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Fractional magnesium absorption is significantly lower in human subjects from a meal served with an oxalate-rich vegetable, spinach, as compared with a meal served with kale, a vegetable with a low oxalate content

Published online by Cambridge University Press:  09 March 2007

Torsten Bohn ,
Lena Davidsson ,
Thomas Walczyk  and
Richard F. Hurrell
Torsten Bohn
Affiliation:
Laboratory for Human Nutrition, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland
Lena Davidsson*
Affiliation:
Laboratory for Human Nutrition, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland
Thomas Walczyk
Affiliation:
Laboratory for Human Nutrition, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland
Richard F. Hurrell
Affiliation:
Laboratory for Human Nutrition, Institute of Food Science and Nutrition, Swiss Federal Institute of Technology, Zurich, Switzerland
*
*Corresponding author: Dr Lena Davidsson, fax +41 1 7045710, email [email protected]
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Abstract

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The aim of the present study was to evaluate Mg absorption from a test meal served with an oxalate-rich vegetable, spinach, as compared with a test meal served with a vegetable with a low oxalate content, kale. Mg absorption was measured by a stable-isotope technique based on extrinsic labelling of the test meals and faecal monitoring of the excreted isotope labels. Nine healthy adults participated in the study. The test meals were based on 100g phytate-free white bread, served with 300g spinach (6·6mmol oxalate; 0·7mmol 25Mg label added, 5·0mmol total Mg) or 300g kale (0·1mmol oxalate; 1·2mmol 26Mg label added, 4·8mmol total Mg). The test meals were served on days 1 and 3, at breakfast and lunch, using a cross-over design. The results from the present study demonstrated that apparent Mg absorption was significantly lower from the meal served with spinach (26·7 (sd 10·4) %) than the meal served with kale (36·5 (sd 11·8) %) (P=0·01). However, the lower fractional apparent Mg absorption from the test meal served with spinach can be assumed to be, at least partly, counterbalanced by the higher native Mg content of spinach as compared with kale. Although based on indirect evidence, i.e. not based on an evaluation of added (or removed) oxalic acid, the difference in Mg absorption observed in the present study is attributed to the difference in oxalic acid content between the two vegetables.

Keywords

Magnesium absorptionSpinachOxalateStable isotopesFaecal monitoring
Type
Research Article
Information
British Journal of Nutrition , Volume 91 , Issue 4 , April 2004 , pp. 601 - 606
Copyright
Copyright © The Nutrition Society 2004

References

Anderson, W, Hollins, JG & Bond, PS (1971) Composition of tea infusions examined in relation to association between mortality and water hardness. J Hyg Cambr 69, 1–15.CrossRefGoogle ScholarPubMed
Berg, W, Bothor, C, Pirlich, W & Janitzky, V (1986) Influence of magnesium on the absorption and excretion of calcium and oxalate ions. Eur Urol 12, 274–282.CrossRefGoogle ScholarPubMed
Brune, M, Rossander, L & Hallberg, L (1989) Iron absorption and phenolic compounds: importance of different phenolic structures. Eur J Clin Nutr 43, 547–557.Google ScholarPubMed
Coudray, C, Bellanger, J, Vermorel, M, Sinaud, S, Wils, D, Feillet-Coudray, C, Brandolini, M, Bouteloup-Demange, C & Rayssiguier, Y (2003 a) Two polyol, low digestible carbohydrates improve the apparent absorption of magnesium but not of calcium in healthy young men. J Nutr 133, 90–93.CrossRefGoogle Scholar
Coudray, C., Demigné, C & Rayssiguier, Y (2003 b) Effects of dietary fibers on magnesium absorption in animals and humans. J Nutr 133, 1–4.CrossRefGoogle Scholar
Drews, LM, Kies, C & Fox, HM (1979) Effect of dietary fiber on copper, zinc, and magnesium utilization by adolescent boys. Am J Clin Nutr 32, 1893–1897.CrossRefGoogle ScholarPubMed
Gillooly, M, Bothwell, TH, Torrance, JD, MacPhail, AP, Derman, DP, Bezwoda, WR, Mills, W, Charlton, RW & Mayet, F (1983) The effects of organic-acids, phytates and polyphenols on the absorption of iron from vegetables. Br J Nutr 49, 331–342.CrossRefGoogle ScholarPubMed
Hanes, DA, Weaver, CM, Heaney, RP & Wastney, M (1999) Absorption of calcium oxalate does not require dissociation in rats. J Nutr 129, 170–173.CrossRefGoogle ScholarPubMed
Hanson, CF, Frankos, VH & Thompson, WO (1989) Bioavailability of oxalic acid from spinach, sugar beet fibre and a solution of sodium oxalate consumed by female volunteers. Food Chem Toxicol 27, 181–184.CrossRefGoogle Scholar
Heaney, RP & Weaver, CM (1990) Calcium absorption from kale. Am J Clin Nutr 51, 656–657.CrossRefGoogle ScholarPubMed
Heaney, RP, Weaver, CM & Recker, RR (1988) Calcium absorbability from spinach. Am J Clin Nutr 47, 707–709.CrossRefGoogle ScholarPubMed
Hodgkinson, A (1977 a) Oxalate metabolism in animals and man. In Oxalic Acid in Biology and Medicine, pp. 160–192 [Hodgkinson, A, editor]. London: Academic Press.Google Scholar
Hodgkinson, A (1977 b) Oxalate content of foods and nutrition. In Oxalic Acid in Biology and Medicine, pp. 193–212 [Hodgkinson, A, editor]. London: Academic Press.Google Scholar
Holland, B, Welch, AA, Unwin, ID, Buss, DH, Paul, AA & Southgate, DAT (1994) The Composition of Foods, 5th ed. Cambridge, UK: Xerox Ventura.Google Scholar
Kelsay, JL & Prather, ES (1983) Mineral balances of human subjects consuming spinach in a low-fiber diet and in a diet containing fruits and vegetables. Am J Clin Nutr 38, 12–19.CrossRefGoogle Scholar
Lowenstein, FW & Stanton, MF (1986) Serum magnesium levels in the United States, 1971–1974. J Am Coll Nutr 5, 399–414.CrossRefGoogle ScholarPubMed
Lucarini, M, Di Lullo, G, Cappelloni, M & Lombardi-Boccia, G (2000) In vitro estimation of iron and zinc dialysability from vegetables and composite dishes commonly consumed in Italy: effect of red wine. Food Chem 70, 39–44.CrossRefGoogle Scholar
Sabatier, M, Arnaud, MJ, Kastenmayer, P, Rytz, A & Barclay, DV (2002) Meal effect on magnesium bioavailability from mineral water in healthy women. Am J Clin Nutr 75, 65–71.CrossRefGoogle ScholarPubMed
Sandberg, AS & Ahderinne, R (1986) HPLC method for determination of inositol triphosphates, tetraphosphates, pentaphosphates and hexaphosphates in foods and intestinal contents. J Food Sci 51, 547–550.CrossRefGoogle Scholar
Schwartz, R, Grunes, DL, Wentworth, RA & Wien, EM (1980) Magnesium absorption from leafy vegetables, intrinsically labeled with stable 26Mg. J Nutr 110, 1365–1371.CrossRefGoogle Scholar
Schwartz, R, Spencer, H & Welsh, JJ (1984) Magnesium absorption in human subjects from leafy vegetables, intrinsically labeled with stable 26Mg. Am J Clin Nutr 39, 571–576.CrossRefGoogle ScholarPubMed
Souci, SW, Fachmann, W & Kraut, H (1994) Food Composition and Nutrition Tables, 5th ed., Stuttgart, Germany: CRC Press.Google Scholar
Tabekhia, MM (1980) Total and free oxalates calcium, magnesium and iron contents of some fresh vegetables. Dtsch Lebensmitt Rundsch 76, 280–282.Google Scholar
Tahiri, M, Tressol, JC, Arnaud, J et al. , (2001) Five-week intake of short-chain fructo-oligosaccharides increases intestinal absorption and status of magnesium in postmenopausal women. J Bone Miner Res 16, 2152–2160.CrossRefGoogle ScholarPubMed
Toma, RB & Tabekhia, MM (1979) Trials to reduce soluble oxalates in home prepared spinach. Dtsch Lebensmitt Rundsch 75, 212–215.Google Scholar
Walczyk, T, Davidsson, L, Zavaleta, N & Hurrell, RF (1997) Stable isotope labels as a tool to determine the iron absorption by Peruvian school children from a breakfast meal. Fresenius J Anal Chem 359, 445–449.CrossRefGoogle Scholar
Weast, RC (1989) Handbook of Chemistry and Physics. Boca Raton, FL: CRC.Google Scholar
Weaver, MC & Heaney, RP (1991) Isotopic exchange of ingested calcium between labelled sources Evidence that ingested calcium does not form a common absorptive pool. Calcif Tissue Int 49, 244–247.CrossRefGoogle ScholarPubMed
Zarembski, PM & Hodgkinson, A (1962) Oxalic acid content of English diets. Br J Nutr 16, 627–634.CrossRefGoogle ScholarPubMed