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Evaluation of role of concentration and molecular weight of oat β-glucan in determining effect of viscosity on plasma glucose and insulin following an oral glucose load

Published online by Cambridge University Press:  09 March 2007

P. J. Wood ,
M. U. Beer  and
G. Butler
P. J. Wood*
Affiliation:
Agriculture and Agri-Food Canada, Southern Crop Protection and Food Research Centre, 93 Stone Road West, Guelph, Ontario, N1G 2W1, Canada
M. U. Beer
Affiliation:
Novartis Nutrition Research AG, CH-3176, Neuenegg, Switzerland
G. Butler
Affiliation:
Agriculture and Agri-Food Canada, Eastern Cereal and Oilseed Research Centre, Ottawa, Ontario, K1A 0C6, Canada
*
*Corresponding author: Dr Peter J. Wood, fax +1 519 837 9472, email [email protected]
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Abstract

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Data from clinical studies established that there was an inverse linear relationship between measures of postprandial blood glucose and insulin responses to an oral glucose load, consumed in a drink, and the logarithm of viscosity of the drink. These data have been re-analysed using concentration and molecular weight as the dependent variables. Molecular weight (M) of the β-glucans used was determined using high-performance size exclusion chromatography equipped with a triple detector system of right angle light scattering, viscometry and refractive index. A significant relationship between changes in peak blood glucose and a combination of logarithm of the concentration and logarithm of M was found.

Keywords

-GlucanMolecular weightGlycaemic response
Type
Short communication
Information
British Journal of Nutrition , Volume 84 , Issue 1 , July 2000 , pp. 19 - 23
Copyright
Copyright © The Nutrition Society 2000

References

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