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Effects of l-carnitine supplementation on milk production, litter gains and back-fat thickness in sows with a low energy and protein intake during lactation

Published online by Cambridge University Press:  08 March 2007

A. Ramanau ,
H. Kluge  and
K. Eder
A. Ramanau
Affiliation:
Institute of Nutritional Sciences, Martin-Luther University Halle-, Wittenberg, Germany
H. Kluge
Affiliation:
Institute of Nutritional Sciences, Martin-Luther University Halle-, Wittenberg, Germany
K. Eder*
Affiliation:
Institute of Nutritional Sciences, Martin-Luther University Halle-, Wittenberg, Germany
*
*Corresponding author: Dr K. Eder, fax +49345 55 21 724, email [email protected]
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Abstract

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The present study investigated the effect of l-carnitine supplementation during pregnancy (125 mg/d) and lactation (250 mg/d) on milk production, litter gains and back-fat thickness in sows fed a low-energy and low-protein diet during lactation. Sows supplemented with l-carnitine produced more milk on days 11 and 18 of lactation (+18 %; P<0·05) and had higher litter gains during suckling (+20 %; P<0·01) than control sows. Loss of body weight during lactation was similar in both groups, but sows supplemented with l-carnitine had a greater reduction of back-fat thickness (+45 %; P<0·05) during lactation than control sows. In conclusion, this study shows that l-carnitine increases milk production and litter gains in sows in a strongly negative energy and N balance, and enhances body fat mobilisation.

Keywords

l-CarnitineSowLactationMilk productionEnergy balance
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 5 , May 2005 , pp. 717 - 721
Copyright
Copyright © The Nutrition Society 2005

References

Aherne, FX & Williams, IH (1992) Nutrition for optimizing breed herd performance. Vet Clin North Am Food Anim Pract 8, 589–608.CrossRefGoogle ScholarPubMed
Association of Official Analytical Chemists (1990) Official Methods of Analysis, [Helrich, K, editors]. 15th ed. Arlington, VA: Association of Analytical Chemists.Google Scholar
Bassler, R & Buchholz, H (1993) Methodenbuch Band III. Die Chemische Untersuchung von Futtermitteln, Vol. 3. Ergänzungslieferung Darmstadt, Germany VDLUFA-VerlagGoogle Scholar
Bremer, J (1963) Carnitine in intermediary metabolism – the biosynthesis of palmitoylcarnitine by cell subfractions. J Biol Chem 238, 2774–2779.CrossRefGoogle ScholarPubMed
Eder, K, Peganova, S & Kluge, H (2001a) Studies on the tryptophan requirement of piglets. Arch Anim Nutr 55, 281–297.Google ScholarPubMed
Eder, K, Ramanau, A & Kluge, H (2001b) Effect of l -carnitine supplementation on performance parameters in gilts and sows. J Anim Physiol Anim Nutr 85, 73–80.CrossRefGoogle ScholarPubMed
Fontaine, J, Bech-Andersen, S, Bütikofer, U, De Froidmont-Görtz, I (1998) Determination of tryptophan in feed by HPLC – development of an optimal hydrolysis and extraction procedure by the EU Commission DG XII in three international collaborative studies. Agribiol Res 51, 97–108.CrossRefGoogle Scholar
Gesellschaft für Ernährungsphysiologie (Ausschuβ für Bedarfsnormen) (1987) Energie- und Nährstoffbedarf landwirtschaftlicher Nutztiere, Vol. 4, Schweine Frankfurt/Main, Germany DLG-VerlagGoogle Scholar
Heo, K, Odle, J, Han, IK, Cho, W, Seo, S, Van Heugten, E & Pilkington, DH (2000) Dietary l -carnitine improves nitrogen utilisation in growing pigs fed low energy, fat-containing diets. J Nutr 130, 1809–1814.Google ScholarPubMed
Kirchgessner, M, Schneider, R & Paulicks, BR (1992) Milchleistung sowie Milchfett- und -energiegehalte bei Sauen mit unterschiedlicher Methioninversorgung. J Anim Physiol Anim Nutr 68, 244–253.CrossRefGoogle Scholar
McGarry, JD & Foster, DW (1976) An improved and simplified radioisotopic assay for the determination of free and esterified carnitine. J Lip Res 17, 277–281.CrossRefGoogle ScholarPubMed
Musser, RE, Goodband, RD, Tokach, MD, Owen, KQ, Nelssen, JL, Blum, SA, Dritz, SS & Civis, CA (1999) Effects of l -carnitine fed during gestation and lactation on sow and litter performance. J Anim Sci 77, 3289–3295.CrossRefGoogle ScholarPubMed
National Research Council (1998) Nutrient Requirements of Swine 10th rev ed. Washington National Academy PressGoogle Scholar
Noblet, J, Etienne, M, Dourmad, J-Y (1998) Energetic efficiency of milk production. In The Lactating Sow, p. 113 [Verstegen, MWA, Moughan, PJ, Schrama, JW, editors]. Wageningen, The Netherlands: Wageningen Pers.Google Scholar
Owen, KQ, Ji, H, Maxwell, CV, Nelssen, JL, Goodband, RD, Tokach, MD, Tremblay, GC & Koo, IS (2001a) Dietary l -carnitine suppresses mitochondrial branched-chain keto acid dehydrogenase activity and enhances protein accretion and carcass characteristics of swine. J Anim Sci 79, 3104–3112.CrossRefGoogle ScholarPubMed
Owen, KQ, Nelssen, JL, Goodband, RD, Tokach, MD & Friesen, KG (2001b) Effect of dietary l -carnitine on growth performance and body composition in nursery and growing-finishing pigs. J Anim Sci 79, 1509–1515.CrossRefGoogle ScholarPubMed
Owen, KQ, Nelssen, JL, Goodband, RD, Weeden, TL & Blum, SA (1996) Effect of l -carnitine and soybean oil on growth performance and body composition of early-weaned pigs. J Anim Sci 74, 1612–1619.CrossRefGoogle ScholarPubMed
Pettigrew, JE (1995) The influence on substrate supply on milk production in the sow. In Manipulating Pig Production, V, p. 101 [Hennessy, DP, Cranwell, PD, editors]. Werribee, Victoria, Australia: Australian Pig Science Association.Google Scholar
Ramanau, A, Kluge, H, Spilke, J & Eder, K (2002) Reproductive performance of sows supplemented with dietary l -carnitine over three reproductive cycles. Arch Anim Nutr 56, 287–296.Google ScholarPubMed
Ramanau, A, Kluge, H, Spilke, J & Eder, K (2004) Supplementation of sows with l -carnitine during pregnancy and lactation improves growth of the piglets during the suckling period through increased milk production. J Nutr 134, 86–92.CrossRefGoogle Scholar
Rozeboom, DW, Pettigrew, JE, Moser, RL, Cornelius, SGEl, Kandelgy, SM (1996) Influence of gilt age and body composition at first breeding on sow reproductive performance and longevity. J Anim Sci 74, 138–150.CrossRefGoogle ScholarPubMed
Van den, Brand, H, Heetkamp, MJW, Soede, NM, Schrama JW, Kemp, B (2000) Energy balance of lactating primiparous sows as affected by feeding level and dietary energy source. J Anim Sci 78, 1520–1528.CrossRefGoogle Scholar