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Sodium bicarbonated mineral water decreases postprandial lipaemia in postmenopausal women compared to a low mineral water

Published online by Cambridge University Press:  08 March 2007

Stefanie Schoppen ,
Ana M. Pérez-Granados ,
Ángeles Carbajal ,
Beatriz Sarriá ,
Francisco J. Sánchez-Muniz ,
Juan A. Gómez-Gerique  and
M. Pilar Vaquero
Stefanie Schoppen*
Affiliation:
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Ana M. Pérez-Granados
Affiliation:
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Ángeles Carbajal
Affiliation:
Department of Nutrition, Faculty of Pharmacy, Madrid Complutense University, Madrid, Spain
Beatriz Sarriá
Affiliation:
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
Francisco J. Sánchez-Muniz
Affiliation:
Department of Nutrition, Faculty of Pharmacy, Madrid Complutense University, Madrid, Spain
Juan A. Gómez-Gerique
Affiliation:
Biochemical Service, Fundación Jimenez Díaz, Madrid, Spain
M. Pilar Vaquero
Affiliation:
Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain
*
*Corresponding author: Dr Stefanie Schoppen, fax +34 915493627, email [email protected]
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Abstract

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The role of bicarbonated mineral waters on lipid metabolism and lipoprotein concentrations in man has scarcely been investigated. The present study aimed to investigate whether drinking sodium bicarbonated mineral water affects postprandial cholesterol and triacylglycerol metabolism in postmenopausal women. In a three-way, randomised, crossover study, eighteen healthy postmenopausal women consumed two sodium bicarbonated mineral waters (bicarbonated mineral water 1 and bicarbonated mineral water 2) and a low mineral water (500 ml of each) with a standard fat-rich meal (4552 kJ; 75·3 g fat). The bicarbonated waters were rich in sodium and bicarbonate and bicarbonated mineral water 1 contained 5·7 times more fluoride than bicarbonated mineral water 2. Fasting blood samples and postprandial blood samples were taken at 30, 60, 120, 240, 360 and 420 min after the end of the meal consumption. Cholesterol and triacylglycerols were determined in serum and chylomicrons. A significant water consumption effect was observed in the total area under the curve (TAUC) of serum and chylomicron triacylglycerols (ANOVA, P=0·008 and P=0·027, respectively). TAUC of serum triacylglycerols for bicarbonated mineral water 2 was significantly lower compared to low mineral water (Bonferroni, P=0·039). Peak concentration of serum triacylglycerols showed a significant water effect (P=0·025). Changes in chylomicron cholesterol were not significantly affected by the type of water. Bicarbonated mineral waters 1 and 2 did not show any significant differences. Drinking sodium bicarbonate-rich mineral waters reduces postprandial lipaemia in healthy postmenopausal women compared to drinking a low mineral water.

Keywords

Sodium bicarbonateBicarbonated mineral waterPostprandial lipaemiaPostmenopausal women
Type
Research Article
Information
British Journal of Nutrition , Volume 94 , Issue 4 , October 2005 , pp. 582 - 587
Copyright
Copyright © The Nutrition Society 2005

References

Anti, M, Pignataro, G, Armuzzi, A et al. , (1998) Water supplementation enhances the effect of high-fiber diet on stool frequency and laxative consumption in adult patients with functional constipation. Hepatogastroenterology 45, 727–732.Google ScholarPubMed
Armijo, Valenzuela M (1994) Aguas bicarbonatadas. In Curas Balnearias y Climáticas. Talasoterapia y Heliaterapia, pp. 261–266 [Valenzuela, Armijo M and J San Martin, Bacaicoa, editors]. Madrid: Editorial Complutense.Google Scholar
Bertoni, M, Oliveri, F, Manghetti, M et al. , (2002) Effects of a bicarbonate-alkaline mineral water on gastric functions and functional dyspepsia: a preclinical and clinical study. Pharmacol Res 46, 525–531.CrossRefGoogle ScholarPubMed
Böhmer, H, Müller, H & Resch, KL (2000) Calcium supplementation with calcium rich mineral waters: a systematic review and meta-analysis of its bioavailability. Osteoporos Int 11, 938–943.Google ScholarPubMed
Buclin, T, Cosma, M, Appenzeller, M, Jacquet, AF, Decosterd, LA, Biollaz, J & Burckhardt, P (2001) Diet acids and alkalis influence calcium retention in bone. Osteoporos Int 12, 439–499.CrossRefGoogle ScholarPubMed
Capurso, A, Solfrizzi, V, Panza, F et al. , (1999) Increased bile acid excretion and reduction of serum cholesterol after crenotherapy with salt-rich mineral water. Aging (Milano) 11, 273–276.Google Scholar
Cepollaro, C, Orlandi, G, Gonelli, S et al. , (1996) Effect of calcium supplementation as a high-calcium mineral water on bone loss in early postmenopausal women. Calcif Tissue Int 59, 238–239.CrossRefGoogle Scholar
Chijiiwa, K & Linscheer, WG (1984) Effect on intraluminal pH on cholesterol and oleic acid absorption from micellar solution in the rat. Am J Physiol 246, G492–G499.Google ScholarPubMed
Chijiiwa, K & Linscheer, WG (1987) Mechanisms of pH effect on oleic acid and cholesterol absorption in the rat. Am J Physiol 252, G506–G510.Google ScholarPubMed
Chung, BH, Doran, S, Liang, P et al. , (2003) Alcohol mediated enhancement of postprandial lipaemia: a contributing factor to an increase in plasma HDL and decrease in risk of cardiovascular disease. Am J Clin Nutr 78, 391–399.CrossRefGoogle Scholar
Cohen, JC, Noakes, TD & Benade, AJ (1989) Postprandial lipaemia and chylomicron clearance in athletes and in sedentary men. Am J Clin Nutr 49, 443–447.CrossRefGoogle ScholarPubMed
Eberhardt, G, Dersidan, A, Nustede, R & Schafmeyer, A (1991) Neurotensin during the consumption of mineral water from Bad Mergentheimer Karlsquelle. Leber Magen Darm 21, 220–223.Google ScholarPubMed
Gill, JM & Hardman, AE (2003) Exercise and postprandial lipid metabolism: an update on potential mechanisms and interactions with high carbohydrate diets (review). J Nutr Biochem 14, 122–132.Google Scholar
Grassi, M, Lucchetta, MC, Grossi, F & Raffa, S (2002) Possibilities of thermal medicine in gastrointestinal functional disorders. Clin Ter 153, 195–206.Google ScholarPubMed
Guillemant, J, Le, HT, Accarie, C et al. , (2000) Mineral water as a source of dietary calcium: acute effects on parathyroid function and bone resorption in young men. Am J Clin Nutr 71, 999–1002.CrossRefGoogle ScholarPubMed
Hardman, AE & Herd, SL (1998) Exercise and postprandial lipid metabolism. Proc Nutr Soc 57, 63–72.Google Scholar
Hyson, D, Rutledge, JC & Berglund, L (2003) Postprandial lipemia and cardiovascular disease. Curr Atheroscler Rep 5, 437–444.CrossRefGoogle ScholarPubMed
Iovine, C, Gentile, A, Hattemer, A, Pacioni, D, Riccardi, G & Rivellese, AA (2004) Self monitoring of plasma triacyglyceride levels to evaluate postprandial response to different nutrients. Metabolism 43, 620–623.Google Scholar
Keogh, GF, Copper, GJS, Mulvey, TB et al. , (2003) Randomized controlled crossover study of the effect of a highly β-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men. Am J Clin Nutr 78, 711–718.CrossRefGoogle ScholarPubMed
Kris-Etherton, PM, Hecker, KD & Binkoski, AE (2004) Polyunsaturated fatty acids and cardiovascular health. Nutr Rev 62, 414–426.CrossRefGoogle ScholarPubMed
Lefevre, M, Kris-Etherton, PM, Zhao, G & Tracy, RP (2004) Dietary fatty acids, hemostasis, and cardiovascular disease risk. J Am Diet Assoc 104, 410–419.CrossRefGoogle ScholarPubMed
Linscheer, WG & Vergroesen, AJ (1994) Lipids in Modern Nutrition in Health and Disease, 8th ed., pp. 47–88. [Shils, ME, Olson, JA and Shike, M, editors]. Philadelphia: Lea & Febiger.Google Scholar
Luoma, H, Alakuijala, P, Korhonen, A, Nevalainen, T, Kuronen, M & Jauhiainen, M (1995) Serum lipoprotein levels in genetically hypercholesterolaemic RICO rats: effects of a high-sucrose-cholesterol diet without or with altered magnesium and fluoride contents. Scand J Clin Lab Invest 55, 495–503.CrossRefGoogle ScholarPubMed
Luoma, H, Metsä-Ketelä, T, Jauhiainen, M, Alakuijala, P, Korhonen, A & Nevalainen, T (1997) Effects of dietary fluoride and magnesium supplements on cyclic adenosine monophosphate (cAMP), calcium and magnesium levels in aorta of genetically hypercholesterolaemic RICO rats. Scand J Clin Lab Invest 57, 421–426.CrossRefGoogle ScholarPubMed
Marchi, S, Polloni, A, Bellini, M et al. , (1992) Evaluation of the efficacy of bicarbonate-alkaline water action on gallbladder motility. Minerva Med 83, 69–72.Google ScholarPubMed
Masding, MG, Wootton, SA, Stears, AJ, Sandemann, DD & Burdge, GC (2003) Premenopausal advantages in postprandial lipid metabolism are lost in women with type 2 diabetes. Diabetes Care 26, 3243–3249.CrossRefGoogle ScholarPubMed
Nerbrand, C, Agreus, L, Lenner, RA, Nyberg, P & Svardsudd, K (2003) The influence of calcium and magnesium in drinking water and diet on cardiovascular risk factors in individuals living in hard and soft water areas with differences in cardiovascular mortality. BMC Public Health 18, 21.CrossRefGoogle Scholar
Official Journal of the European Union (2003) Commission directive 2003/40/EC, 16 May, Annex I:L126/37.Google Scholar
Ostos, MA, Lopez-Miranda, J, Marin, C et al. , (2000) The apolipoprotein A-IV-360His polymorphism determines the dietary fat clearance in normal subjects. Atherosclerosis 153, 209–217.Google Scholar
Sanders, TA (2003) Dietary fat and postprandial lipids. Curr Atheroscler Rep 6, 445–451.CrossRefGoogle Scholar
Sauvant, MP & Pepin, D (2000) Geographic variation of the mortality from cardiovascular diseases and drinking water in a French small area (Puy de Dome). Environ Res Section A 84, 219–227.CrossRefGoogle Scholar
Schoppen, S, Pérez-Granados, AM, Carbajal, A et al. , (2004) A sodium-rich carbonated mineral water reduces cardiovascular risk in postmenopausal women. J Nutr 134, 1058–1063.CrossRefGoogle ScholarPubMed
Sethi, S, Gibney, M & Williams, CM (1993) Postprandial lipoprotein metabolism. Nutr Res RevM 69, 161–183.CrossRefGoogle Scholar
Siener, R, Jahnen, A & Hesse, A (2004) Influence of a mineral water rich in calcium, magnesium and bicarbonate on urine composition and the risk of calcium oxalate crystallization. Eur J Clin Nutr 58, 270–276.Google Scholar
Summers, LKM, Samra, JS & Frayn, KN (1999) Impaired postprandial tissue regulation of blood flow in insulin resistance: a determinant of cardiovascular risk? Atherosclerosis 147, 11–15.CrossRefGoogle ScholarPubMed
Szafran, H & Smielak-Korombel, W (1998) The role of estrogens in hormonal regulation of lipid metabolism in women. Przegl Lek 55, 266–270.Google ScholarPubMed
Tapola, NS, Karvonen, HM, Niskanen, LK & Sarkkinen, ES (2004) Mineral water fortified with folic acid, vitamins B6, B12, D and calcium improves folate status and decreases plasma homocysteine concentration in men and women. Eur J Clin Nutr 58, 376–385.CrossRefGoogle ScholarPubMed
Terpstra, AHM, Woodward, CJH & Sánchez-Muniz, FJ (1981) Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum. Anal Biochem 111, 149–157.CrossRefGoogle ScholarPubMed
Toussaint, C, Peuchant, E, Nguyen, BC, Jensen, R & Canellas, J (1986) Influence of calcic and magnesic sulphurous thermal water on the metabolism of lipoproteins in the rat. Arch Int Physiol Biochem 94, 65–76.Google Scholar
Wilhelm, MG & Cooper, AD (2003) Induction of atherosclerosis by human chylomicron remnants: a hypothesis. J Atheroscler Thromb 10, 132–139.CrossRefGoogle ScholarPubMed
Van Beek, AP, de Ruijter-Heijstek, FC, Erkelens, DW & de Bruin, TW (1999) Menopause is associated with reduced protection from postprandial lipemia. Arterioscler Thromb Vasc Biol 19, 2737–2741.CrossRefGoogle ScholarPubMed
Van Oostrom, AJ, Van Dijk, H, Verseyden, C et al. , (2004) Addition of glucose to an oral fat load reduces postprandial free fatty acids and prevents the postprandial increase in complement component. Am J Clin Nutr 79, 510–515.CrossRefGoogle Scholar
Volek, JS, Sharman, MJ, Gomez, AL, Scheet, TP & Kraemer, WJ (2003) An isoenergetic very low carbohydrate diet improves serum HDL-cholesterol and triacylglycerol concentration, the total cholesterol to HDL cholesterol ratio and postprandial lipemic responses compared with low fat diet in normal weight, normolipodemic women. Nutrition 133, 2756–2761.Google Scholar