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Influence of amount of dietary fat and protein on esterase-1 (ES-1) activities of plasma and small intestine in rats

Published online by Cambridge University Press:  09 March 2007

H. A. Van Lith ,
G. W. Meijer ,
M. J. A. van der Wouw ,
M. Den Bieman ,
G. Van Tintelen ,
L. F. M. Van Zutphen  and
A. C. Beynen
H. A. Van Lith
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
G. W. Meijer
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
M. J. A. van der Wouw
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
M. Den Bieman
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
G. Van Tintelen
Affiliation:
Laboratory Animals Centre Agricultural University, PO Box 8129, 6700 EV Wageningen, The Netherlands
L. F. M. Van Zutphen
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
A. C. Beynen
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht Department of Human Nutrition, Agricultural University, PO Box 8129, 6700 EV Wageningen, The Netherlands
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Abstract

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The objective of the present study was to characterize nutritionally esterase-1 (ES-1). For this purpose, the effects of replacement of dietary carbohydrates by isoenergetic amounts of either fat or protein on ES-1 activities of plasma and small intestine were studied in male rats. Purified diets differing in the amounts of maize starch plus dextrose, casein and various types of fat were used. Plasma and jejunal ES-1 activities were found to be increased with increasing fat intakes. As to the type of fat, increasing plasma ES-1 activities were induced by coconut fat, olive oil, maize oil and medium-chain triacylglycerols, in this order. Maize oil induced higher jejunal ES-1 activities than coconut fat and olive oil, but had similar effects to medium-chain triacylglycerols. Maize oil was more powerful in increasing plasma ES-1 activity than isoenergetic amounts of casein, but with respect to jejunal ES-1 activity these dietary components were equally effective. It is concluded that the amounts of fat and protein in the diet are important determinants of ES-1 activities in plasma and jejunum.

Keywords

Dietary fatEsterase-1PlasmaIntestineRat
Type
Metabolic Effects of Diet
Information
British Journal of Nutrition , Volume 67 , Issue 3 , May 1992 , pp. 379 - 390
Copyright
Copyright © The Nutrition Society 1992

References

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