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Studies on the response of Lactobacillus casei to different folate monoglutamates

Published online by Cambridge University Press:  24 July 2007

D. R. Phillips
Affiliation:
Agricultural Research Council, Food Research Institute, Colney Lane, Norwich, Norfolk NR4 7UA
A. J. A. Wright
Affiliation:
Agricultural Research Council, Food Research Institute, Colney Lane, Norwich, Norfolk NR4 7UA
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Abstract

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1. The response of Lactobacillus casei was measured for a number of the monoglutamyl forms of folate derivatives.

2. At the concentrations of folate commonly used in the assay of folate vitamin in foods the response of L. casei to folic acid, (pteroyl glutamic acid) and 5-formyl-tetrahydrofolic acid was similar, but 5-methyl-tetrahydrofolic acid gave as little as half the response of folic acid.

3. The response was modified by altering pH but not by concentration of ascorbate.

4. These results have implications for the assays of foods for folate where mixtures of folate derivatives are present.

5. A modified procedure is suggested in which the monoglutamates give similar responses.

Type
Papers of direct reference to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1982

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