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Hyperinsulinaemia, supplemental protein and branched-chain amino acids when combined can increase milk protein yield in lactating sows

Published online by Cambridge University Press:  08 March 2007

Frank R. Dunshea ,
Dale E. Bauman ,
Elizabeth A. Nugent ,
Douglas J. Kerton ,
Raymond H. King  and
Ian McCauley
Frank R. Dunshea*
Affiliation:
Department of Primary Industries, 600 Sneydes Road, Werribee, Victoria, Australia, 3030
Dale E. Bauman
Affiliation:
Department of Animal Science, Cornell University, Ithaca, NY14853, USA
Elizabeth A. Nugent
Affiliation:
Department of Primary Industries, 600 Sneydes Road, Werribee, Victoria, Australia, 3030
Douglas J. Kerton
Affiliation:
Department of Primary Industries, 600 Sneydes Road, Werribee, Victoria, Australia, 3030
Raymond H. King
Affiliation:
Department of Primary Industries, 600 Sneydes Road, Werribee, Victoria, Australia, 3030
Ian McCauley
Affiliation:
Department of Primary Industries, 600 Sneydes Road, Werribee, Victoria, Australia, 3030
*
*Corresponding author: Professor Frank R. Dunshea, fax +61 3 9 742 0400, email [email protected]
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Abstract

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The aim of this study was to determine whether dietary supplementation with branched-chain amino acids, and the infusion of insulin and dextrose, would increase milk protein secretion in the sow. The experiment involved sixteen lactating sows fed either a normal lactation diet (162 g/kg crude protein, n 8) or a high-protein diet (230 g/kg crude protein, n 8) supplemented with branched-chain amino acids (valine, isoleucine and leucine). Sows were either infused with insulin and dextrose or not infused at all during mid (day 5–10) and late (day 17–22) lactation in a single reversal design. Blood samples were analysed for glucose, and the dextrose infusion rate was adjusted to maintain the blood glucose level within 15 % of pre-infusion levels. Milk (10·1 v. 11·1 kg/d; P=0·014) and\ lactose (628 v. 727 g/d; P=0·002) yield increased with insulin infusion, whereas milk protein content (5·0 % v. 5·5 %; P=0·007) was increased in diets supplemented with protein and branched-chain amino acids. Piglet growth was increased by feeding the higher-protein diet (237 v. 273 g/d; P=0·05) but not significantly increased by insulin infusion (245 v. 265 g/d; P=0·11). These effects were additive such that the combined treatment resulted in a 24 % (56 g/d; P<0·05) increase in piglet growth rate. These data demonstrate that increasing the dietary protein/branched-chain amino acid content can increase milk protein secretion but not milk yield. The infusion of insulin and dextrose increased milk and milk lactose yields, and tended to increase milk protein yield but not milk protein content. These effects are additive and translate to increased protein yield and piglet growth.

Keywords

PigLactationInsulinBranched-chain amino acidsProtein
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 3 , March 2005 , pp. 325 - 332
Copyright
Copyright © The Nutrition Society 2005

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