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Fermentation of dietary fibre in the intestinal tract: comparison between man and rat

Published online by Cambridge University Press:  09 March 2007

Margareta Nyman ,
Nils-Georg Asp ,
John Cummings  and
Hugh Wiggins
Margareta Nyman
Affiliation:
Department of Food Chemistry, Chemical Centre, University of Lund, Lund, Sweden
Nils-Georg Asp
Affiliation:
Department of Food Chemistry, Chemical Centre, University of Lund, Lund, Sweden
John Cummings
Affiliation:
MRC Dunn Clinical Nutritional Laboratory, Old Addenbrookes Hospital, Cambridge
Hugh Wiggins
Affiliation:
MRC Dunn Clinical Nutritional Laboratory, Old Addenbrookes Hospital, Cambridge
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Abstract

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1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat.

2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4–29% of the neutral sugars were recovered in faeces.

3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost completely degraded. Of the xylose in wheat bran 45% (man) and 48% (rat) were recovered in faeces. However, the percentage excretion of glucose and arabinose from bran was higher in man.

4. A faecal glucan other than cellulose was identified in human faeces after guar gum, and has been provisionally identified as starch. No such glucan occurred in rat faeces.

5. A good correlation between the faecal bulking capacity in man and rat was seen (r 0.97, regression coefficient 0.56). Wheat bran had the best bulking capacity, while that of apple, cabbage, carrot and guar gum was less pronounced. Faecal bulking was inversely related to the amount of fibre which was water-soluble in each preparation.

6. It is concluded that this rat experimental model is useful for the prediction of fermentative breakdown and bulking capacity of dietary fibre in man. However, more comparative studies are needed to evaluate animal experiments regarding other physiological effects of dietary fibre.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 55 , Issue 3 , May 1986 , pp. 487 - 496
Copyright
Copyright © The Nutrition Society 1986

References

REFERENCES

Asp, N.-G., Johansson, C.-G., Hallmer, H. & Siljestrom, M. (1983). Journal of Agricultural and Food Chemistry 31, 476–482.CrossRefGoogle Scholar
Bjorck, I., Nyman, M. & Asp, N.-G. (1984). Cereal Chemistry 61, 174–179.Google Scholar
Bjorck, I., Nyman, M., Pedersen, B., Siljestrom, M., Asp, N.-G. & Eggum, B. O. (1986). Journal of Cereal Science 4, 1–11.CrossRefGoogle Scholar
Cummings, J. H. (1981). British Medical Bulletin 37, 65–70.CrossRefGoogle Scholar
Cummings, J. H. (1982). In Dietary Fiber in Health and Disease, pp. 9–22 [Vahouny, G. and Kritchevsky, D., editors]. New York: Plenum Press.CrossRefGoogle Scholar
Cummings, J. H. (1983 a).Lancet i, 1206–1209.CrossRefGoogle Scholar
Cummings, J. H. (1983 b). In Nutrition and the Intestinal Flora, pp. 77–86 [Hallgren, B., editor]. Uppsala, Sweden: Almqvist & Wiksell.Google Scholar
Cummings, J. H.& Branch, W. J. (1982). In Dietary Fiber in Health and Disease, pp. 313–325 [Vahouny, G. and Kritchevsky, D., editors]. New York: Plenum Press.CrossRefGoogle Scholar
Cummings, J. H., Southgate, D. A. T., Branch, W. J., Houston, H., Jenkins, D. J. A.& James, W. P. T. (1978). Lancet i, 5–8.CrossRefGoogle Scholar
Cummings, J. H., Southgate, D. A. T., Branch, W. J., Wiggins, H. S., Houston, H., Jenkins, D. J. A., Jivraj, T. & Hill, M. J. (1979). British Journal of Nutrition 41, 477–485.CrossRefGoogle Scholar
Dekker, R. F. H. & Richards, G. N. (1973). Journal of the Science of Food and Agriculture 24, 375–379.CrossRefGoogle Scholar
Dintzis, F. R., Legg, L. M., Deatherage, W. L., Baker, F. L., Inglett, G. E., Jacob, R. A, Reck, S. J., Munoz, J. M., Klevay, L. M., Sandstead, H. H.& Shuey, W. C. (1979). Cereal Chemistry 56, 123–127.Google Scholar
Englyst, H., Wiggins, H. S.& Cummings, J. H. (1982). Analyst 107, 307–318.CrossRefGoogle Scholar
Heller, S. N., Hackler, L. R., Rivers, J. M., Van Soest, P. J., Roe, D. A, Lewis, B. A. & Robertson, J. (1980). American Journal of Clinical Nutrition 33, 1734–1744.CrossRefGoogle Scholar
Johansson, C.-G., Siljestrom, M.& Asp, N.-G. (1984). Zeitschrqt fur Lebensmittel Untersuchung und Forschung 179, 24–28.CrossRefGoogle Scholar
Keys, J. E., Van Soest, P. J. & Young, E. P. (1970). Journal of Animal Science 31, 1172–1177.CrossRefGoogle Scholar
McNeil, N. I., Cummings, J. H. & James, W. P. T. (1978). Gut 19, 819–822.CrossRefGoogle Scholar
Mason, V. C. & Palmer, R. (1973). Acta Agriculturae Scandinavica 23, 141–150.CrossRefGoogle Scholar
Nyman, M. & Asp, N.-G. (1982). British Journal of Nutrition 47, 357–366.CrossRefGoogle Scholar
Nyman, M. & Asp, N.-G. (1985 a). Scandinavian Journal of Gastroenterology 20, 887–895.CrossRefGoogle Scholar
Nyman, M. & Asp, N.-G. (1985 b). British Journal of Nutrition M, 54 635–643.CrossRefGoogle Scholar
Nyman, M., Asp, N.-G., Pedersen, B. & Eggum, B. O. (1985). Journal of Cereal Science 3 207–219.CrossRefGoogle Scholar
Paul, A. A. & Southgate, D. A. (1978). McCance and Widdowson's The Composition of Foods. London: H.M. Stationery Office.Google Scholar
Rotenberg, S., Eggum, B. O., Hegediis, M. & Jacobsen, I. (1982). Acta Agriculfurae Scandinuvicu 32, 309–319.CrossRefGoogle Scholar
Savage, D. C. (1983). In Proceedings of Fibre in Human and Animal Nutrition Symposium, pp. 125–129 [Wallace, G. and Bell, L., editors]. Wellington, New Zealand: The Royal Society of New Zealand.Google Scholar
Sawardeker, J. S., Sloneker, J. H. & Jeanes, A. (1965). Analytical Chemistry 37, 1602– 1604.CrossRefGoogle Scholar
Siljeström, M. & Asp, N.-G. (1985). Zeitschrift fur Lebensmittel Untersuchung und Forschung 181, 4–8.CrossRefGoogle Scholar
Theander, O. & Aman, P. (1979). Swedish Journal of Agricultural Research 9, 97–106.Google Scholar
Theander, O. & Aman, P. (1981). In The Analysis of Dietary Fiber in Food, pp. 51–70 [James, W. P. T. and Theander, O., editors]. New York and Basel: Marcel Dekker Inc.Google Scholar
Vahouny, G. & Kritschevsky, D. [editors] (1982). Dietary Fiber in Health and Disease. New York: Plenum Press.CrossRefGoogle Scholar
Van Dokkum, W., Pikaar, N. A. & Thissen, J. T. N. M. (1983). British Journal of Nutrition 50, 61–74.CrossRefGoogle Scholar
Van soest, P. J., Jeraci, J., Foose, T., Wrick, K. & Ehle, F. (1983). In Proceedings of Fibre in Human and Anima Nutrition Symposium, pp. 75–80 [Wallace, G. and Bell, L., editors]. Wellington, New Zealand: The Royal Society of New Zealand.Google Scholar
Wyman, J. B., Heaton, K. W., Manning, A. P. & Wicks, A. C. B. (1976). American Journal of Clinical Nutrition 29, 1474–1479.CrossRefGoogle Scholar