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Pork meat increases iron absorption from a 5-day fully controlled diet when compared to a vegetarian diet with similar vitamin C and phytic acid content

Published online by Cambridge University Press:  08 March 2007

Mette Bach Kristensen ,
Ole Hels ,
Catrine Morberg ,
Jens Marving ,
Susanne Bügel  and
Inge Tetens
Mette Bach Kristensen*
Affiliation:
Department of Human Nutrition, Centre for Advanced Food Studies (LMC), The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
Ole Hels
Affiliation:
Department of Human Nutrition, Centre for Advanced Food Studies (LMC), The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
Catrine Morberg
Affiliation:
Department of Human Nutrition, Centre for Advanced Food Studies (LMC), The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
Jens Marving
Affiliation:
Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Denmark
Susanne Bügel
Affiliation:
Department of Human Nutrition, Centre for Advanced Food Studies (LMC), The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
Inge Tetens
Affiliation:
Department of Human Nutrition, Centre for Advanced Food Studies (LMC), The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
*
*Corresponding author: Dr M. Bach Kristensen, fax +45 35282469, email [email protected]
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Abstract

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Meat increases absorption of non-haem iron in single-meal studies. The aim of the present study was to investigate, over a 5 d period, the potential increasing effect of consumption of pork meat in a whole diet on the fractional absorption of non-haem iron and the total absorption of iron, when compared to a vegetarian diet. A randomised cross-over design with 3×5 d whole-diet periods with diets containing Danish-produced meat, Polish-produced meat or a vegetarian diet was conducted. Nineteen healthy female subjects completed the study. All main meals in the meat diets contained 60 g of pork meat and all diets had high phytic acid content (1250 μmol/d). All main meals were extrinsically labelled with the radioactive isotope 59Fe and absorption of iron was measured in a whole body counter. The non-haem iron absorption from the Danish meat diet was significantly higher compared to the vegetarian diet (P=0·031). The mean fractional absorption of non-haem iron was 7·9 (se1·1), 6·8 (se 1·0) and 5·3 (se 0·6) % for the Danish and Polish meat diets and vegetarian diet, respectively. Total absorption of iron was higher for both meat diets compared to the vegetarian diet (Danish meat diet: P=0·006, Polish meat diet: P=0·003). The absorption ratios of the present study were well in accordance with absorption ratios estimated using algorithms on iron bioavailability. Neither the meat diets nor the vegetarian diets fulfilled the estimated daily requirements of absorbed iron in spite of a meat intake of 180 g/d in the meat diets.

Keywords

Fe59Whole body countingBioavailabilityRadioisotopesWomen
Type
Research Article
Information
British Journal of Nutrition , Volume 94 , Issue 1 , July 2005 , pp. 78 - 83
Copyright
Copyright © The Nutrition Society 2005

References

Ahn, DU, Wolfe, FH & Sim, JS (1993) Three methods for determining nonheme iron in turkey meat. J Food Sci 58, 288–291.CrossRefGoogle Scholar
Andersen, NL, Fagt, S, Groth, MV, Hartkopp, HB, Møller, A, Ovesen, L & Warming, DL (1996) Danskernes kostvaner 1995, Hovedresultater (Dietary habits of the Danish population, Main results). Publication no. 235. Denmark: Levnedsmiddelstyrelsen (National Food Agency of Denmark).Google Scholar
Bæch, SB, Hansen, M & Bukhave, K (2003) Nonheme-iron absorption from a phytate-rich meal is increased by the addition of small amounts of pork meat. Am J Clin Nutr 77, 173–179.CrossRefGoogle ScholarPubMed
Becker, A (2004) Nordic Nutrition Recommendations. www.norden.org.Google Scholar
Björn-Rasmussen, E & Hallberg, L (1979) Effects of animal proteins in the absorption of food iron in man. Nutr Metab 23, 192–202.CrossRefGoogle ScholarPubMed
Brune, M, Rossander-Hultén, L, Hallberg, L, Gleerup, A & Sandberg, A (1992) Iron absorption from bread in humans: inhibiting effects of cereal fiber, phytate and inositol phosphates with different numbers of phosphate groups. J Nutr 122, 442–449.CrossRefGoogle ScholarPubMed
Carlsson, NG, Bergman, EL, Skoglund, E, Hasselblad, K & Sandberg, AS (2001) Rapid analysis of inositol phosphates. J Agric Food Chem 49, 1695–1701.CrossRefGoogle ScholarPubMed
Cook, JD, Dassenko, SA & Lynch, SR (1991) Assessment of the role of nonheme-iron availability in iron balance. Am J Clin Nutr 54, 717–722.Google ScholarPubMed
Fandrejewski, H, Weremko, W, Migdal, S, Raj, S & Skiba, G (2004) Mechanisms of compensatory growth in pigs. Fatty acids compositions and mineral retention. EU Workshop, Sustainable Pork Production: Welfare, Quality, Nutrition and Consumer Attitudes, Copenhagen, pp. 80–91.Google Scholar
Hallberg, L, Brune, M & Rossander, L (1986) Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum Nutr Appl Nutr 40, 97–113.Google ScholarPubMed
Hallberg, L, Brune, M & Rossander, L (1989) Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate. Am J Clin Nutr 49, 140–144.CrossRefGoogle ScholarPubMed
Hallberg, L & Hulthen, L (2000) Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron. Am J Clin Nutr 71, 1147–1160.CrossRefGoogle ScholarPubMed
Hallberg, L & Rossander, HL (1982a) Effect of different drinks on the absorption of non-haem iron from composite meals. Hum Nutr Appl Nutr 36A, 116–123.Google Scholar
Hallberg, L & Rossander, L (1982b) Absorption of iron from Western-type lunch and dinner meals. Am J Clin Nutr 35, 502–509.CrossRefGoogle ScholarPubMed
Hallberg, L & Rossander, L (1982c) Bioavailability of iron from Western-type whole meals. Scand J Gastroenterol 17, 151–160.CrossRefGoogle ScholarPubMed
Hallberg, L, Rossander, L & Skanberg, AB (1987) Phytates and the inhibitory effect of bran on iron absorption in man. Am J Clin Nutr 45, 988–996.CrossRefGoogle ScholarPubMed
Hallberg, L & Rossander-Hultén, L (1991) Iron requirements in menstruating women. Am J Clin Nutr 54, 1047–1058.CrossRefGoogle ScholarPubMed
Heath, AL & Fairweather-Tait, SJ (2002) Clinical implications of changes in the modern diet: iron intake, absorption and status. Best Pract Res Clin Haematol 15, 225–241.Google ScholarPubMed
Hulten, L, Gramatkovski, E, Gleerup, A & Hallberg, L (1995) Iron absorption from the whole diet. Relation to meal composition, iron requirements and iron stores. Eur J Clin Nutr 49, 794–808.Google ScholarPubMed
Hunt, JR (2003) High-, but not low-bioavailability diets enable substantial control of women's iron absorption in relation to body iron stores, with minimal adaptation within several weeks. Am J Clin Nutr 78, 1168–1177.CrossRefGoogle Scholar
Hunt, JR & Roughead, ZK (2000) Adaptation of iron absorption in men consuming diets with high or low iron bioavailability. Am J Clin Nutr 71, 94–102.CrossRefGoogle ScholarPubMed
Knudsen, E, Sandström, B & Solgaard, P (1996) Zinc, copper and magnesium absorption from a fibre-rich diet. J Trace Elements Med Biol 10, 68–76.Google ScholarPubMed
Layrisse, M, Cook, JD, Martinez, C, et al. (1969) Food iron absorption: a comparison of vegetable and animal foods. Blood 33, 430–443.CrossRefGoogle ScholarPubMed
Martinez-Torres, C & Layrisse, M (1971) Iron absorption from veal muscle. Am J Clin Nutr 24, 531–540.CrossRefGoogle ScholarPubMed
Monsen, ER, Hallberg, L, Layrisse, M, et al. (1978) Estimation of available dietary iron. Am J Clin Nutr 31, 134–141.CrossRefGoogle ScholarPubMed
Morck, TA, Lynch, SR & Cook, JD (1983) Inhibition of food iron absorption by coffee. Am J Clin Nutr 37, 416–420.CrossRefGoogle ScholarPubMed
Reddy, MB, Hurrell, RF & Cook, JD (2000) Estimation of nonheme-iron bioavailability from meal composition. Am J Clin Nutr 71, 937–943.CrossRefGoogle ScholarPubMed
Rossander, L, Hallberg, L & Bjorn-Rasmussen, E (1979) Absorption of iron from breakfast meals. Am J Clin Nutr 32, 2484–2489.CrossRefGoogle ScholarPubMed
Samman, S, Sandstrom, B, Toft, MB, et al. (2001) Green tea or rosemary extract added to foods reduces nonheme-iron absorption. Am J Clin Nutr 73, 607–612.CrossRefGoogle ScholarPubMed
Wienk, KJ, Marx, JJ & Beynen, AC (1999) The concept of iron bioavailability and its assessment. Eur J Nutr 38, 51–75.CrossRefGoogle ScholarPubMed