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The non-random distribution of copper within the liver of rats

Published online by Cambridge University Press:  09 March 2007

S. Haywood
S. Haywood
Affiliation:
Department of Veterinary Pathology, University of LiverpoolL69 3BX
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Abstract

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1. Two groups of weanling male rats were fed on a powdered proprietary diet for up to 6 weeks. The diet of one group was supplemented with 2 g Cu/kg and the other group received the unsupplemented diet.

2. The livers in the supplemented group accumulated more Cu within the right vascular compartment than the left. This difference was observed in the unsupplemented group after 6 weeks but not at 4 weeks.

3. The distribution of Cu between the different lobes of the livers of the supplemented groups displayed a characteristic pattern, the median lobe containing the most Cu and the omental lobe the least.

4. The distribution of Cu within the liver is thought to reflect the site of its absorption from the gastointestinal tract and a consequence of portal streaming.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 45 , Issue 2 , March 1981 , pp. 295 - 300
Copyright
Copyright © The Nutrition Society 1981

References

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