Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-05T04:19:08.587Z Has data issue: false hasContentIssue false

Vitamin A status and the metabolism of cholesterol in the rat

Published online by Cambridge University Press:  09 March 2007

M. R. Lakshmanan
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
W. E. J. Phillips
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
R. L. Brien
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The interrelationship between cholesterol and vitamin A metabolism has been studied in rats.

2. The effect of cholesterol feeding in increasing the liver storage of cholesterol w-as enhanced during vitamin A deficiency.

3. This effect was due to an increased rate of absorption of cholesterol and not due to a decreased turnover rate.

4. Feeding of high levels of vitamin A markedly depressed the cholesterol absorption; however, its turnover was unaffected.

Type
Research Article
Copyright
Copyright © The Nutrition Society 1969

References

Ahrens, E. H. Jr, Insull, W. Jr, Hirsch, J., Stoffel, W., Peterson, M., Farquhar, J. W., Miller, T. & Thompson, H. J. (1959). Lancet i, 115.CrossRefGoogle Scholar
Anderson, J. T., Keys, A. & Grande, F. (1957). J. Nutr. 62, 421.CrossRefGoogle Scholar
Beeler, D. A., Rogler, J. C. & Quackenbush, F. W. (1962). J. Nutr. 78, 184.CrossRefGoogle Scholar
Bring, S. V., Ricard, C. A. & Zaehringer, M. V. (1965). J. Nutr. 85, 400.CrossRefGoogle Scholar
Bronte-Stewart, B., Antonis, A., Eales, L. & Brock, J. F. (1956). Lancet i, 521.CrossRefGoogle Scholar
DeGroot, A. P. & Reed, S. A. (1959). Nature, Lond. 183, 1191.CrossRefGoogle Scholar
Green, B., Horner, A. A., Lowe, J. S. & Morton, R. A. (1957). Biochem. J. 67, 235.CrossRefGoogle Scholar
Horner, A. A. & Morton, R. A. (1960). Biochem. J. 74, 301.CrossRefGoogle Scholar
March, B. E. & Biely, J. (1963). J. Nutr. 79, 474.CrossRefGoogle Scholar
Mervyn, L. & Morton, R. A. (1959). Biochem. J. 72, 106.CrossRefGoogle Scholar
Phillips, W. E. J. (1961). Can. J. Biochem. Physiol. 39, 855.CrossRefGoogle Scholar
Phillips, W. E. J. (1967). Can. J. Biochem. 45, 749.CrossRefGoogle Scholar
Sampson, M. M. & Potter, L. M. (1947). Fedn Proc. Fedn Am. Socs exp. Biol. 6, 420.Google Scholar
Weitzel, G., Schön, H., Gey, F. & Buddecke, E. (1956). Hoppe-Seylers 2. physiol. Chem. 304, 247.CrossRefGoogle Scholar
Wood, J. D. (1960). Can. J. Biochem. Physiol. 38, 879.CrossRefGoogle Scholar
Wood, J. D. & Topliff, J. (1961). J. Fish. Res. Bd Can. 18, 377.CrossRefGoogle Scholar