Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-25T06:53:23.705Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of exogenous glucose on glucose metabolism in the lactating goat in vivo

Published online by Cambridge University Press:  09 March 2007

N. Chaiyabutr ,
Anne Faulkner  and
M. Peaker
N. Chaiyabutr
Affiliation:
Hannah Research Institute, Ayr KA6 5HL, Scotland
Anne Faulkner
Affiliation:
Hannah Research Institute, Ayr KA6 5HL, Scotland
M. Peaker
Affiliation:
Hannah Research Institute, Ayr KA6 5HL, Scotland
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Glucose turnover in fed and 48 h-starved lactating goats was determined during a glucose load of 500 μmol/min using a continuous infusion of [U-14C]- and [3-3H]glucose.

2. Endogenous rates of irreversible glucose turnover (i.e. total rates of irreversible glucose turnover minus the rate of exogenous glucose supply) were depressed during glucose loading by 14 and 62% in the fed and starved animals respectively.

3. Plasma glucose concentrations increased significantly by 57 and 88% in the fed and starved goats respectively. Plasma insulin concentrations increased by 108 and 128% in the fed and starved animals respectively.

4. Milk yields increased significantly (41%) in the starved animals during glucose loading, but were unaffected in fed animals.

5. In both the fed and 48 h-starved goats, mammary glucose metabolism via glycolysis and the pentose phosphate pathway appeared to be stimulated by glucose loading.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 49 , Issue 1 , January 1983 , pp. 159 - 165
Copyright
Copyright © The Nutrition Society 1983

References

Annison, E. F., Linzell, J. L. & West, C. E. (1968). J. Physiol., Lond. 197, 445.CrossRefGoogle Scholar
Baird, G. D., Lomax, M. A., Symonds, H. W. & Shaw, S. R. (1980). Biochem. J. 186, 47.CrossRefGoogle Scholar
Bartley, J. C. & Black, A. L. (1966). J. Nutr. 89, 317.CrossRefGoogle Scholar
Bergman, E. N. (1973). Cornell Vet. 63, 341.Google Scholar
Blatchford, D. R. & Peaker, M. (1982). Q. Jl exp. Physiol. (In the Press.)Google Scholar
Chaiyabutr, N., Faulkner, A. & Peaker, M. (1980). Biochem. J. 186, 301.CrossRefGoogle Scholar
Chaiyabutr, N., Faulkner, A. & Peaker, M. (1982). Br. J. Nutr. 46, 87.CrossRefGoogle Scholar
Judson, G. J. & Leng, R. A. (1973). Br. J. Nutr. 29, 159.CrossRefGoogle Scholar
Linzell, J. L. (1960). J. Physiol., Lond. 153, 481.CrossRefGoogle Scholar
Linzell, J. L. (1967). J. Physiol., Lond. 190, 347.CrossRefGoogle Scholar
Linzell, J. L. & Peaker, M. (1971). J. Physiol., Lond. 216, 717.CrossRefGoogle Scholar
Lomax, M. A., Baird, G. D., Mallinson, C. B. & Symonds, H. W. (1979). Biochem. J. 1800, 281.CrossRefGoogle Scholar
Mepham, T. B. & Linzell, J. L. (1974). J. Dairy Res. 41, 111.CrossRefGoogle Scholar
Reid, I. M., Stark, A. J. & Isenor, R. N. (1977). J. comp. Path. 87, 241.CrossRefGoogle Scholar
Rook, J. A. F. (1979). Proc. Nutr. Soc. 38, 309.CrossRefGoogle Scholar
Treacher, R. J., Baird, G. D. & Young, J. L. (1976). Biochem. J. 158, 127.CrossRefGoogle Scholar
West, C. E. & Passey, R. F. (1967). Biochem. J. 102, 58.CrossRefGoogle Scholar