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The relation between alcohol intake and physical activity and the fatty acids 14: 0, 15: 0 and 17: 0 in serum phospholipids and adipose tissue used as markers for dairy fat intake

Published online by Cambridge University Press:  08 March 2007

M. Rosell ,
G. Johansson ,
L. Berglund ,
B. Vessby ,
U. de Faire  and
M.-L. Hellénius
M. Rosell*
Affiliation:
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
G. Johansson
Affiliation:
Department of Food and Nutrition, University of Umeå, Umeå, Sweden
L. Berglund
Affiliation:
UCR Uppsala Clinical Research Center, University of Uppsala, Uppsala, Sweden
B. Vessby
Affiliation:
Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden
U. de Faire
Affiliation:
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden Center for Clinical Cardiovascular Research, Department of Cardiology, Karolinska Hospital, Stockholm, Sweden
M.-L. Hellénius
Affiliation:
Center for Clinical Cardiovascular Research, Department of Cardiology, Karolinska Hospital, Stockholm, Sweden Department of Family Medicine, Karolinska Institutet, Stockholm, Sweden
*
*Corresponding author: Dr Magdalena Rosell, fax +44 (0) 1865 310 545, email [email protected]
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Abstract

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The relative contents of the fatty acids 14: 0, 15: 0 and 17: 0 in serum and adipose tissue may be used as biological markers of dairy fat intake. However, the determinants of these fatty acids are not fully understood. This study investigates the relationship between these fatty acids and the intake of macronutrients and physical activity in a cross-sectional study of 301 healthy men aged 61–64 years. Dietary intake was assessed using a pre-coded 7 d food record, and physical activity during the previous year was recorded in an interview. Under-reporters of energy intake were identified by the Goldberg cut-off. Fatty acid composition was determined in serum phospholipids (PL) and subcutaneous adipose tissue (AT) from the upper buttock. The relative content of each of 14: 0, 15: 0 and 17: 0 in PL and AT was positively associated with the intake of dairy fat. In addition, all three fatty acids were inversely correlated with alcohol intake, R ranging from −0·28 to −0·53 (P<0·001). The results were not markedly affected when under-reporters (n 88) were excluded from the analyses. In both PL and AT, the relative content of the fatty acids was approximately 5% higher in a group of high physical activity compared with a group of low physical activity, although significant trends were only seen for 14: 0 in PL and 17: 0 in AT. The findings suggest that adjustments should be made for alcohol intake when the fatty acids 14: 0, 15: 0 and 17: 0 are applied as markers for dairy fat intake.

Keywords

Biological markersFatty acidsDairy fatAlcoholPhysical activity
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 1 , January 2005 , pp. 115 - 121
Copyright
Copyright © The Nutrition Society 2005

References

Andersson, A, Sjodin, A, Olsson, R & Vessby, B (1998) Effects of physical exercise on phospholipid fatty acid composition in skeletal muscle. Am J Physiol 274, E432–E438.Google ScholarPubMed
Arab, L (2003) Biomarkers of fat and fatty acid intake. J Nutr 133, S925–S932.CrossRefGoogle ScholarPubMed
Becker, W (1994) Food habits and nutrient intake in Sweden 1989 [in Swedish]. Uppsala, Sweden: National Food Administration.Google Scholar
Beyen, AC & Katan, MB (1985) Rapid sampling and long-term storage of subcutaneous adipose tissue biopsies for determination of fatty acid composition. Am J Clin Nutr 42, 317–322.CrossRefGoogle Scholar
Bingham, SA, Cassidy, A & Cole, TJ, et al. (1995) Validation of weighed food records and other methods of dietary assessment using the 24 h urine nitrogen technique and other biological markers. Br J Nutr 73, 531–550.CrossRefGoogle ScholarPubMed
Black, AE (2000a) Critical evaluation of energy intake using the Goldberg cut-off for energy intake:basal metabolic rate. A practical guide to its calculation, use and limitations. Int J Obes 24, 1119–1130CrossRefGoogle Scholar
Black, AE (2000b) The sensitivity and specificity of the Goldberg cut-off for EI:BMR for identifying diet reports of poor validity. Eur J Clin Nutr 54, 395–404CrossRefGoogle ScholarPubMed
Black, AE, Prentice, AM, Goldberg, GR, Jebb, SA, Bingham, SA, Livingstone, MBE & Coward, WA (1993) Measurements for total energy expenditure provide insights into the validity of dietary measurements of energy intake. J Am Diet Assoc 93, 572–579CrossRefGoogle ScholarPubMed
Bolton-Smith, C, Woodward, M & Tavendale, R (1997) Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. Eur J Clin Nutr 51, 619–624CrossRefGoogle ScholarPubMed
Department of HealthDepartment of Health (1991) Dietary Reference Values for Food Energy and Nutrients for the United Kingdom Report on Health and Social Subjects. London: HSMO.Google Scholar
Goris, AHC, Westerterp-Plantenga, MS & Westerterp, KR (2000) Undereating and underrecording of habitual food intake in obese men: selective under-reporting of fat intake. Am J Clin Nutr 71, 130–134CrossRefGoogle Scholar
Halliwell, KJ, Fielding, BA, Samra, JS & Humphreys, SM (1996) Release of individual fatty acids from human adipose tissue in vivo after an overnight fast. J Lipid Res 37, 1842–1848CrossRefGoogle ScholarPubMed
Hannuksela, ML, Liisanantt, MK & Savolainen, MJ (2002) Effect of alcohol on lipids and lipoproteins in relation to atherosclerosis. Crit Rev Clin Lab Sci 39, 225–283CrossRefGoogle ScholarPubMed
Lafay, L, Mennen, L, Basdevant, A, Charles, MA, Borys, JM, Eschwege, E & Romon, M (2000) Does energy intake under-reporting involve all kinds of food or only specific food items? Results from the Fleurbaix Laventie Ville Sante (FLVS) study. Int J Obes 24, 1500–1506Google ScholarPubMed
Macdiarmid, JI, Vail, A, Cade, JE & Blundell, JE (1998) The sugar-fat relationship revised: difference in consumption between men and women of varying BMI. Int J Obes 22, 1053–1061CrossRefGoogle Scholar
Mann, JI (2002) Diet and risk of coronary heart disease and type 2 diabetes. Lancet 360, 783–789CrossRefGoogle ScholarPubMed
Nikkari, T, Luukkainen, P, Pietinen, P & Puska, P (1995) Fatty acid composition of serum lipid fractions in relation to gender and quality of dietary fat. Ann Med 27, 491–498CrossRefGoogle ScholarPubMed
Pfeuffer, M & Schrezenmeir, J (2000) Bioactive substances in milk with properties decreasing risk of cardiovascular diseases. Br J Nutr 85 Suppl. 1S155–S159CrossRefGoogle Scholar
Poppitt, SD, Swann, D, Black, AE & Prentice, AM (1998) Assessment of selective under-reporting of food intake by both obese and non-obese women in a metabolic facility. Int J Obes 22, 303–331CrossRefGoogle Scholar
Pryer, AJ, Vrijheid, M, Nochols, R, Kiggins, M & Elliott, P (1997) Who are the ‘low engery reporters’ in the dietary and nuritional survey of British adults? Int J Epidemiol 26, 146–154CrossRefGoogle Scholar
Raclot, T, Langin, D, Lafontan, M & Groscolas, R (1997) Selective release of human adipocyte fatty acids according to molecular structure. Biochem J 324, 911–915CrossRefGoogle ScholarPubMed
Rosell, M, Hellenius, M-L, de Faire, U, Berglund, L, Gustafsson, I-B & Johansson, G (2003b) The contribution of a manually coded part in a optically readable, precoded 7-day food record to the intakes of energy, nutrients and foods. Scand J Nutr 47, 123–131CrossRefGoogle Scholar
Rosell, MS, Hellenius, M-LB, de Faire, U & Johansson, GK (2003a) The associations between diet and the metabolic syndrome vary with the validity of the dietary data. Am J Clin Nutr 78, 84–90CrossRefGoogle Scholar
Rosell, M, Johansson, G, Berglund, L, Vessby, B, de Faire, U & Hellenius, M-L (2004) Associations between the intake of dairy fat and calcium and abdominal obesity Int J Obes(in the press).Google Scholar
Sutherland, W, Woodhouse, S & Heyworth, M (1981) Physical training and adipose tissue fatty acid composition in men. Metabolism 30, 839–844CrossRefGoogle ScholarPubMed
Vessby, B (2000) Dietary fat and insulin action in humans. Br J Nutr 83 Suppl. 1S91–S96CrossRefGoogle ScholarPubMed
Wolk, A, Furuheim, M & Vessby, B (2001) Fatty acid composition of adipose tissue and serum lipids are valid biological markers of dairy fat intake in men. J Nutr 131, 828–833CrossRefGoogle ScholarPubMed
Wolk, A, Vessby, B, Ljung, H & Barrefors, P (1998) Evaluation of a biological marker of dairy fat intake. Am J Clin Nutr 68, 291–295Google ScholarPubMed
Yli-Jama, P, Haugen, TS, Rebnord, HM, Ringstad, J & Pedersen, JI (2001) Selective mobilisation of fatty acids from human adipose tissue. Eur J Intern Med 12, 107–115CrossRefGoogle ScholarPubMed