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The urinary excretion of metabolites of riboflavine by man

Published online by Cambridge University Press:  09 March 2007

D. W. West  and
E. C. Owen
D. W. West
Affiliation:
Biochemistry Department, Hannah Dairy Research Institute, Ayr
E. C. Owen
Affiliation:
Biochemistry Department, Hannah Dairy Research Institute, Ayr
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Abstract

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1. A dose of 1 g of riboflavine caused a large excretion of the vitamin in human urine and the rate of excretion showed more than one maximum.

2. Various degradation products of riboflavine appeared in the urine approximately 24 h after the dose was administered and two of these were identified as 7,8-dimethyl-10-(2-hydroxy-ethyl)isoalloxazine, and 7,8-dimethyl-10-formyl-methylisoalloxazine. Reasons are given for believing that the degradation of riboflavine was due to bacterial action in the colon.

Type
Research Article
Information
British Journal of Nutrition , Volume 23 , Issue 4 , November 1969 , pp. 889 - 898
Copyright
Copyright © The Nutrition Society 1969

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