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Intestinal absorption of calcium in rats given diets containing casein or amino acid mixture: the role of casein phosphopeptides

Published online by Cambridge University Press:  09 March 2007

Yeon Sook Lee ,
Tadashi Noguchi  and
Hiroshi Naito
Yeon Sook Lee*
Affiliation:
Department of Agricultural Chemistry, University of Tokyo, Bunkyo-Ku, Tokyo 113, Japan
Tadashi Noguchi
Affiliation:
Department of Agricultural Chemistry, University of Tokyo, Bunkyo-Ku, Tokyo 113, Japan
Hiroshi Naito*
Affiliation:
Department of Agricultural Chemistry, University of Tokyo, Bunkyo-Ku, Tokyo 113, Japan
*
* Present address: Department of Home Economics, College of Agriculture, Seoul National University, Suweon, Korea.
† For reprints.
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Abstract

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1. In an attempt to investigate calcium absorption in the rat during the postprandial period, with the least alteration of the physical environment, the undisturbed small intestine was ligated in situ 2·5 or 3·0 h after ingestion of a diet containing 200 g casein/kg or an equivalent amino acid mixture, or 925 g casein/kg. Estimation of Ca absorption was made by comparing the amount of soluble 40Ca or 45Ca in the contents of segments from the rats receiving 45Ca by intubation 30 min after withdrawal of food, ligated after a further 30 min, then killed after 0 or 30 min.

2. Under conditions such that the estimated amount of a marker, polyethylene glycol, in segments ligated in a defined position was little changed in rats killed 30 min apart, the difference in the amount of soluble 40Ca was much higher in the rats fed on the basal diet containing 200 g casein/kg than in other groups.

3. This specific effect on Ca absorption, particularly in the distal portion of the small intestine, could be seen also after 45Ca was directly injected into ligated segments in situ. The amount of 45Ca in the portal blood 15 min after injection of the label was also highest in the rats given the basal diet.

4. The results were in agreement with our previous findings that the formation and accumulation of casein phosphopeptides causes an increase in the amount of soluble Ca in the distal small intestine.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 49 , Issue 1 , January 1983 , pp. 67 - 76
Copyright
Copyright © The Nutrition Society 1983

References

Ahrens, R. A., Wilson, J. E. Jr. & Womack, M. (1966). J. Nutr. 88, 219.CrossRefGoogle Scholar
Forbes, R. M., Weingartner, K. E., Parker, H. M., Bell, R. R. & Erdman, J. W. Jr. (1979). J. Nutr. 109, 1652.CrossRefGoogle Scholar
Kawakami, M. & Shimura, K. (1974). Radioisotopes 23, 15.Google Scholar
Lee, Y. S., Noguchi, T. & Naito, H. (1979). Agric. Biol. Chem. 43, 457.Google Scholar
Lee, Y. S., Noguchi, T. & Naito, H. (1980). Br. J. Nutr. 43, 457.CrossRefGoogle Scholar
Marcus, C. S. & Lengemann, F. W. (1962). J. Nutr. 77, 155.Google Scholar
Mellander, O. (1950). Uppsala Läkarefören Förhandl. 52, 107.Google Scholar
Mellander, O. (1963). In The Transfer of Calcium and Strontium Across Biological Membranes, p. 265 [Wasserman, R. H., editor]. New York: Academic Press.Google Scholar
Mykänen, H. M. & Wasserman, R. H. (1980). J. Nutr. 110, 2141.CrossRefGoogle Scholar
Naito, H., Kawakami, A. & Imamura, T. (1972). Agric. Biol. Chem. 36, 409.Google Scholar
Naito, H., Suzuki, H. (1974). Agric. Biol. Chem. 38, 543.CrossRefGoogle Scholar
National Academy of Sciences (1972). Nutrient Requirements of Domestic Animals, 2nd ed., p. 64. Washington, DC: (US) National Academy of Sciences.Google Scholar
Rogers, Q. R. & Harper, A. E. (1965). J. Nutr. 87, 267.CrossRefGoogle Scholar
Wasserman, R. H. (1961). Science 133, 883.CrossRefGoogle Scholar
Wasserman, R. H. & Taylor, A. N. (1976). Handbook of Physiology vol. 7, p. 137 [Greep, R. O. and Astwood, E. B., editors]. Washington, DC: American Physiological Society.Google Scholar