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Gluconeogenesis from caecal propionate in the horse

Published online by Cambridge University Press:  07 March 2008

E. J. H. Ford
Affiliation:
Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston, South Wirral L64 7TH
H. A. Simmons
Affiliation:
Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston, South Wirral L64 7TH
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Abstract

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1. The production of propionate in the caecum of the horse has been measured in two Shetland-type ponies fitted with caecal and colonic cannulas and fed on hay or on hay and wheat bran. A continuous intracaecal infusion of 14C-labelled sodium propionate was used and samples were obtained from a cannula at the origin of the right ventral colon. A simultaneous intravenous infusion of [2-3H]glucose was used to measure total glucose entry.

2. On a hay diet which provided 177 kJ/kg body-weight per d, mean caecal propionate production was 19.6 (range 17.2–21.2) mg/h per kg body-weight and on a hay and wheat bran diet, which provided 187 KJ/kg body-weight per d, mean caecal propionate production was 34.0 (range 28.9–38.3) mg/h per kg body-weight.

3. Mean total glucose production (mg/h per kg body-weight) in one pony was 104 (range 100–110) and in the other 135 (range 123–153). Rates were not influenced by diet.

4. About 7% of total glucose production was derived from propionate produced in the caecum and this percentage was unaffected by diet or by individual animals.

Type
Papers on General Nutrition
Copyright
Copyright © The Nutrition Society 1985

References

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