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Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol

Published online by Cambridge University Press:  08 March 2007

Ivon E. J. Milder ,
Ilja C. W. Arts ,
Betty van de Putte ,
Dini P. Venema  and
Peter C. H. Hollman
Ivon E. J. Milder
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, PO Box 230, 6700 AE Wageningen, The Netherlands Centre for Nutrition and Health, National Institute for Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, The Netherlands
Ilja C. W. Arts
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, PO Box 230, 6700 AE Wageningen, The Netherlands
Betty van de Putte
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, PO Box 230, 6700 AE Wageningen, The Netherlands
Dini P. Venema
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, PO Box 230, 6700 AE Wageningen, The Netherlands
Peter C. H. Hollman*
Affiliation:
RIKILT-Institute of Food Safety, Wageningen University and Research Centre, PO Box 230, 6700 AE Wageningen, The Netherlands
*
*Corresponding author: Dr Peter C. H. Hollman, fax +31 317 417717, email [email protected]
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Abstract

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Enterolignans (enterodiol and enterolactone) can potentially reduce the risk of certain cancers and cardiovascular diseases. Enterolignans are formed by the intestinal microflora after the consumption of plant lignans. Until recently, only secoisolariciresinol and matairesinol were considered enterolignan precursors, but now several new precursors have been identified, of which lariciresinol and pinoresinol have a high degree of conversion. Quantitative data on the contents in foods of these new enterolignan precursors are not available. Thus, the aim of this study was to compile a lignan database including all four major enterolignan precursors. Liquid chromatography–tandem mass spectrometry was used to quantify lariciresinol, pinoresinol, secoisolariciresinol and matairesinol in eighty-three solid foods and twenty-six beverages commonly consumed in The Netherlands. The richest source of lignans was flaxseed (301 129 μg/100 g), which contained mainly secoisolariciresinol. Also, lignan concentrations in sesame seeds (29 331 μg/100 g, mainly pinoresinol and lariciresinol) were relatively high. For grain products, which are known to be important sources of lignan, lignan concentrations ranged from 7 to 764 μg/100 g. However, many vegetables and fruits had similar concentrations, because of the contribution of lariciresinol and pinoresinol. Brassica vegetables contained unexpectedly high levels of lignans (185–2321 μg/100 g), mainly pinoresinol and lariciresinol. Lignan levels in beverages varied from 0 (cola) to 91 μg/100 ml (red wine). Only four of the 109 foods did not contain a measurable amount of lignans, and in most cases the amount of lariciresinol and pinoresinol was larger than that of secoisolariciresinol and matairesinol. Thus, available databases largely underestimate the amount of enterolignan precursors in foods.

Keywords

LignansPhytoestrogensFood compositionSecoisolariciresinolMatairesinolPinoresinolLariciresinol
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 3 , March 2005 , pp. 393 - 402
Copyright
Copyright © The Nutrition Society 2005

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