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Multi-frequency bioelectric impedance measurements for predicting body water compartments in patients with non-ascitic liver cirrhosis

Published online by Cambridge University Press:  09 March 2007

A. Borghil ,
G. Bedogni ,
E. Rocchi ,
S. Severi ,
F. Farina  and
N. Battistini
A. Borghil
Affiliation:
Department of Internal Medicine, Medicine Clinic III, University of Modena, Via del Pozzo, 41100, Modena, Italy
G. Bedogni
Affiliation:
Department of Biomedical Sciences, Institute of Human Physiology, University of Modena, Via Campi 287, 41100, Modena, Italy
E. Rocchi
Affiliation:
Department of Internal Medicine, Medicine Clinic III, University of Modena, Via del Pozzo, 41100, Modena, Italy
S. Severi
Affiliation:
Department of Biomedical Sciences, Institute of Human Physiology, University of Modena, Via Campi 287, 41100, Modena, Italy
F. Farina
Affiliation:
Department of Internal Medicine, Medicine Clinic III, University of Modena, Via del Pozzo, 41100, Modena, Italy
N. Battistini
Affiliation:
Department of Biomedical Sciences, Institute of Human Physiology, University of Modena, Via Campi 287, 41100, Modena, Italy
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Abstract

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We assessed total body water (TBW) and extracellular water (ECW) in thirty-four non-ascitic cirrhotics and twenty healthy controls by 2H2O and Br dilution. In the same subjects, bioelectric impedance (BI) was recorded at multiple frequencies. Body hydration was similar for controls (mean 55·6 (SD 6·7)), less-severe cirrhotics (Child-Pugh classification A; CPA; n 21, mean 56·2 (SD 6·2)) and moderately-severe cirrhotics (Child-Pugh classification B; CPB; n 13, mean 57·2 (SD 5·4)). However, intracellular water standardized per litre TBW was significantly higher in CPB subjects (mean 27·0 (SD 7·5); P<0·01) compared with CPA (mean 21·3 (SD 10·6)) and control subjects (mean 18·0 (SD 9·8)). Published formulas for predicting TBW and ECW from BI at multiple frequencies were applied to the cirrhotics. These formulas gave accurate predictions of TBW and ECW, although standard errors of estimates were higher for CPB subjects (TBW ≤ 2·5 and ECW ≤ 2·11) than those for CPA (TBW ≤ 2·0 and ECW ≤ 1·81) and control (TBW 1·4 and ECW 0·9 1) subjects

Keywords

Liver cirrhosisTotal body waterExtracellular waterBioelectric impedance
Type
Human and Clinical Nutrition
Information
British Journal of Nutrition , Volume 76 , Issue 3 , September 1996 , pp. 325 - 332
Copyright
Copyright © The Nutrition Society 1996

References

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