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Response to oral administration of pteroylmonoglutamic acid or pteroylpolyglutamate in newborn infants of low birth weight*

Published online by Cambridge University Press:  09 March 2007

Pamela D. Samuel
Affiliation:
The Clinical InvestiBation Unit, Glaxo Laboratories, Greenford, Middlesex
W. L. Burland
Affiliation:
The Clinical InvestiBation Unit, Glaxo Laboratories, Greenford, Middlesex
K. Simpson
Affiliation:
Paediatric Department, Leicester General Hospital, Leicester
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Abstract

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1. Newborn infants of low birth weight absorb both pteroylmonoglutamic acid and pteroylpolyglutamate.

2. There was a significant fall in serum folate concentrations during the first 14 d of life in these infants, but a daily supplement of 50 μg pteroylmonoglutamic acid or pteroylpolyglutamate was sufficient to prevent the development of subnormal serum folate concentrations.

Type
Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1973

References

Burland, W. L., Simpson, K. & Lord, J. (1971). Archs Dis. Childh, 46, 189.CrossRefGoogle Scholar
Butterworth, C. E. Jr, Santini, R. Jr & Frommeyer, W. B. Jr (1963). J. Clin Invest. 42, 1929.CrossRefGoogle Scholar
Ford, J. E. & Scott, K. J. (1968). J. Dairy Res. 35, 85.CrossRefGoogle Scholar
Hoffbrand, A. V., Newcombe, B. F. & Mollin, D. L. (1966). J. clin. Path. 19, 17.CrossRefGoogle Scholar
Hoffbrand, A. V., & Peters, T. J. (1969). Biochem. biophys. Acta 192, 479.CrossRefGoogle Scholar
Matoth, Y., Pinkas, A. & Sroka, C. (1965). Israel J. Med. Sci. 1, 730.Google Scholar
Matoth, Y., Pinkas, A., Zamir, R., Mooallem, F. & Grossowicz, N. (1964). Pediatrics, Springfield 33, 507.CrossRefGoogle Scholar
Perry, J. & Chanarin, I. (1968). Br. med. J. 4, 546.CrossRefGoogle Scholar
Roberts, P. M.Arrowsmith, D. E., Rau, S. M. & Monk-Jones, M. E. (1969). Archs Dis Childh. 44, 637.CrossRefGoogle Scholar
Shojania, A. M. & Gross, S. (1964). J. Pediat. 64, 323.CrossRefGoogle Scholar
Strelling, M. K., Blackledge, G. D., Goodall, H. B. & Walker, C. H. M. (1966). lancet i, 898.CrossRefGoogle Scholar
Sullivan, L. W., Luhby, A. L. & Streiff, R. R. (1966). Am. clin. Nutr. 18, 311.Google Scholar
Vanier, T. M. & Tyas, J. F. (1967). Archs Dis. Childh, 42, 57.CrossRefGoogle Scholar
Waters, A. H. & Mollin, D. L. (1961). J. clin. Path. 14, 335.CrossRefGoogle Scholar
WHO (1970). Tech, Rep. Ser. Wld Hlth Org. no. 452.Google Scholar