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Effects of infusions of lysine, leucine and ammonium chloride into the hepatic portal vein of chickens on voluntary food intake

Published online by Cambridge University Press:  09 March 2007

Audrey A. Rusby  and
J. M. Forbes
Audrey A. Rusby
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds LS2 9JT
J. M. Forbes
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds LS2 9JT
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Abstract

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1. Adolescent cockerels of a laying strain were prepared with catheters whose tip lay in the hepatic portal vein, to study the effect of 3-h infusions of nutrients on food intake.

2. Lysine, infused into the hepatic portal vein at rates of 150–450 mg/3 h reduced 3-h food intake by up to 58%, for a period of 6 h in previously starved birds, but had no effect on birds allowed free access to food. Infusions made into the jugular vein had no effect, suggesting a role for the liver in monitoring lysine levels.

3. Portal infusion of leucine had a delayed effect while ammonium chloride, infused at isomolar rates to those of the lysine infusions, had very little effect on intake.

4. The results support the concept of liver sensitivity to amino acids, but the mode of action is not clear; it appears not to be via the effects of ammonia.

Type
General Nutrition papers
Information
British Journal of Nutrition , Volume 58 , Issue 2 , September 1987 , pp. 325 - 331
Copyright
Copyright © The Nutrition Society 1987

References

REFERENCES

Agricultural Research Council (1975). Nutrient Requirements of Farm Animals no. 1, Poultry. Farnham Royal: Commonwealth Agricultural Bureaux.Google Scholar
Almquist, H. J. (1954). Archives of Biochemistry and Biophysics 52, 197.CrossRefGoogle Scholar
Ashley, D. V. M. & Anderson, G. H. (1977). Federation Proceedings 36, 4665.Google Scholar
Gandal, C. P. (1969). Federation Proceedings 28, 1553–1554.Google Scholar
Harper, A. E., Benevenga, N. J. & Wohlhueter, R. M. (1970). Physiological Reviews 50, 429–558.CrossRefGoogle Scholar
Leung, P. M. B. & Rogers, Q. R. (1974). Federation Proceedings 33, 651.Google Scholar
Mayer, J., Vitale, J. J. & Bates, M. W. (1951). Nature 167, 562–563.CrossRefGoogle Scholar
Mellinkoff, S. M., Frankland, M., Boyle, D. & Greipel, M. (1955). Journal of Applied Physiology 8, 535–538.CrossRefGoogle Scholar
Munro, H. N. (1965). Proceedings of the Nutrition Society 24, 209–215.CrossRefGoogle Scholar
Panksepp, J. & Booth, D. A. (1971). Nature 233, 341–342.CrossRefGoogle Scholar
Peng, Y. & Harper, A. E. (1969). American Journal of Physiology 217, 1441–1445.CrossRefGoogle Scholar
Prior, R. L., Clifford, A. J., Gibson, G. E. & Visek, W. J. (1971). American Journal of Physiology 221, 432–436.CrossRefGoogle Scholar
Rezek, M. & Novin, D. (1977). American Journal of Physiology 232, E119.Google Scholar
Rusby, A. A. (1982). Journal of Physiology 330, 19P.Google Scholar
Rusby, A. A. (1985). The role of the liver in the control of food intake in the domestic chicken. PhD Thesis, University of Leeds.Google Scholar
Russek, M. (1970). Federation Proceedings 29, 658.Google Scholar
Russek, M. (1971). In Neuroscience Research, pp. 213–282 [Ehrenpreis, S., editor]. New York: Raven Press.CrossRefGoogle Scholar
Sanahuja, J. C., Rio, M. E. & Lede, M. N. (1965). Journal of Nutrition 86, 424–432.CrossRefGoogle Scholar
S.A.S.(1982). S.A.S. User's Guide: Statistics. Cary, North Carolina: S.A.S. Institute.Google Scholar
Smith, C. J. V. & Brighit-Taylor, B. (1974). Poultry Science 53, 1720–1724.CrossRefGoogle Scholar
Shurlock, T. G. H. (1980). The role of the gastrointestinal tract and the liver in short tern food intake regulation in the domestic chicken. PhD Thesis, University of Leeds.Google Scholar
Shurlock, T. G. H. & Forbes, J. M. (1981). British Poultry Science 22, 333–346.CrossRefGoogle Scholar
Shurlock, T. G. H. & Forbes, J. M. (1984). British Poultry Science 25, 303–308.CrossRefGoogle Scholar
Stephens, D. B. & Baldwin, B. A. (1974). Physiology and Behaviour 12, 923–929.CrossRefGoogle Scholar
Tobin, G. & Boorman, K. N. (1979). British Journal of Nutrition 41, 157–167.CrossRefGoogle Scholar
Vanderweele, D. A., Skoog, D. R. & Novin, D. (1976). American Journal of Physiology 231, 1655–1659.CrossRefGoogle Scholar
Yin, T. H., Tsai, W. H., Barone, F. C. & Wayner, M. J. (1979). Physiology and Behaviour 22, 1207–1210.CrossRefGoogle Scholar