Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-29T08:25:17.882Z Has data issue: false hasContentIssue false
  • English
  • Français

The utilization of protein and energy during lactation in the rat, with particular regard to the use of fat accumulated in pregnancy

Published online by Cambridge University Press:  09 March 2007

D. J. Naismith ,
D. P. Richardson  and
Ann E. Pritchard
D. J. Naismith
Affiliation:
Department of Food Science and Nutrition, Queen Elizabeth College, University of London, London W8 7AH
D. P. Richardson
Affiliation:
Department of Food Science and Nutrition, Queen Elizabeth College, University of London, London W8 7AH
Ann E. Pritchard
Affiliation:
Department of Food Science and Nutrition, Queen Elizabeth College, University of London, London W8 7AH
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The deposition of fat during pregnancy and its subsequent mobilization during lactation was studied in the rat. The utilization of protein during lactation was also investigated.

2. Fat accumulation was rapid and continuous from early pregnancy. Approximately one-third was deposited subcutaneously, the remainder being stored in central depots.

3. The volume of milk produced during lactation was varied by offering protein at two concentrations from day 2 post partum. Optimum lactation was achieved with a high-protein diet. The dams lost no body protein, but 60% of the total body fat was mobilized, despite a marked increase in food consumption. On a low-protein diet, food intake did not rise during lactation. Some body protein was catabolized and, again, 60% of the fat was mobilized although milk output, as judged by the gain in carcass energy of their pups, was reduced to approximately one-third of optimum.

4. Protein was used more efficiently by lactating rats, when compared with virgin controls.

5. We conclude that fat stored during pregnancy makes a major contribution to the energy costs of lactation, and that its mobilization is under hormonal rather than dietary control.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 48 , Issue 2 , September 1982 , pp. 433 - 441
Copyright
Copyright © The Nutrition Society 1982

References

REFERENCES

Beaton, G. H., Beare, J., Ryu, M. H. & McHenry, E. W. (1954). J. Nutr. 54, 291.CrossRefGoogle Scholar
Brown, G. W. Jr & Cohen, P. P. (1959). J. biol. Chem. 234, 1769.Google Scholar
Brown, G. W. Jr & Cohen, P. P. (1960). Biochem. J. 75, 82.CrossRefGoogle Scholar
Folch, J., Lees, M. & Sloane-Stanley, G. H. (1957). J. biol. Chem. 226, 497.Google Scholar
Hervey, E. & Hervey, G. R. (1967). J. Endocr. 37, 361.CrossRefGoogle Scholar
Hytten, F. E. (1980). In Clinical Physiology in Obstetrics, p. 181 [Hytten, F. E. and Chamberlain, G., editors]. London: Blackwell.Google Scholar
Kennedy, G. C., Pearce, W. M. & Parrott, D. M. V. (1958). J. Endocr. 17, 158.CrossRefGoogle Scholar
Naismith, D. J. (1966). Metabolism 15, 582.Google Scholar
Naismith, D. J. (1971). Proc. Nutr. Soc. 32, 93A.Google Scholar
Naismith, D. J. (1980). In Maternal Nutrition During Pregnancy and Locatation, p. 16. [Aebi, H. and Whitehead, R., editors]. Bern: Huber.Google Scholar
Naismith, D. J., Akinyanju, P. A. & Yudkin, J. (1969). J. Nutr. 97, 375.Google Scholar
Naismith, D. J. & Fears, R. B. (1971). Proc. Nutr. Soc. 31, 8A.Google Scholar
Naismith, D. J. & Morgan, B. L. G. (1976). Br. J. Nutr. 36, 563.CrossRefGoogle Scholar
Niiyama, Y., Endo, S., Kamori, K. & Inoue, G. (1973). Nutr. Rep. Int. 8, 61.Google Scholar
Ratner, S. (1955). In Methods in Enzymology, vol 11, p. 356 [Clayton, R. B., editor]. London: Academic Press.Google Scholar
Schimke, R. T. (1962). J. biol. Chem. 235, 459.CrossRefGoogle Scholar
Spray, C. M. (1950). Br. J. Nutr. 4, 354.Google Scholar