Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-23T16:35:11.235Z Has data issue: false hasContentIssue false
  • English
  • Français

Relations between plasma non-esterified fatty acid metabolism and body fat mobilization in primiparous lactating goats

Published online by Cambridge University Press:  09 March 2007

F. R. Dunshea ,
A. W. Bell  and
T. E. Trigg
F. R. Dunshea
Affiliation:
School of Agriculture, La Trobe University, Bundoora, Victoria 3083, Australia
A. W. Bell
Affiliation:
School of Agriculture, La Trobe University, Bundoora, Victoria 3083, Australia
T. E. Trigg
Affiliation:
Animal and Irrigated Pastures Research Institute, Kyabram, Victoria 3620, Australia
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

During early lactation ruminants can mobilize considerable amounts of body fat to maintain milk production. The aim of the present study was to evaluate the efficacy of tritiated water (TOH) and non-esterified fatty acid (NEFA) kinetics as means of monitoring adipose tissue fat mobilization in lactating goats. Body fat, as estimated by a two-pool model of TOH kinetics, and NEFA entry rate were measured in four primiparous goats at days 11, 37 and 72 post partum. Estimated body fat decreased by an average of 64 g/d between days 11 and 37 of lactation, tending to increase between days 37 and 72. Plasma NEFA concentrations and NEFA entry rate decreased as lactation advanced, being significantly lower at day 72 than at day 11 of lactation. Both plasma concentrations of NEFA and NEFA entry rate were negatively correlated with calculated energy balance. Plasma NEFA concentrations and NEFA entry rate at days 11 and 37 of lactation were positively related to average body fat losses over the subsequent stage of lactation. These results demonstrate that NEFA kinetics reflect fat mobilization in primiparous lactating goats, particularly during negative energy balance.

Keywords

Fat mobilizationLactationNon-esterified fatty acidsGoat
Type
Research Article
Information
British Journal of Nutrition , Volume 62 , Issue 1 , July 1989 , pp. 51 - 61
Copyright
Copyright © The Nutrition Society 1989

References

REFERENCES

Agricultural Research Council (1980). The Nutrient Requirements of Ruminant Livestock. Slough: Commonwealth Agriculture Bureaux.Google Scholar
Anderson, L.E. & MacClure, W.O. (1973). An improved scintillation cocktail of high solubilizing power. Analytical Biochemistry 51, 173–179.CrossRefGoogle ScholarPubMed
Annison, E.F., Brown, R.E., Leng, R.A., Lindsay, D.B. & West, C.E. (1967). Rates of entry and oxidation of acetate, glucose, D(–)-β-hydroxybutyrate, palmitate, oleate and stearate, and rates of production and oxidation of propionate and butyrate in fed and starved sheep. Biochemical Journal 104, 135–147.CrossRefGoogle ScholarPubMed
Armstrong, D.G. & Blaxter, K.L. (1965). Effects of acetic and propionic acids on energy retention and milk secretion in goats. In Energy Metabolism, pp. 59–72 [Blaxter, K.L., editor]. London: Academic Press.Google Scholar
Bartle, S.J., Preston, R.L. & Males, J.R. (1983). Evaluation of plasma free fatty acids as indicators of energy status in lactating beef cows. Nutrition Reports International 28, 345–354.Google Scholar
Bauman, D.E. & Currie, W.B. (1980). Partitioning of nutrients during pregnancy and lactation: a review of mechanisms involving homeostasis and homeorhesis. Journal of Dairy Science 63, 1514–1529.CrossRefGoogle ScholarPubMed
Bauman, D.E., Peel, C.J., Steinhour, W.D., Reynolds, P.J., Tyrrell, H.F., Brown, A.C.G. & Haaland, G.L. (1988). Effect of bovine somatotropin on metabolism of lactating dairy cows: influence on rates of irreversible loss and oxidation of glucose and nonesterified fatty acids. Journal of Nutrition 118, 1031–1047.CrossRefGoogle ScholarPubMed
Bell, A.W. & Thompson, G.E. (1979). Free fatty acid oxidation in bovine muscle in vivo: effects of cold exposure and feeding. American Journal of Physiology 237, E309–E315.Google ScholarPubMed
Bines, J.A. (1979). Voluntary feed intake. In Feeding Strategies for the High Yielding Dairy Cow, pp. 23–28 [Broster, W.H. and Swan, H., editors]. London: Granada Press.Google Scholar
Byers, F.M. (1979). Measurement of protein and fat accretion in growing beef cattle through isotope dilution procedures. In Ohio Beef Cattle Research Progress Report, Series 79–1, pp. 36–47. Wooster, Ohio: Ohio Agricultural Research Development Center.Google Scholar
Chilliard, Y., Robelin, J. & Remond, B. (1984). In vivo estimation of body lipid mobilization and reconstitution in dairy cattle. Canadian Journal of Animal Science 64, Suppl., 236–237.CrossRefGoogle Scholar
Chilliard, Y., Sauvant, D., Morand-Fehr, P. & Delouis, C. (1987). Relations entre le bilan énergétique et l'activité métabolique du tissu de la chèvre au cours de la première moitié de la lactation. Reproduction, Nutrition, Développement 27, 307–308.CrossRefGoogle Scholar
Corbett, J.L., Farrell, D.J., Leng, R.A., McClymont, G.L. & Young, B.A. (1971). Determination of the energy expenditure of penned and grazing sheep from estimates of carbon dioxide entry rate. British Journal of Nutrition 26, 277–291.CrossRefGoogle ScholarPubMed
Cowan, R.T., Robinson, J.J., McHattie, I. & Fraser, C. (1980). The prediction of body composition in live ewes in early lactation from live weight and estimates of gut contents and total body water. Journal of Agricultural Science, Cambridge 95, 515–522.CrossRefGoogle Scholar
Cowan, R.T., Robinson, J.J., McHattie, I. & Pennie, K. (1981). Effects of protein concentration in the diet on milk yield, change in body composition and the efficiency of utilization of body tissues for milk production in ewes. Animal Production 33, 111–120.Google Scholar
Downes, A.M. & McDonald, I.W. (1964). The chromium-51 complex of ethylene-diamine-tetra-acetic acid as a soluble rumen marker. British Journal of Nutrition 18, 153–162.CrossRefGoogle Scholar
Dunshea, F.R. (1987). Use of labile tissue reserves during chronic undernutrition or early lactation in dairy goats. PhD Thesis, La Trobe University, Bundoora, Australia.Google Scholar
Dunshea, F.R. & Bell, A.W. (1987). Non-esterified fatty acid (NEFA) reesterification and fat mobilization in goats during early lactation. Journal of Dairy Science 70, Suppl., P10.Google Scholar
Dunshea, F.R., Bell, A.W., Chandler, K.D. & Trigg, T.E. (1988a). A two-pool model of tritiated water kinetics to predict body composition in unfasted lactating goats. Animal Production 47, 435–445.Google Scholar
Dunshea, F.R., Bell, A.W. & Trigg, T.E. (1988b). Relations between plasma non-esterified fatty acid metabolism and body tissue mobilization during chronic undernutrition in goats. British Journal of Nutrition 60, 633–644.CrossRefGoogle Scholar
Flatt, W.P., Moore, L.P., Hooven, N.W. & Plowman, R.D. (1965). Energy metabolism studies with a high-producing dairy cow. Journal of Dairy Science 48, 797 Abstr.Google Scholar
Foot, J.Z. & Greenhalgh, J.F.D. (1970). The use of deuterium oxide space to determine the amount of body fat in pregnant Blackface ewes. British Journal of Nutrition 24, 815–825.CrossRefGoogle ScholarPubMed
Foot, J.Z., Heazlewood, P.G. & Joseph, K. (1984). Partitioning of energy in young lactating sheep. In Reproduction in Sheep, pp. 269–271 [Lindsay, D.R. and Pearce, D.T., editors]. Canberra: Australian Academy of Science.Google Scholar
Hecker, J.F. (1969). A simple rapid method for inserting rumen cannulae in sheep. Australian Veterinary Journal 45, 293, 294.CrossRefGoogle ScholarPubMed
Hecker, J.F. (1974). Experimental Surgery on Small Ruminants. London: Butterworths.Google Scholar
Holmes, J.H.G. & Lambourne, L.J. (1970). The relation between plasma free fatty acid concentration and the digestible energy intake of cattle. Research in Veterinary Science 11, 27–36.CrossRefGoogle ScholarPubMed
Konig, B.A., Parker, D.S. & Oldham, J.D. (1979). Acetate and palmitate kinetics in lactating dairy cows. Annales de Recherches Vétérinaires 10, 368–370.Google ScholarPubMed
Lindsay, D.B. (1978). The effect of feeding pattern and sampling procedure on blood parameters. In The Use of Blood Metabolites in Animal Production, pp. 99–120 [Lister, D., editor]. Thames Ditton: British Society of Animal Production.Google Scholar
Lindsay, D.B. & Leat, W.N.F. (1977). Oxidation and metabolism of linoleic acid in fed and fasted sheep. Journal of Agricultural Science, Cambridge 89, 215–221.CrossRefGoogle Scholar
Martin, R.A. & Ehle, F.R. (1986). Body composition of lactating and dry Holstein cows estimated by deuterium dilution. Journal of Dairy Science 69, 88–98.CrossRefGoogle ScholarPubMed
Ministry of Agriculture, Fisheries and Food (1975). Energy Allowances and Feeding Systems for Ruminants. Technical Bulletin no. 33. London: H.M. Stationery Office.Google Scholar
Moe, P.W., Tyrrell, H.F. & Flatt, W.P. (1971). Energetics of body tissue mobilization. Journal of Dairy Science 54, 548–553.CrossRefGoogle ScholarPubMed
Panaretto, B.A. & Till, A.R. (1963). Body composition in vivo. II. The composition of mature goats and its relationship to the antipyrine, tritiated water, and N-acetyl-4-aminoantipyrine spaces. Australian Journal of Agricultural Research 14, 926–943.CrossRefGoogle Scholar
Parker, B.N.J. & Lewis, G. (1978). In The Use of Blood Metabolites in Animal Production, pp. 121–132 [Lister, D., editor]. Thames Ditton: British Society of Animal Production.Google Scholar
Pethick, D.W., Lindsay, D.B., Barker, P.J. & Northrop, A.J. (1983). The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. British Journal of Nutrition 49, 129–143.CrossRefGoogle Scholar
Reid, R.L. & Hinks, N.T. (1962). Studies on the carbohydrate metabolism of sheep. XVIII. The metabolism of glucose, free fatty acids, and ketones after feeding and during fasting or undernourishment of non-pregnant, pregnant and lactating ewes. Australian Journal of Agricultural Research 13, 1124–1136.CrossRefGoogle Scholar
Ross, G.J.S. (1980). MLP: Maximum Likelihood Program (Version 3.06), Rothamsted, Herts.: Rothamsted Experimental Station.Google Scholar
Russel, A.J.F. & Wright, I.A. (1983). The use of blood metabolites in the determination of energy status in beef cows. Animal Production 37, 335–343.Google Scholar
Ryan, T.A. Jr, Joiner, B.L. & Ryan, B.F. (1985). Minitab: Version 5.1 Massachusetts: Duxbury Press.Google Scholar
SAS (1982). SAS User's Guide: Statistics. Cary, NC: SAS Institute, Inc.Google Scholar
Searle, T.W. (1970). Body composition in lambs and young sheep and its prediction in vivo from tritiated water space and body weight. Journal of Agricultural Science, Cambridge 74, 357–362.CrossRefGoogle Scholar
Shipley, R.A. & Clark, R.E. (1972). Tracer Methods for in vivo Kinetics. New York: Academic Press.Google Scholar
Trigg, T.E. & Topps, J.H. (1981). Composition of body-weight change during lactation in Hereford x British Friesian cows. Journal of Agricultural Science, Cambridge 97, 147–157.CrossRefGoogle Scholar