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Infant intake of fatty acids from human milk over the first year of lactation

Published online by Cambridge University Press:  09 March 2007

Leon R. Mitoulas ,
Lyle C. Gurrin ,
Dorota A. Doherty ,
Jillian L. Sherriff  and
Peter E. Hartmann
Leon R. Mitoulas*
Affiliation:
Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, Faculty of Life and Physical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
Lyle C. Gurrin
Affiliation:
Women and Infants Research Foundation and The University of Western AustraliaDepartment of Obstetrics and Gynaecology, King Edward Memorial Hospital, Subiaco WA 6008, Australia
Dorota A. Doherty
Affiliation:
Women and Infants Research Foundation and The University of Western AustraliaDepartment of Obstetrics and Gynaecology, King Edward Memorial Hospital, Subiaco WA 6008, Australia
Jillian L. Sherriff
Affiliation:
Department of Nutrition, Dietetics and Food Science, School of Public Health, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia
Peter E. Hartmann
Affiliation:
Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, Faculty of Life and Physical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
*
*Corresponding author: Dr L. R. Mitoulas, fax +61 8 9380 1148, email [email protected]
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Abstract

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Despite the importance of human milk fatty acids for infant growth and development, there are few reports describing infant intakes of individual fatty acids. We have measured volume, fat content and fatty acid composition of milk from each breast at each feed over a 24h period to determine the mean daily amounts of each fatty acid delivered to the infant from breast milk at 1, 2, 4, 6, 9 and 12 months of lactation in five women. Daily (24h) milk production was 336·60 (sem 26·21) and 414·49 (sem 28·39) ml and milk fat content was 36·06 (sem 1·37) and 34·97 (sem 1·50) g/l for left and right breasts respectively over the course of the first year of lactation. Fatty acid composition varied over the course of the day (mean CV 14·3 (sd 7·7) %), but did not follow a circadian rhythm. The proportions (g/100g total fatty acids) of fatty acids differed significantly between mothers (P<0·05) and over the first year of lactation (P<0·05). However, amounts (g) of most fatty acids delivered to the infant over 24h did not differ during the first year of lactation and only the amounts of 18:3n-3, 22:5n-3 and 22:6n-3 delivered differed between mothers (P<0·05). Mean amounts of 18:2n-6, 18:3n-3, 20:4n-6 and 22:6n-3 delivered to the infant per 24h over the first year of lactation were 2·380 (sd 0·980), 0·194 (sd 0·074), 0·093 (sd 0·031) and 0·049 (sd 0·021) g respectively. These results suggest that variation in proportions of fatty acids may not translate to variation in the amount delivered and that milk production and fat content need to be considered.

Keywords

Fatty acidsInfant nutritionHuman milk lipidsSampling protocolsBreast-feeding
Type
Research Article
Information
British Journal of Nutrition , Volume 90 , Issue 5 , November 2003 , pp. 979 - 986
Copyright
Copyright © The Nutrition Society 2003

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