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Effects of guar gum on plasma urea, insulin and glucose in the growing pig

Published online by Cambridge University Press:  09 March 2007

Kjell MalmlÖf
Affiliation:
Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
Carlos Simoes Nunes
Affiliation:
INRA, Laboratoire de Physiologie de la Nutrition, Centre National de Recherches Zootechniques, 78350 Jouy-en-Josas, France
Stefan Askbrant
Affiliation:
Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
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Abstract

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1. Six growing pigs fitted with portal and arterial blood cannulas were given a barley-fishmeal diet, either alone or supplemented with guar gum at 60 g/kg basal diet. Blood samples were taken during 8 h following test meals given at 08.00 hours.

2. Ingestion of the guar-gum-supplemented diet appeared to increase systematically portal and arterial levels of plasma urea. At peak values, 4 and 5 h after the test meal, this effect was statistically significant (P <0.05).

3. Irrespective of which diet was given, portal and arterial blood samples, withdrawn at the same time, were found to have about the same concentration of urea. This was found throughout the 8 h studied and implies that no net exchange of urea between the circulation and the gastrointestinal tract, as a whole, took place.

4. In the time-period 30–60 min following the test meal, guar gum significantly reduced the postprandial hyperglycaemia and hyperinsulinaemia in portal blood.

Type
Dietary Polysaccharides: Metabolic Effects
Copyright
Copyright © The Nutrition Society 1989

References

Fuller, M., Weekes, T., Cadenhead, A. & Bruce, J. (1977). The protein-sparing effect of carbohydrate: the role of insulin. British Journal of Nutrition 38, 489496.Google Scholar
Herbert, V., Lau, K., Gottlieb, C. & Bleicher, S. (1965). Coated charcoal immunoassay of insulin. Journal of Clinical Endocrinology and Metabolism 25, 13751384.Google Scholar
Jenkins, D., Leeds, A., Gassull, M., Cochet, B. & Alberti, G. (1977). Decrease in postprandial insulin and glucose concentrations by guar and pectin. Annals of Internal Medicine 86, 2023.Google Scholar
Jenkins, D., Wolever, T., Leeds, A., Gassull, M., Haisman, P., Dilawari, J., Goff, D., Metz, G. & Alberti, G. (1978). Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity. British Medical Journal i, 13921394.Google Scholar
Kahn, R., Baird, K., Flier, J., Grunfeld, C., Harmon, J., Harrison, L., Karlsson, A., Kasuga, M., King, G., Lang, U., Podskalny, J. & Obberghen, E. (1981). Insulin receptors, receptor antibodies and the mechanisms of insulin action. Recent Progress in Hormone Research 37, 477533.Google Scholar
Low, A. G. & Rainbird, A. L. (1984). Effect of guar gum on nitrogen secretion into isolated loops of jejunum in conscious growing pigs. British Journal of Nutrition 52, 499505.Google Scholar
Malmlöf, K. (1987). Porto-arterial plasma concentration differences of urea and ammonia-nitrogen in growing pigs given high- and low-fibre diets. British Journal of Nutrition 57, 439446.Google Scholar
Morgan, L., Goulder, T., Tsiolakis, D., Marks, V. & Alberti, K. G. M. M. (1979). The effect of unabsorbable carbohydrate on gut hormones. Diabetologia 17, 8589.Google Scholar
Rainbird, A. L., Low, A. G. & Zebrowska, T. (1984). Effect of guar gum on glucose and water absorption from isolated loops of jejunum in conscious growing pigs. British Journal of Nutrition 52, 489498.Google Scholar
Rérat, A., Vaugelade, P. & Villiers, P. (1980). A new method for measuring the absorption of nutrients in the pig: critical examination. In Current Concepts of Digestion and Absorption in Pigs, pp. 177214 [A., G., Low, and I. G. Partridge, editors]. Reading: National Institute for Research in Dairying.Google Scholar
Romsos, D., Leveille, G. & Allee, G. (1971). Alloxan diabetes in the pig (Sus domesticus). Response to glucose, tolbutamide and insulin administration. Comparative Biochemistry and Physiology 40A, 557568.Google Scholar
Sambrook, I. E. & Rainbird, A. L. (1985). The effect of guar gum and level and source of dietary fat and glucose tolerance in growing pigs. British Journal of Nutrition 54, 2735.Google Scholar
SAS, Institute Inc. (1985). SAS User's Guide, Statistics, 5th ed. Cary, NC: SAS Institute Inc.Google Scholar
Technicon, Instruments Co. (1972). Clinical Method no. 01. Tarrytown, New York: Technicon Instruments Co.Google Scholar
Technicon, Scandinavia AB (1979). Method no. 78–5R. Stockholm: Technicon Scandinavia AB.Google Scholar