Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-06T04:11:59.750Z Has data issue: false hasContentIssue false
  • English
  • Français

Role of vitamin E in the aetiology of phrynoderma (follicular hyperkeratosis) and its interrelationship with B-complex vitamins

Published online by Cambridge University Press:  09 March 2007

H. A. Nadiger
H. A. Nadiger
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Hyderabad – 500 007, India
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. A study was undertaken to investigate the role of vitamin E in the aetiology of phrynoderma (follicular hyperkeratosis). Fifty-six children with the disease and twenty-one normal children were investigated for this purpose.

2. Plasma vitamin E levels (mean±SE; mg/l) were found to be low in phrynoderma (3.7±0.19) in contrast with normal children (6.6±0.40) and therapy with a combination of vitamin E and B-complex brought about complete cure.

3. The increase in plasma vitamin E levels after the administration of vitamin E at a dose of 100 mg three times daily for 4 weeks was higher than that obtained when vitamin E at the same dose was administered together with vitamin B-complex for 4 weeks, suggesting an interaction between the two vitamins. Further studies are necessary to find out the exact nature of this interrelationship.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 44 , Issue 3 , November 1980 , pp. 211 - 214
Copyright
Copyright © The Nutrition Society 1980

References

REFERENCES

Achaya, K. T. (1978 a). Indian J. Nutr. Diet. 15, 120.Google Scholar
Achaya, K. T. (1978 b). Indian J. Nutr. Diet. 15, 149.Google Scholar
Achaya, K. T. (1978 c). Indian J. Nutr. Diet. 15, 181.Google Scholar
Bagchi, K., Halder, K. & Chowdhury, S. R. (1959). Am. J. clin. Nutr. 7, 251.CrossRefGoogle Scholar
Bhat, K. S. & Belavady, B. (1967). Am. J. clin. Nutr. 20, 386.CrossRefGoogle Scholar
Bieri, J. G. & Farrel, P. M. (1976). Vitams Horm. 34, 31.CrossRefGoogle Scholar
Day, P. L. & Dinning, J. S. (1956). Am. J. clin. Nutr. 4, 386.CrossRefGoogle Scholar
FAO (1977). Dietary Fats and Oils in Human Nutrition, p. 19, FAO, Rome.Google Scholar
Gopalan, C. (1947). Indian med. Gaz. 82, 16.Google Scholar
Green, J. (1962). Vitams Horm. 20, 485.CrossRefGoogle Scholar
Kayden, H. J., Ching-Kuang, C. & Bjornson, L. K. (1973). J. Lipid Res. 14, 533.CrossRefGoogle Scholar
Menon, P. S., Tulpule, P. G. & Patwardhan, V. N. (1950). Indian J. med. Res. 38, 173.Google Scholar
Scott, M. L. (1978). In The Fat-Soluble Vitamins, p. 133 [DeLuca, H. F., editor]. New York: Plenum Press.CrossRefGoogle Scholar
Srikantia, S. G. & Belavady, B. (1961). Indian J. med. Res. 49, 109.Google Scholar
Srikantia, S. G. & Pargaonkar, V. U. (1964). J. trop. Med. Hyg. 67, 295.Google Scholar
Young, J. M. Jr, Dinning, J. S. & Day, P. L. (1955). Proc. Soc. exp. Biol. Med. 89, 216.CrossRefGoogle Scholar