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Nitrogen retention in rats fed on diets enriched with arginine and glycine

2. Effect of diethyl ether anaesthesia on N retention

Published online by Cambridge University Press:  06 August 2007

H. S. Sitren  and
H. Fisher
H. S. Sitren
Affiliation:
Department of Nutrition, Rutgers University, New Brunswick, New Jersey 08903, USA
H. Fisher
Affiliation:
Department of Nutrition, Rutgers University, New Brunswick, New Jersey 08903, USA
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Abstract

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1. Adult rats were subjected to a brief period of diethyl ether anaesthesia and were given diets with 200 or 100 g casein/kg with or without arginine plus glycine supplementation in the post-anaesthesia period. Nitrogen retention was measured as well as liver protein content and liver and muscle transaminase activities (l-aspartate aminotransferase (GOT), (EC 2.6.1.1), and l-alanine aminotransferase (GPT) (EC 2.6.1.2)).

2. Results demonstrated that anaesthesia-stressed rats consuming the high-protein diet with supplemental arginine and glycine retained twice as much N as did rats given the diet with 200 g casein/kg alone, for the first 5 d post-anaesthesia.

3. Anaesthesia-stressed animals consuming the diets with 100 g casein/kg with or without arginine plus glycine supplementation did not differ from each other in N retention.

4. Liver protein content increased after anaesthesia in rats given the high-protein diets; liver transaminase activity increased, whereas muscle transaminase activity decreased, in animals consuming the high protein diets.

5. Possible mechanisms to account for these results are discussed.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 37 , Issue 2 , March 1977 , pp. 209 - 214
Copyright
Copyright © The Nutrition Society 1977

References

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