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Liver stores of vitamin A in human fetuses in relation to gestational age, fetal size and maternal nutritional status

Published online by Cambridge University Press:  09 March 2007

Raksha S. Shah ,
R. Rajalakshmi ,
R. V. Bhatt ,
M. N. Hazra ,
B. C. Patel ,
N. B. Swamy  and
T. V. Patel
Raksha S. Shah
Affiliation:
Department of Biochemistry, Faculty of Science, M.S. University, Baroda-390002, India
R. Rajalakshmi
Affiliation:
Department of Biochemistry, Faculty of Science, M.S. University, Baroda-390002, India
R. V. Bhatt
Affiliation:
Obstetrics and Gynecology Department, S.S.G. Hospital, Baroda, India
M. N. Hazra
Affiliation:
Obstetrics and Gynecology Department, S.S.G. Hospital, Baroda, India
B. C. Patel
Affiliation:
Obstetrics and Gynecology Department, S.S.G. Hospital, Baroda, India
N. B. Swamy
Affiliation:
Obstetrics and Gynecology Department, S.S.G. Hospital, Baroda, India
T. V. Patel
Affiliation:
Kalpana Clinic, Baroda, India
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Abstract

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1. Studies were made on liver stores of retinol in aborted human fetuses and stillborn babies in relation to gestational age, fetal size and maternal retinol status. The mothers belonged to low-and high-income groups (LIG and HIG respectively) in urban Baroda.

2. Fetal weights were less than those reported by Widdowson (1968) for similar gestational ages and the deficits were greater in LIG.

3. The combined mean values (μg/l) for maternal serum retinol for all gestational ages were 193 for LIG and 261 for HIG. They were found to decline in late pregnancy in the former but not significantly in the latter.

4. Fetal liver retinol concentrations were much lower than those reported for healthy Thai subjects by Montreewasuwat & Olson (1979) in early pregnancy but showed complete ‘catch up’ in late pregnancy for HIG and to a considerable extent for LIG.

5. Significant correlations were found between maternal serum retinol, fetal liver retinol and fetal growth.

6. These findings stress the importance of adequate vitamin A supplies during pregnancy to prevent vitamin A deficiency and intra-uterine growth retardation in the newborn.

Type
Clinical and Human Nutrition papers: Studies in Man
Information
British Journal of Nutrition , Volume 58 , Issue 2 , September 1987 , pp. 181 - 189
Copyright
Copyright © The Nutrition Society 1987

References

REFERENCES

Abramovich, D. R. (1969). Journal of Obstetrics and Gynecology of the British Commonwealth 76, 523–526.CrossRefGoogle Scholar
Achar, S. T. & Yankauer, A. (1962). Indian Journal of Child Health 11, 157–167.Google Scholar
Bhatt, R. V. (1982). Baroda Journal of Nutrition 9, 52–54.Google Scholar
Darby, W. J., McGanity, W. J., Martin, M. P., Bridgforth, E., Densen, P. M., Kaser, M. M., Ogle, P. J., Newbill, J. A., Stockwell, A., Ferguson, M. E., Touster, O., McClellan, G. S., Williams, C. & Cannon, R. O. (1953). Journal of Nutrition 51, 565–597.CrossRefGoogle Scholar
Dave, I. (1980). Nutritional status during pregnancy and lactation. PhD Thesis, M.S.University, Baroda, India.Google Scholar
Ferguson, G. A. (1976). Statistical Analysis in Psychology and Education, 4th ed. Tokyo: McGraw-Hill, Kogakusha Ltd.Google Scholar
Gal, I. & Parkinson, C. E. (1974). American Journal of Clinical Nutrition 27, 688–695.CrossRefGoogle Scholar
Gebre-Medhin, M. & Vahlquist, A. (1984). Acta Paediatrica Scandinavica 73, 333–340.CrossRefGoogle Scholar
Iyengar, L. R. & Apte, S. V. (1972). British Journal of Nutrition 27, 313–317.CrossRefGoogle Scholar
Lakshminarayana, P., Nagaswamy, S. & Balagopala, R. V. (1974). Indian Pediatrics 3, 803–810.Google Scholar
McGanity, W. J., Little, H. M., Fogelman, A., Jennings, L., Calhoun, E. & Dawson, E. B. (1963). American Journal of Obstetrics and Gynecology 103, 773–778.CrossRefGoogle Scholar
Mclaren, D. S., Shirajian, E., Tchalian, M. & Khoury, G. (1965). American Journal of Clinical Nutrition 17, 117–130.CrossRefGoogle Scholar
Montreewasuwat, N. & Olson, J. A. (1979). American Journal of Clinical Nutrition 32, 601–606.CrossRefGoogle Scholar
Moore, T. (1957). Vitamin A. Amsterdam: Elsevier.Google Scholar
National Research Council/National Academy of Science (1978). Laboratory Indices of Nutritional Status in Pregnancy. Washington, DC: National Research Council/National Academy of Science.Google Scholar
Neeld, J. B. & Pearson, W. N. (1963). Journal of Nutrition 79, 454–462.CrossRefGoogle Scholar
Pereira, S. M. & Begum, A. (1973). World Review of Nutrition and Dietetics 19, 2–50.Google Scholar
Rajalakshmi, R. (1971). Tropical Geographic Medicine 23, 117–125.Google Scholar
Rajalakshmi, R. (1980). In Maternal Nutrition During Pregnancy and Lactation, Nestlé Foundation Publication Series, pp. 184–203 [Aebi, H. and Whitehead, R., editors]. Bern: Hans Huber Publishing Co.Google Scholar
Rajalakshmi, R. & Ramakrishnan, C. V. (1969). Gestation and Lactation Performance in Relation to Nutritional Status. Terminal Report of PL 480 Research Project FG-In-224. Baroda, India: Biochemistry Department, M.S. University.Google Scholar
Ramakrishnan, C. V. (1982). Studies on Marasmus and Kwashiorkor Children in Madurai and Trivandrum. Terminal Report. Baroda, India: Biochemistry Department, M.S. University.Google Scholar
Shah, R. S. & Rajalakshmi, R. (1984). American Journal of Clinical Nutrition 40, 794–800.CrossRefGoogle Scholar
Skurnik, L., Heikel, H. & Westerberg, T. U. (1944). Zeitschrift für Vitaminforschung 15, 68–76.Google Scholar
Tarwotjo, I., Sommer, A., Soegiharto, T., Susanto, D. & Muhilal, H. (1982). American Journal of Clinical Nutrition 35, 574–581.CrossRefGoogle Scholar
Thomson, A. M. & Hytten, F. E. (1966). In Nutrition, vol. 3, pp. 104–143. [Beaton, G. H. and McHenry, E. W., editors]. New York: Academic Press.Google Scholar
Udani, P. M. (1963). Indian Journal of Child Health 12, 593–611.Google Scholar
Venkatachalam, P. S., Belavady, B. & Gopalan, C. (1962). Journal of Pediatrics 61, 262–268.CrossRefGoogle Scholar
Venkatachalam, P. S. & Gopalan, C. (1960). Indian Journal of Medical Research 48, 645–653.Google Scholar
Widdowson, E. M. (1968). In Biology of Gestation vol. 2, The Fetus and the Neonate, pp. 1–49 [ Assali, N.S., editor]. New York: Academic Press.Google Scholar
Woo, T. T. & Chu, F. T. (1939). Chinese Journal of Physiology 15, 83–99.Google Scholar