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Protein utilization during energy undernutrition in sheep sustained by intragastric infusion

Effect of body fatness on the protein metabolism of energy restricted sheep

Published online by Cambridge University Press:  09 March 2007

S. A. Chowdhury ,
E. R. Ørskovit ,
F. D. DeB. Hovell ,
J. R. Scalfe  and
G. Mollison
S. A. Chowdhury
Affiliation:
Rowett Research Institute, Bucksbun, Aberdeen AB21 9SB
E. R. Ørskovit
Affiliation:
Rowett Research Institute, Bucksbun, Aberdeen AB21 9SB
F. D. DeB. Hovell
Affiliation:
Rowett Research Institute, Bucksbun, Aberdeen AB21 9SB
J. R. Scalfe
Affiliation:
School of Agriculture, University of Aberdeen, 581 King Street, Aberdeen AB9 1UD
G. Mollison
Affiliation:
Rowett Research Institute, Bucksbun, Aberdeen AB21 9SB
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Abstract

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The effect of body fat content on the protein metabolism of energy-restricted sheep has been studied in two experiments. In the first experiment, six Suffolk-cross wether sheep, three weighing about 39 kg and three of about 61 kg, were given progressively increasing amounts of casein-N from 0 to 3000 mg N/kg metabolic body weight (W0·75) daily with constant energy, 91 kJ/kg W0·75 daily, from a high-propionic acid mixture of volatile fatty acids (VFA). In the second experiment, two lean and two fat sheep of similar body weights were given progressively increasing amounts of casein with the same VFA mixture. All the animals attained a positive N balance when they were in negative energy balance. N balance was not affected by body fatness of the magnitude studied, although lean animals utilized increasing levels of standard VFA (acetate-propionate-butyrate 65:25:10, molar proportions) infusion for N accretion more efficiently than fat animals. Endogenous energy was utilized for protein accretion with an efficiency of 0·56. Supply of glucogenic VFA equivalent to 28 mmol glucose/kg W0·75 reduced fasting N excretion by 39%. Fasting heat production decreased from 335 to 300 kJ/kg W0·75 with the infusion of casein and glucogenic VFA. It is argued that fasting induces additional heat losses due to raised protein metabolism and is unsuited as a baseline for dietary assessment.

Keywords

Body compositionEnergy restrictionProtein utilizationFasting metabolism
Type
Animal Nutrition
Information
British Journal of Nutrition , Volume 78 , Issue 2 , August 1997 , pp. 273 - 282
Copyright
Copyright © The Nutrition Society 1997

References

REFERENCES

Agricultural Research Council (1980). The Nutrient Requirements of Ruminant Livestock. Slough: Commonwealth Agricultural Bureaux.Google Scholar
Alliston, J. C. (1983). Evaluation of carcass quality in the live animal. In Sheep Production, pp. 75–91 [Haresign, W., editor]. London: Butterworths.Google Scholar
Asplund, J. M., Ørskov, E. R., Hovell, F. D. DeB. & MacLeod, N. A. (1985). The effect of intragastric infusion of glucose, lipid or acetate on fasting nitrogen excretion and blood metabolites in sheep. British Journal of Nutrition 54, 189–195.CrossRefGoogle ScholarPubMed
Bergman, E. N. (1973). Glucose metabolism in ruminant as related to hypoglycaemia and ketosis. Cornell Veterinarian 63, 341–382.Google Scholar
Bergman, E. N. (1983). The pool of cellular nutrients: Glucose. In Dynamic Biochemistry of Animal Production. World Animal Science, A, Basic Information, vol. 3, pp. 173–196 [Riis, P. M., editor]. Amsterdam: Elsevier.Google Scholar
Blaxter, K. L. (1989). Energy Metabolism in Animals and Man. Cambridge: Cambridge University Press.Google Scholar
Brockway, J. M. (1987). Influence of activity. Rowett Research Institute Report. Aberdeen: Rowett Research Institute.Google Scholar
Chowdhury, S. A. (1992). Protein utilization during energy undernutrition in sheep. PhD Thesis, University of Aberdeen.Google Scholar
Chowdhury, S. A., Ørskov, E. R., Hovell, F. D. DeB., Scaife, J. R. & Mollison, G. (1997). Protein utilization during energy undernutrition in sheep sustained by intragastric infusion; effects of protein infusion level, with or without sub-maintenance amounts of energy from volatile fatty acids, on energy and protein metabolism. British Journal of Nutrition 77, 565–576.CrossRefGoogle ScholarPubMed
Hovell, F. D. DeB. & MacPherson, R. M. (1977). Thin sows. 1. Observations on the fecundity of sows when underfed for several parities. Journal of Agricultural Science, Cambridge 89, 513–522.CrossRefGoogle Scholar
Hovell, F. D. DeB., Ørskov, E. R. & MacLeod, N. A. (1983). The effect of change in the amount of energy infused as volatile fatty acids on the nitrogen retention and creatinine excretion of lambs absolutely nourished by intragastric infusion. British Journal of Nutrition 50, 331–343.CrossRefGoogle Scholar
Hovell, F. D. DeB., Ørskov, E. R., Kyle, D. J. & MacLeod, N. A. (1987). Undernutrition in sheep. Nitrogen retention by nitrogen depleted sheep. British Journal of Nutrition 57, 77–88.CrossRefGoogle ScholarPubMed
Humphries, W. R., Morrice, P. C. & Bremner, I. (1988). A convenient method for the treatment of chronic copper poisoning in sheep using subcutaneous ammonium tetrathiomolybdate. Veterinary Record 123, 51–53.CrossRefGoogle ScholarPubMed
Iason, G. R., Mantecon, A. R., Milne, J. A., Sim, D. A. & White, I. R. (1992). The effect of pattern of food supply on performance, compensatory growth and carcass composition of Beulah Welsh Mountain sheep. Animal Production 54, 235–241.Google Scholar
Krebs, H. A. (1964). The metabolic fate of amino acids. In Mammalian Protein Metabolism, pp. 125–176 [Munro, H. N. and Allison, J. B. editors]. New York: Academic Press.CrossRefGoogle Scholar
Ku Vera, J. C. (1983). Mechanisms of the nitrogen-sparing effect of glucose in fasting sheep. MSc Thesis, University of Aberdeen.Google Scholar
Ku Vera, J. C. (1988). Energy and nitrogen metabolism in cattle nourished by intragastric infusion of nutrients. PhD Thesis, University of Aberdeen.Google Scholar
Ku Vera, J. C., MacLeod, N. A. & ØBrskov, E. R. (1989). Energy exchanges of cattle nourished by intragastric infusion. In Energy Metabolism of Farm Animals. European Association of Animal Production Publication, pp. 271–274 [van der Honing, H. and Close, W. H., editors]. Wageningen: Pudoc.Google Scholar
Larvor, P. (1983). The pool of cellular nutrients: Minerals. In Dynamic Biochemistry ofAnirnal Production, pp. 281–317 [Riis, P. M., editor]. Amsterdam: Elsevier Science Publisher Ltd.Google Scholar
Lawes Agricultural Trust (1990). Gensrat V, Murk 4–03. Harpenden, Herts: Rothamsted Experimental Station.Google Scholar
Leng, R. A. (1970). Glucose synthesis in ruminants. Advances in Veterinary Science and Comparative Medicine 14, 209–260.Google ScholarPubMed
Lobley, G. E. (1991). Some interaction between protein and energy in ruminant metabolism. In Protein Metabolism and Nutrition. European Association of Animal Production Publication, pp. 66–79 [Eggum, B. O., Boisen, S., Borsting, C., Danfaer, A. and Huelplund, T. H., editors]. Foulum, Denmark: National Institute for Animal Science Research.Google Scholar
O'Donovan, P. B. (1984). Compensatory growth in cattle and sheep. Nutrition Abstracts and Reviews 54, 389–410.Google Scholar
Ørskov, E. R., McDonald, I., Fraser, C. & Corse, E. L. (1976). Nutrition of the early weaned lambs. IV. Effect on growth rate, food utilization and body composition at different live weights. Journal of Agricultural Science, Cambridge 86, 411–423.CrossRefGoogle Scholar
Ørskov, E. R. & Ryle, M. (1990). Energy Nutrition in Ruminants, pp. 129–131. London and New York: Elsevier Science Publisher Ltd.Google Scholar
Ryan, W. J. (1990). Compensatory growth in cattle and sheep. Nutrition Abstracts and Reviews 60, 653–664.Google Scholar