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Observations on obese patients eating isocaloric reducing diets with varying proportions of carbohydrate

Published online by Cambridge University Press:  09 March 2007

Cathryn E. A. Hood
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
J. M. Goodhart
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
R. F. Fletcher
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
Josephine Gloster
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
P. V. Bertrand
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
A. C. Crooke
Affiliation:
Metabolic Research Unit, East Birmingham Hospital, and the Departments of Medicine and Clinical Endocrinology, University of Birmingham
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Abstract

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1. Diets containing 1000 kcal/day with varying proportions of carbohydrate (CHO) were fed to four women with simple obesity. The patients were given, in various sequences and for 8 days in each instance, diets in which 3, 6, 12, 25 or 50% of the calories were supplied by sucrose.

2. No significant difference in the rate of weight loss was found when the diets of graded CHO content were fed and mean weight loss was 1.2 kg/week.

3. The high-CHO diets were antiketogenic; there was no daily relationship between urinary ketones and sodium. The 25 and 50% CHO diets had a nitrogen-sparing effect.

4. A 1000 kcal/day diet with about a third of the calories derived from CHO leads to a useful rate of weight loss and minimum changes in body chemistry. This finding may have implications in the long-term treatment of obesity.

Type
Research Article
Copyright
Copyright © The Nutrition Society 1970

References

Anderson, A. B. (1944). Q. Jl Med. 37 (OS), 27.Google Scholar
Bloom, W. L. (1962 a). Archs intern. Med. 109, 26.CrossRefGoogle Scholar
Bloom, W. L. (1962 b). J. Lab. clin. Med. 59, 605.Google Scholar
Bloom, W. L. (1967). Am. J. clin. Nutr. 20, 157.CrossRefGoogle Scholar
Bolinger, R. E., Lukert, B. P., Brown, R. W., Guevara, L. & Steinberg, R. (1966). Archs intern. Med. 118, 3.CrossRefGoogle Scholar
Carey, M. E., Pilkington, T. R. E. & Titterington, E. (1962). Lancet ii, 1189.CrossRefGoogle Scholar
Dole, V. P. & Meinertz, H. (1960). J. biol. Chem. 235, 2595.CrossRefGoogle Scholar
Fletcher, R. F., McCririck, M. Y. & Crooke, A. C. (1961). Br. J. Nutr. 15, 53.CrossRefGoogle Scholar
Foster, D. W. (1967). J. clin. Invest. 46, 1283.CrossRefGoogle Scholar
Freund, G. (1965). Metabolism 14, 985.CrossRefGoogle Scholar
Hanson, P. G., Johnson, R. E. & Zaharko, D. S. (1965). Metabolism 14, 1037.CrossRefGoogle Scholar
Jones, J. E., Albrink, M. J., Davidson, P. C. & Flink, E. B. (1966). Am. J. clin. Nutr. 19, 320.CrossRefGoogle Scholar
Kekwick, A. & Pawan, G. L. S. (1956). Lancet ii, 155.CrossRefGoogle Scholar
Kekwick, A., Pawan, G. L. S. & Chalmers, T. M. (1959). Lancet ii, 1157.CrossRefGoogle Scholar
Kempthorne, O. (1952). The Design and Analysis of Experiments. New York: John Wiley.CrossRefGoogle Scholar
Kinsell, L. W., Gunning, B., Michaels, G. D., Richardson, J., Cox, S. E. & Lemon, C. (1964). Metabolism 13, 195.CrossRefGoogle Scholar
Lyon, D. M. & Dunlop, D. M. (1932). Q. Jl Med. 25 (OS), 331.Google Scholar
McCance, R. A. & Widdowson, E. M. (1960). Spec. Rep. Ser. med. Res. Coun. no. 297.Google Scholar
Miller, D. S. & Payne, P. R. (1959). Br. J. Nutr. 13, 501.CrossRefGoogle Scholar
Oleson, E. S. & Quaade, F. (1960). Lancet i, 1048.CrossRefGoogle Scholar
Pilkington, T. R. E., Gainsborough, H., Rosenoer, V. M. & Carey, M. (1960). Lancet i, 856.CrossRefGoogle Scholar
Procos, J. (1961). Clin. Chem. 7, 97.CrossRefGoogle Scholar
Russell, G. F. M. (1962). Clin. Sci. 22, 269.Google Scholar
Subcommittee on Nutrition (1960). J. Am. med. Ass. 173, 1576.CrossRefGoogle Scholar
Werner, S. C. (1955). New Engl. J. Med. 252, 661.CrossRefGoogle Scholar
Yudkin, J. & Carey, M. (1960). Lancet ii, 939.CrossRefGoogle Scholar