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Lime-treated maize husks lower plasma LDL-cholesterol levels in normal and hypercholesterolaemic adult men from northern Mexico

Published online by Cambridge University Press:  09 March 2007

Reyna Luz Vidal-Quintanar ,
Reyna Luz Mendívil ,
Mireya Peña  and
Maria Luz Fernandez
Reyna Luz Vidal-Quintanar
Affiliation:
Departamento de Investigación y Posgrado en Alimentos University of Sonora, Hermosillo, Sonora, Mexico
Reyna Luz Mendívil
Affiliation:
Departamento de Investigación y Posgrado en Alimentos University of Sonora, Hermosillo, Sonora, Mexico
Mireya Peña
Affiliation:
Departamento de Investigación y Posgrado en Alimentos University of Sonora, Hermosillo, Sonora, Mexico
Maria Luz Fernandez*
Affiliation:
Departamento de Investigación y Posgrado en Alimentos University of Sonora, Hermosillo, Sonora, Mexico
*
*Corresponding author: Dr Maria Luz Fernandez, fax +1 860 486 3674, email [email protected]
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Abstract

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Lime-treated maize husks (LTCH), a by-product of tortilla manufacturing in Mexico, have been shown to decrease plasma LDL-cholesterol levels in guinea-pigs by specific alterations in hepatic cholesterol metabolism. To determine whether LTCH would also lower plasma cholesterol levels in normal and hyperlipidaemic individuals, the fibre content of a typical diet was increased by supplementing free-living subjects in North-West Mexico with cookies containing 450 g LTCH/kg. Normal subjects (n 11) with plasma cholesterol levels of less than 5·7 mmol/l and hypercholesterolaemic subjects (n 12) with plasma cholesterol levels higher than 5·7 mmol/l participated in the study. Plasma glucose, cholesterol, triacylglycerol, LDL-cholesterol and HDL-cholesterol concentrations, LDL: HDL values and blood pressure were determined at baseline and after 6 weeks of supplementation with LTCH. LTCH supplementation significantly lowered the plasma total cholesterol level by 11–15 % and LDL-cholesterol by 25 %, and improved the LDL: HDL value by 29–33 % (P < 0·01) in both normal and hypercholesterolaemic subjects. HDL-cholesterol, triacylglycerol and glucose concentrations did not change. Both groups consumed equal amounts of LTCH per week; individuals showed excellent compliance and good acceptance of the product. Neither group changed their dietary habits during the time of the experiment as determined by 3 d dietary records at baseline and at week 6. We conclude that LTCH supplements are suitable to increase fibre intake and reduce plasma LDL-cholesterol levels in healthy and hypercholesterolaemic subjects in this population.

Keywords

Maize husksPlasma cholesterolDietary fibre
Type
Research Article
Information
British Journal of Nutrition , Volume 81 , Issue 4 , April 1999 , pp. 281 - 288
Copyright
Copyright © The Nutrition Society 1999

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