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Iodine metabolism in children and women with endemic goitre in Ceylon

Published online by Cambridge University Press:  26 July 2012

M. G. Deo  and
T. A. V. Subramanian
M. G. Deo
Affiliation:
Department of Pathology, All-India Institute of Medical Sciences, New Delhi, India
T. A. V. Subramanian
Affiliation:
Department of Biochemistry, Vallabhbhai Pate1 Chest Institute, New Delhi, India
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Abstract

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1. Iodine metabolism was studied using labelled sodium iodide in subjects with endemic goitre which is prevalent in the south-west part of Ceylon, where the iodine content of the drinking water was shown to be low. The study was confined mostly to children of school age.

2. The patients showed raised thyroidal uptake of 181I and 48 h serum protein-bound radio-active iodine, lowered plasma inorganic iodide and urinary iodide.

3. These findings suggest that the goitre which is endemic in Ceylon is due to environmental iodine deficiency rather than to a goitrogen.

Type
Research Article
Information
British Journal of Nutrition , Volume 25 , Issue 1 , January 1971 , pp. 97 - 105
Copyright
Copyright © The Nutrition Society 1971

References

REFERENCES

Adam, D. D., Kennedy, T. H., Choufoer, J. C. & Querido, A. (1968). J. clin. Endocr. Metab. 28, 685.CrossRefGoogle Scholar
Ahuja, M. M. S. & Kochupillai, N. (1967). Proceedings of the Third Asia and Oceania Endocrinology Congress, Manila, Philippines, January, p. 256.Google Scholar
Barker, S. B., Humphrey, M. J. & Soley, M. H. (1951). J. clin. Invest. 30, 55.CrossRefGoogle Scholar
Beckers, C., Barzelatto, J., Stevenson, C., Gianetti, A., Pardo, A., Babadilla, P. & De Visscher, M. (1965). Proceedings of the Fifth International Thyroid Congress, p.838.Google Scholar
Bois, I. & Larsson, L. G. (1958). Acta endow., Copenh. 28, 262.Google Scholar
Choufoer, J. C., van Rhijn, M., Kassenaar, A. A. H. & Querido, A. (1963). J. clin. Endocr. Metab. 23, 1203.CrossRefGoogle Scholar
Clements, F. W. & Wishart, J. W. (1956). Metabolism 6, 623.Google Scholar
De Visscher, M., Beckers, C., van den Schrieck, H. G., De Smet, M., Ermans, A. M., Galperin, H. & Bastenie, P. A. (1961). J. clin. Endocr. Metab. 21, 175.CrossRefGoogle Scholar
Ekpechi, O. L. (1967). Br. J. Nutr. 21, 537.CrossRefGoogle Scholar
Follis, R. H. (1964). Med. Clins N. Am. 48, 1219.CrossRefGoogle Scholar
Follis, R. H. Jr, Vanprapa, K. & Damrongsakdi, D. (1962). J. Nutr. 76, 159.CrossRefGoogle Scholar
Foote, J. B. & Maclagan, N. F. (1951). Lancet i, 868.CrossRefGoogle Scholar
Greenwald, I. (1955). Fedn Proc. Fedn Am. Socs exp. Biol. 14, 435.Google Scholar
Greer, M. A. & Astwood, E. B. (1948). Endocrinology 43, 105.CrossRefGoogle Scholar
Harden, R. M., Mason, D. K. & Watson, W. (1965). J. Lab. clin. Med. 65, 500.Google Scholar
Kelly, F. C. & Snedden, W. W. (1958). Bull. Wld Hlth Org. 18, 5.Google Scholar
King, E. J. & Wootton, I. D. P. (1956). Micro-analysis in Medical Biochemistry 3rd ed.London: Churchill.Google Scholar
London, W. T., Koutras, D. A., Pressman, A. & Vought, R. L. (1965). J. clin. Endocr. Metab. 25, 1091.CrossRefGoogle Scholar
McCarrison, R. (1917). The Thyroid Gland. London: Baillière, Tindall & Cox.Google Scholar
McGirr, E. M. & Greig, W. R. (1968). Proc. R. Soc. Med. 61, 385.Google Scholar
Mahadeva, K. & Shanmuganathan, S. S. (1967). Br. J. Nutr. 21, 341.CrossRefGoogle Scholar
Murray, M. M., Ryle, J. A., Simpson, B. W. & Wilson, D. C. (1948). Med. Res. Coun. Memo. no. 18.Google Scholar
Petola, P. (1965). Proceedings of the Fifth International Thyroid Congress, p.872.Google Scholar
Ramalingaswami, V., Subramanian, T. A. V. & Deo, M. G. (1961). Lancet i, 791.CrossRefGoogle Scholar
Raman, G. & Beierwaltes, W. H. (1959). J. clin. Endocr. Metab. 19, 228.CrossRefGoogle Scholar
Roche, M., De Vananzi, F., Vera, J., Coll, E., Spinetti-Berti, M., Mendez-Martinez, J., Gerardi, A. & Forero, J. (1957). J. clin. Endocr. Metab. 17, 99.CrossRefGoogle Scholar
Roche, M., Perinetti, H. & Barbeito, A. (1961). J. clin. Endocr. Metab. 21, 1009.CrossRefGoogle Scholar
Roy, S., Deo, M. G. & Ramalingaswami, V. (1964). Am. J. Path. 44, 839.Google Scholar
Silver, S., Fieber, M. H. & Yohalem, S. B. (1952). Am. J. Med. 13, 725.CrossRefGoogle Scholar
Srinivasan, S., Subramanian, T. A. V., Sinha, A., Deo, M. G. & Ramalingaswami, V. (1964). Lancet ii, 176.CrossRefGoogle Scholar
Stanbury, J. B. (1958). Fedn Proc. Fedn Am. Socs exp. Biol. 17, Suppl. 2, p. 83.Google Scholar
Stanbury, J. B., Brownwell, G. L., Riggs, D. S., Perinetti, H., Itoiz, J. & del castillo, E. B. (1954). Endemic Goiter: The Adaptation of Man to Iodine Deficiency. Cambridge, Mass.: Harvard University Press.CrossRefGoogle Scholar
Stott, H., Bhatia, B. B., Lal, R. S. & Rai, K. C. (1931). Indian J. med. Res. 18, 1059.Google Scholar
Vought, R. L., London, W. T., Lutwak, L. & Dublin, T. D. (1963). J. clin. Endocr. Metab. 23, 1218.CrossRefGoogle Scholar
Vought, R. L., London, W. T. & Stebbing, G. E. T. (1967). J. clin. Endocr. Metab. 27, 1381.CrossRefGoogle Scholar
Wayne, E. J., Koutras, D. A. & Alexander, W. D. (editors) (1964). Clinical Aspects of Iodine Metabolism. Oxford: Blackwell Scientific Publications.Google Scholar
Wilson, D. C. (1941). Lancet ii, 211.CrossRefGoogle Scholar
Wilson, D. C. (1954). Br. J. Nutr. 8, 90.CrossRefGoogle Scholar