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Influence of the level of dietary phosphorus on the voluntary intake of energy and metabolic utilization of nutrients in the growing rat

Published online by Cambridge University Press:  09 March 2007

Y. Henry ,
L. Gueguen  and
A. Rérat
Y. Henry
Affiliation:
Station de Recherches sur I'Elevage des Pores, Station de Recherches de Nutrition and Labora-toire de Physiologie de la Nutrition, INRA 78350 Jouy-en-Josas, France
L. Gueguen
Affiliation:
Station de Recherches sur I'Elevage des Pores, Station de Recherches de Nutrition and Labora-toire de Physiologie de la Nutrition, INRA 78350 Jouy-en-Josas, France
A. Rérat
Affiliation:
Station de Recherches sur I'Elevage des Pores, Station de Recherches de Nutrition and Labora-toire de Physiologie de la Nutrition, INRA 78350 Jouy-en-Josas, France
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Abstract

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1. An experiment was carried out on growing male rats to study the effects of a phosphorus deficiency on voluntary energy intake, estimated by the separate-feeding technique, as well as the consequences on growth and metabolic utilization of energy, protein and minerals. After a preliminary period of P deprivation, three groups of twelve animals were fed separately and simultaneously two dietary rations. A protein ration provided 1.2 g protein/d to which was added one of three levels of P in the form of monosodium phosphate: a normal level of 35.4 mg/d (treatment A), half the normal level (19.1 mg/d, treatment B) or one-quarter the normal level (9.6 mg/d, treatment C). Another protein-free ration was fed ad lib.

2. It was only when the level of P represented one quarter the normal level that a significant decrease in growth rate was noticed, accompanied by a definite decrease in daily energy consumption. The food conversion ratio (g dry matter intake/g body-weight gain) increased whereas the protein efficiency ratio (g body-weight gain/g protein intake) was lower. The nitrogen and energy retentions changed in the same way: both dectreased with treatment C compared to treatment A and B. Independently of the protein supply, the voluntary energy intake was closely related to the intensity of protein retention, which depended on the dietary level of P. The daily retention of P only slightly decreased at the lowest ingestion level (9.6 mg/d in treatment C), compared to that of the higher levels. On the other hand, the amount of calcium retained regularly decreased with the decreasing supply of P. The result of this was a progressive reduction in retained Ca:P as the level of P decreased.

3. From these results it appeared that the primary effect of a P deficiency in the growing rat was a decrease in bone mineralization. At a more advanced stage, the tissue P levels were affected and the resulting metabolic alterations reduced protein deposition and consequently the voluntary energy intake. The level of energy consumption, in separate-feeding, is more generally dependent on the level of protein deposition allowed by the limiting factor for growth, either protein, minerals or vitamins.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 42 , Issue 1 , July 1979 , pp. 127 - 137
Copyright
Copyright © The Nutrition Society 1979

References

Ashley, D. V. M. & Anderson, G. H. (1975). J. Nutr. 105, 1405.CrossRefGoogle Scholar
Atwater, W. O. & Bryant, A. P. (1903). U.S. Dept. Agr. Bull. 28.Google Scholar
Baylink, D., Wergedal, J. & Stauffer, M. (1971). J. clin. Invest. 50, 2519.CrossRefGoogle Scholar
Blaizot, S. & Blaizot, J. (1969). Annals Nutr. Aliment. 23, 117.Google Scholar
Day, H. G. & McCollum, E. V. (1939). J. biol. Chem. 130, 269.CrossRefGoogle Scholar
Hegsted, D. M. (1974). Nutr. Rev. 32, 33.CrossRefGoogle Scholar
Henry, Y. (1968). Annls Nutr. Aliment. 23, 121.Google Scholar
Henry, Y. & Rérat, A. (1962). Annls Biol. anim. Biochim. Biophys. 2, 267.Google Scholar
Henry, Y. & Rérat, A. (1963). Annls Biol. anim. Biochim. Biophys. 3, 103.CrossRefGoogle Scholar
Henry, Y. & Rérat, A. (1964). C.r. Lebd. Séanc. Acad. Sci., Paris 258, 3915.Google Scholar
Henry, Y. & Rérat, A. (1966). Amino acides, Peptides et Protéines. Cahiers Alimentation équilibrée de Commentry, Vol. 6, p. 240. Commentry, France.Google Scholar
Henry, Y. & Rérat, A. (1969). Annls Biol. anim. Biochim. Biophys. 9, 601.Google Scholar
Jacquot, R. & Péret, J. (1972). In Protein and Amino Acid Functions, p. 317 [Bigwood, E. T., editor]. Oxford: Pergamon Press.Google Scholar
Mayer, J. (1964). In Nutrition: A Comprehensive Treatise, Vol. 1, p. 1 [Beaton, G. H. and McHenry, E. W., editors]. New York: Academic Press.Google Scholar
Mickelsen, O. & Anderson, A. A. (1959). J. Lab. clin. Med. 53, 282.Google Scholar
Mitchell, H. H. (1959). In Protein and Amino Acid Nutrition, p. 11 [Albanese, A. A., editor]. New York: Academic Press.Google Scholar
Musten, B., Peace, D. & Anderson, G. H. (1974). J. Nutr. 104, 563.CrossRefGoogle Scholar
National Research Council. (1972). Nutrient Requirements of Laboratory Animals. Washington, D.C.: National Academy of Science.Google Scholar
Pearson, E. S. & Hartley, H. O. (1956). Biometrika Tables for Statisticians, Vol. 1, p. 176. Cambridge: Cambridge University Press.Google Scholar
Pol, G. & Den Hartog, C. (1966). Br. J. Nutr. 20, 649.CrossRefGoogle Scholar
Rérat, A. & Henry, Y. (1963). Annals Biol. anim. Biochim. Biophys. 3, 263.CrossRefGoogle Scholar
Rérat, A., Henry, Y. & Jacquot, R. (1963). C.r. Lebd. Séanc. Acad. Sci. 256, 787.Google Scholar
Rosen, M. & Levinger, I. M. (1972). Lab. Animals 6, 287.CrossRefGoogle Scholar
Rozin, P. (1968). J. comp. physiol. Psychol. 65, 23.Google Scholar
Snedecor, G. W. & Cochran, W. G. (1967). Statistical Methods Applied to Experiments in Agriculture and Biology, 6th ed. Ames. Iowa: Iowa State University Press.Google Scholar
Spray, E. M. & Widdowson, E. M. (1950). Br. J. Nutr. 4, 332.CrossRefGoogle Scholar
Szepesi, B. & Oney, M. L. (1977). Nutr. Rep. Int. 16, 59.Google Scholar
Widdowson, E. M. & Dickerson, J. W. T. (1964). In Mineral Metabolism, Vol. 2A [Comar, C. L. & Bronner, F., editors]. New York: Academic Press.Google Scholar