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Hepatic copper–and zinc-binding proteins in ruminants

1. Distribution of Cu and Zn among soluble proteins of livers of varying Cu and Zn content

Published online by Cambridge University Press:  24 July 2007

I Bremner  and
R. B Marshall
I Bremner
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen AB2 9SB
R. B Marshall
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen AB2 9SB
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Abstract

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1. A metal-binding fraction with a molecular weight of about 12000 in calf and sheep liver has been characterized as a metallothionein-like protein.

2. The combined concentrations of copper and zinc in the fraction (as μg/g liver) are a direct function of liver Zn concentration.

3. The relative proportions of Cu and Zn in the fraction are dependent on the Cu: Zn ratio in the liver.

4. These findings may be relevant to the mutual interaction between Cu and Zn.

Type
General Nutrition
Information
British Journal of Nutrition , Volume 32 , Issue 2 , September 1974 , pp. 283 - 291
Copyright
Copyright © The Nutrition Society 1974

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