Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-23T02:07:34.706Z Has data issue: false hasContentIssue false
  • English
  • Français

Intrinsic labelling of different foods with stable isotope of zinc (67Zn) for use in bioavailability studies

Published online by Cambridge University Press:  09 March 2007

Thomas E. Fox ,
Susan J. Fairweather-Tait ,
John Eagles  and
S. Gabrielle Wharf
Thomas E. Fox
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
Susan J. Fairweather-Tait
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
John Eagles
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
S. Gabrielle Wharf
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Intrinsically-labelled foods are required to validate extrinsic-labelling techniques used to study the bioavailability of trace elements. Wheat (Triticum aestivum), peas (Pisum sativum), goat's milk, human milk, eggs and chicken meat were selected for intrinsic-labelling studies with 67Zn. Peas were grown hydroponically in enriched nutrient solution and wheat was grown in sand and watered with enriched nutrient solution. Some of the wheat plants were also given stem injections of 67Zn solution. Eggs and chicken meat were prepared by administering 67Zn intravenously to chickens, and human milk was collected after an oral dose of 67Zn in a cola drink. All the foods investigated were sufficiently enriched with 67Zn for Zn absorption studies except wheat prepared by the sand and water-culture method.

Keywords

Intrinsically-labelled foodsBioavailabilityZn
Type
Bioavailability and Utilization of Inorganic Nutrients
Information
British Journal of Nutrition , Volume 66 , Issue 1 , July 1991 , pp. 57 - 63
Copyright
Copyright © The Nutrition Society 1991

References

REFERENCES

Burk, R. F. & Solomons, N. W. (1985). Trace elements and vitamins and bioavailability as related to wheat and wheat foods. American Journal of Clinical Nutrition 41, 1091–1102.CrossRefGoogle ScholarPubMed
Davids, K. R., Peters, L. L., Cain, R. F., LeTourneau, D. & McGinnis, J. (1984). Evaluation of the nutrient composition of wheat Ill: minerals. Cereal Foods World 29, 246–248.Google Scholar
Eagles, J., Fairweather-Tait, S. J., Portwood, D. E., Self, R., Gotz, A. & Heumann, G. (1989). Comparison of fast atom bombardment mass spectrometry and thermal ionization quadrupole mass spectrometry for the measurement of zinc absorption in human nutrition studies. Analytical Chemistry 61, 1023–1025.CrossRefGoogle ScholarPubMed
Evans, G. W. & Johnson, P. E. (1977). Determination of zinc availability in foods by the extrinsic label technique. American Journal of Clinical Nutrition 30, 873–878.CrossRefGoogle ScholarPubMed
Flanagan, P. R., Cluett, J., Chamberlain, M. J. & Valberg, L. S. (1985). Dual-isotope method for determination of human zinc absorption: the use of a test meal of turkey meat. Journal of Nutrition 115, 111–122.CrossRefGoogle ScholarPubMed
Gallaher, D. D., Johnson, P. E., Hunt, J. R., Lykken, G. I. & Marchello, M. (1988). Bioavailability in humans of zinc from beef: intrinsic v. extrinsic labels. American Journal of Clinical Nutrition 48, 350–354.CrossRefGoogle Scholar
Hambidge, K. M. (1989). Mild zinc deficiency in human subjects. In Zinc in Human Biology, pp. 281–296 [Mills, C. F., editor]. London: Springer-Verlag.CrossRefGoogle Scholar
Hamilton, B. C. & O'Brien, T. P. (1979). Aspects of vascular anatomy and differentiation of vascular tissues and transfer cells in vegetative nodes of wheat. Australian Journal of Botany 27, 703–711.Google Scholar
Janghorbani, M., Istfan, N. W., O'Pagounes, J., Steinke, F. H. & Young, V. R. (1982). Absorption of dietary zinc in man: comparison of intrinsic and extrinsic labels using a triple stable isotope method. American Journal of Clinical Nutrition 36, 537–545.CrossRefGoogle ScholarPubMed
Krebs, N. F., Hambidge, K. M., Jacobs, M. A. & Rasbach, J. O. (1985). The effects of dietary zinc supplement during lactation on longitudinal changes in maternal zinc status and milk zinc concentrations. American Journal of Clinical Nutrition 41, 560–570.CrossRefGoogle ScholarPubMed
Layrisse, M., Cook, J. D., Martinez, C., Roche, M., Kuhn, I. N., Walker, R. B. & Finch, C. A. (1969). Food iron absorption: a comparison of vegetable and animal foods. Blood 33, 430–443.CrossRefGoogle ScholarPubMed
Meyer, N. R., Stuart, M. A. & Weaver, C. M. (1983). Bioavailability of zinc from defatted soy flour, soy hulls and whole eggs as determined by intrinsic and extrinsic labelling techniques. Journal of Nutrition 113, 1255–1264.CrossRefGoogle Scholar
Noggle, G. R. & Fritz, G. J. (1976). Introductory Plant Physiology. New York: Prentic Hall Inc.Google Scholar
Paul, A. A. & Southgate, D. A. T. (1978). McCance and Widdowson's The Composition of Foods. London: H.M. Stationery Office.Google Scholar
Serfass, R. E., Lindberg, G. L., Olivares, J. A. & Houk, R. S. (1987). Intrinsic labelling of bovine milk with enriched stable isotopes of zinc. Proceedings of the Society for Experimental Biology and Medicine 186, 113–117.CrossRefGoogle ScholarPubMed
Simpson, R. J., Lambers, H. & Dalling, M. J. (1983). Nitrogen redistribution during grain growth in wheat (Triticum aestivum). Physiology Plant 56, 11–17.CrossRefGoogle Scholar
Starks, T. L. & Johnson, P. E. (1985). Techniques for intrinsically labelling wheat with 65Zn. Journal of Agricultural Food Chemistry 33, 691–698.CrossRefGoogle Scholar
Waldren, R. P. & Flowerday, A. D. (1979). Growth stages and distribution of dry matter, N, P and K in winter wheat. Agronomy Journal 71, 391–397.CrossRefGoogle Scholar
Weaver, C. M. (1985). Intrinsic mineral labelling of edible plants: methods and uses. Critical Reviews in Food Science and Nutrition 23, 75–101.CrossRefGoogle ScholarPubMed
Zee, S. T. & O'Brien, T. P. (1970). A special type of tracheary element associated with xylem discontinuity in the floral axis of wheat. Australian Journal of Biological Science 23, 783–791.CrossRefGoogle Scholar