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Energy supplementation reverses changes in the basal metabolic rates of chronically undernourished individuals

Published online by Cambridge University Press:  09 March 2007

M. J. Soares ,
R. N. Kulkarni ,
L. S. Piers ,
M. Vaz  and
P. S. Shetty
M. J. Soares
Affiliation:
Nutrition Research Centre, Department of Physiology, St John's Medical College, Bangalore 560 034, India
R. N. Kulkarni
Affiliation:
Nutrition Research Centre, Department of Physiology, St John's Medical College, Bangalore 560 034, India
L. S. Piers
Affiliation:
Nutrition Research Centre, Department of Physiology, St John's Medical College, Bangalore 560 034, India
M. Vaz
Affiliation:
Nutrition Research Centre, Department of Physiology, St John's Medical College, Bangalore 560 034, India
P. S. Shetty
Affiliation:
Nutrition Research Centre, Department of Physiology, St John's Medical College, Bangalore 560 034, India
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Abstract

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The objective of the present study was to examine the influence of energy supplementation and its cessation thereafter on the basal metabolic rates (BMR) of chronically undernourished individuals. Seven apparently healthy males were supplemented daily with 3.35 MJ (15 g protein, 35 g fat, 105 g carbohydrate) for 12 weeks. The average gain in body-weight was 1.9 kg (body fat, 58%; fat-free mass (FFM), 42%). The rise in BMR exceeded that accounted for by the increases in FFM during the 12 weeks of supplementation and was attributed to increases in the amount and activity of the visceral tissue as well as to an added cost of lipogenesis. At 12 weeks after cessation of the supplement, body-weights and FFM had decreased to presupplementation levels. BMR at this stage were significantly lower than at the 12th week of supplementation, when expressed per kg FFM or when adjusted for FFM using an analysis of covariance. These results suggest an increase in the metabolic efficiency during this negative energy balance period. The study demonstrates that, in the chronically undernourished, the changes in BMR are reversible and, hence, physiologically important to the process of adaptation to low-energy intakes.

Keywords

Basal metabolic rateBody compositionMetabolic efficiencyChronic undernutritionEnergy supplementation
Type
Metabolic Effects of Feeding
Information
British Journal of Nutrition , Volume 68 , Issue 3 , November 1992 , pp. 593 - 602
Copyright
Copyright © The Nutrition Society 1992

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