly (P = 0·008) exceeded Ca ingestion during the white flour period (955 (se 67) mg/d). Wheat bran increased the number of defecations per week from 7·9 (se 0·8) to 12·2 (se 1·4) (P = 0·0018). Urinary Ca excretion over 24 h significantly (P = 0·021) decreased from 473 (se 53) μmol/mmol creatinine (control period) to 339 (se 37) μmol/mmol creatinine (wheat bran period). Serum 25-hydroxyvitamin D, 2 h fasting urinary Ca/creatinine excretions and 24 h urinary P excretion remained constant. No differences in serum levels of carboxy-terminal propeptide of type I procollagen (biomarker of bone formation) or in 2 h fasting urinary hydroxyproline/creatinine excretions (biomarker of bone resorption) were observed at the end of the two cycles of dietary supplementation. We conclude that a high fibre intake of approximately 30 g/d has no significant adverse effects on bone turnover in subjects with Ca intakes above 1000 mg/d and that the reduction in 24 h urinary Ca excretion is most probably the result of an adaptation process, induced by a decrease in net absorbed Ca.

Keywords

Wheat branCalciumBone turnover
Type
Short communication
Information
British Journal of Nutrition , Volume 82 , Issue 6 , December 1999 , pp. 431 - 435
Copyright
Copyright © The Nutrition Society 1999

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