Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-19T08:48:16.704Z Has data issue: false hasContentIssue false
  • English
  • Français

Protein metabolism in growing lambs given fresh ryegrass (Lolium perenne) – clover (Trifolium repens) pasture ad lib

2. Endocrine changes, glucose production, and their relationship to protein deposition and the partition of absorbed nutrients

Published online by Cambridge University Press:  24 July 2007

T. N. Barry ,
T. R. Manley ,
Carolyne Redekopp ,
S. R. Davis ,
R. J. Fairclough  and
K. R. Lapwood
T. N. Barry
Affiliation:
Invermay Agricultural Research Centre, Private Bag, Mosgiel, New Zealand
T. R. Manley
Affiliation:
Invermay Agricultural Research Centre, Private Bag, Mosgiel, New Zealand
Carolyne Redekopp
Affiliation:
Department of Endocrinology, Princess Margaret Hospital, Christchurch, New Zealand
S. R. Davis
Affiliation:
Ruakura Research Centre, Hamilton, New Zealand
R. J. Fairclough
Affiliation:
Ruakura Research Centre, Hamilton, New Zealand
K. R. Lapwood
Affiliation:
Massey University, Palmerston North, New Zealand
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Glucose metabolism and changes in the concentrations of several hormones in jugular plasma were measured in growing lambs fed on fresh pasture ad lib. One group of lambs acted as control while the second received a continuous abomasal infusion supplying 44 g sodium caseinate + 0·5 g L-methionine/d.

2. Hormone concentrations were determined by radioimmunoassay procedures and glucose irreversible loss measured from continuous infusion of D-[U–14C]glucose.

3. Protein infusion increased plasma concentrations of insulin, glucagon and thyroxine (T4), depressed those of growth hormone, prolactin and somatostatin and had no effect on triiodothyronine (T3) concentrations. Cortisol concentrations also tended to be slightly higher in the plasma of protein-infused lambs.

4. Increases in herbage intake within the ad lib. range were associated with increases in plasma insulin and glucagon concentrations and decreases in growth hormone concentration, and it is suggested that these effects could be mediated in part by the accompanying increases in protein absorption from the intestines. The T4:T3 value also decreased with increasing herbage intake, and it is suggested this was due to conversion of T4 to T3.

5. After correction by covariance to equal herbage intake, rates of irreversible glucose loss for control and protein-infused lambs were 9·2 and 10·0 mg/min per kg body-weight0·75. It was calculated that respectively 0·12 and 0·19 of the total glucose production in control and protein-infused lambs could be accounted for by net synthesis from protein.

6. It was concluded that changes in the circulating concentration of several hormones in protein-infused compared with control lambs were likely to have been implicated in protein deposition forming a greater proportion of energy retention in the infused lambs (0·41 v. 0·27).

Type
Research Article
Information
British Journal of Nutrition , Volume 47 , Issue 2 , March 1982 , pp. 319 - 329
Copyright
Copyright © The Nutrition Society 1982

References

Albano, J. D. M., Ekins, R. P., Marity, G. & Turner, R. C. (1972). Acta Endocr. 70, 487.Google Scholar
Arimura, A., Lundquick, G., Rothan, T., Chang, R., Fernandez Durango, R., Edde, R., Gog, D. H., Meyers, C. & Schally, A. V. (1978). Metabolism 27, 1139.Google Scholar
Barry, T. N. (1981 a). Br. J. Nutr. 46, 521.Google Scholar
Barry, T. N. (1981 b). N.Z. Jl agric. Res. 23, 427.CrossRefGoogle Scholar
Bassett, J. M. (1975). In Digestion and Metabolism in the Ruminant. Proceedings 4th International Symposium on Ruminant Physiology, p. 383 [McDonald, I. W. and Warner, A. C. I., editors]. Armidale: University of New England Publishing Unit.Google Scholar
Bassett, J. M., Weston, R. H. & Hogan, J. P. (1971). Aust. J. biol. Sci. 24, 321.Google Scholar
Bines, J. A., Hart, I. C. & Morant, S. V. (1980). Br. J. Nutr. 43, 179.Google Scholar
Blair, A. & Segal, S. (1960). J. Lab. clin. Med 55, 959.Google Scholar
Clark, J. H., Spires, H. R., Derrig, R. G. & Bennink, M. R. (1977). J. Nutr. 107, 631.Google Scholar
Coop, I. E. (1953). J. agric. Sci., Camb 43, 456.Google Scholar
Fairclough, R. J. & Liggins, G. C. (1975). J. Endocr. 67, 333.CrossRefGoogle Scholar
Ferguson, K. A., Wallace, A. L. C. & Lindner, H. R. (1965). In Biology of the skin and hair growth, p. 655 [Lyne, A. G. and Short, B. F., editors]. Sydney: Angus & Robertson.Google Scholar
Hart, I. C., Bines, J. A. & Morant, S. V. (1979). J. Dairy Sci. 62, 270.Google Scholar
Hart, I. C., Bines, J. A., Morant, S. V., Napper, D. J., Danby, K. A. M. & Black, L. A. (1978 a). A. Rep. natn. Inst. Res. Dairy p. 106.Google Scholar
Hart, I. C., Bines, J. A., Morant, S. V. & Ridley, J. L. (1978 b). J. Endocr. 77, 333.Google Scholar
Larsson, L. I., Goltermann, N., Magestres, L., Rehfeld, J. F. & Schwartz, T. W. (1979). Science N. Y. 205, 1393.Google Scholar
Lindsay, D. B. (1980). Proc. Nutr. Soc. 39, 53.Google Scholar
Machlin, L. J. (1973). J. Dairy Sci. 56, 575.CrossRefGoogle Scholar
Morley, J. EGarvin, T. J., Pekary, E. & Hersham, J. M. (1977). Biochem. Biophys. Res. Commun. 79, 314.Google Scholar
Panaretto, B. A. (1979). In Physiological & Environmental Limitations to Wool Growth, p. 327 [Black, J. L. and Reis, P. J., editors]. Armidale: University of New England Publishing Unit.Google Scholar
Saddler, W. A. & Brownlie, B. E. W. (1975). N.Z. med. J. 81, 328.Google Scholar
Swan, H. (1976). In Principles of Cattle Production, p. 85 [Swan, H. and Broster, W. H., editors]. London: Butterworths.Google Scholar
Trenkle, A. H. (1971). J. Nutr. 101, 1099.CrossRefGoogle Scholar
Trenkle, A. H. (1976). J. Anim. Sci. 43, 1035.Google Scholar
Trenkle, A. H. (1980). In Digestive Physiology and Metabolism in Ruminants. Proceedings 5th International Symposium on Ruminant Physiology, p. 505 [Ruchenbusch, Y. and Thivend, P., editors]. Lancaster: MTP Press.Google Scholar
Unger, R. M., Aguilar-Paroda, E., Muller, W. A. & Eisentrout, A. M. (1970). J. clin. Invest. 49, 837.Google Scholar
Wallace, A. L. C. (1979). In Physiological & Environmental Limitations to Wool Growth, p. 257 [Black, J. L. and Reis, P. J., editors]. Armidale: University of New England Publishing Unit.Google Scholar