Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-23T03:56:00.478Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of somatotropin administration and duodenal infusion of methionine and lysine on lactational performance and nutrient flow to the small intestine

Published online by Cambridge University Press:  09 March 2007

J. M. Aldrich ,
L. D. Muller  and
G. A. Varga
J. M. Aldrich
Affiliation:
Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
L. D. Muller
Affiliation:
Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
G. A. Varga
Affiliation:
Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Lack of sufficient methionine and lysine delivered post-ruminally may limit milk production response to bovine somatotropin (bST). To test this hypothesis, four Holstein cows fitted with rumen and duodenal cannulas were used in a 4 × 4 Latin square design with 14 d periods. Treatments were: (1) control, (2) continuous duodenal infusion of 8 g methionine and 24 g lysine/d, (3) injection of 25 mg bST/d and (4) infusion of methionine and lysine plus injection of bST. Infusion of amino acids led to trends for small increases in milk (3%), fat (5.5%), and protein (3.7%) yield. Larger and significant increases (8.7, 14 and 6.9% for milk, fat and protein yield respectively) were achieved with bST administration which also increased milk fat content. Plasma levels of urea-N and essential amino acids were reduced with bST. Duodenal nutrient flow was generally unaffected by treatment. The production response to bST was not enhanced in cows producing an average of 34 kg milk when provided additional methionine and lysine post-ruminally in this short-term study.

Keywords

MethionineLysineSomatotropinNutrient flow
Type
Nutrient Interations and Lactation
Information
British Journal of Nutrition , Volume 69 , Issue 1 , January 1993 , pp. 49 - 58
Copyright
Copyright © The Nutrition Society 1993

References

REFERENCES

Association of Official Analytical Chemists (1980). Official Methods of Analysis, 12th ed. Washington, DC: Association of Official Analytical Chemists.Google Scholar
Bauman, D. E., Eppard, P. J., DeGeeter, M. J. & Lanza, G. M. (1985). Responses of high producing dairy cows to long-term treatment with pituitary somatotropin and recombinant somatotropin. Journal of Dairy Science 68, 1352–1362.CrossRefGoogle ScholarPubMed
Bauman, D. E. & McCutcheon, S. N. (1986). The effects of growth hormone and prolactin on metabolism. In Control of Digestion and Metabolism in Ruminants, pp. 436–455 [Milligan, L. D., Grovum, W. L., and Dobson, A., editors]. New Jersey: Prentice Hall.Google Scholar
Bitman, J., Wood, D. L., Tyrrell, H. F., Bauman, D. E., Peel, C. J., Brown, A. C. G. & Reynolds, P. J. (1984). Blood and milk lipid responses induced by growth hormone administration in lactating cows. Journal of Dairy Science 67, 2873 2880.CrossRefGoogle ScholarPubMed
Botts, R. L., Hemken, R. W. & Bull, L. S. (1979). Protein reserves in lactating dairy cow. Journal of Dairy Science 62, 433–440.CrossRefGoogle ScholarPubMed
Chaney, A. L. & Marbach, E. P. (1962). Modified reagents for determination of urea and ammonia. Clinical Chemistry 8, 130–132.CrossRefGoogle ScholarPubMed
Christopherson, S. W. & Glass, R. L. (1969). Preparation of milk fat methyl esters by alcoholysis in an essential nonalcoholic solution. Journal of Dairy Science 52, 1289–1290.CrossRefGoogle Scholar
De Boer, G. & Kennelly, J. J. (1989 a). Effect of somatotropin injection and dietary protein concentration on milk yield, and kinetics of hormones in dairy cows. Journal of Dairy Science 66, 419–428.CrossRefGoogle Scholar
De Boer, G. & Kennelly, J. J. (1989 b). Effect of somatotropin and dietary protein concentration on hormone and metabolite responses to single injections of hormones and glucose. Journal of Dairy Science 72, 429–435.CrossRefGoogle ScholarPubMed
Donkin, S. S., Varga, G. A., Sweeney, T. F. & Muller, L. D. (1989). Rumen-protected methionine and lysine: effects on animal performance, milk protein yield, and physiological measures. Journal of Dairy Science 72, 1484–1491.CrossRefGoogle ScholarPubMed
Eisemann, J. H., Hammond, A. C., Bauman, D. E., Reynolds, P. J., McCutcheon, S. N., Tyrrell, H. F. & Haaland, G. L. (1986). Effect of bovine growth hormone administration on metabolism of growing Hereford heifers: protein and lipid metabolism and plasma concentrations of metabolites and hormones. Journal of Nutrition 116, 2504–2515.CrossRefGoogle ScholarPubMed
Glenn, B. P., Varga, G. A., Huntington, G. B. & Waldo, D. R. (1989). Duodenal nutrient flow and digestibility in Holstein steers fed formaldehyde- and formic acid-treated alfalfa or orchardgrass silage at two intakes. Journal of Animal Science 67, 513–528.CrossRefGoogle ScholarPubMed
Hart, S. P. & Polan, C. E. (1984). Simultaneous extraction and determination of ytterbium and cobalt ethylenediaminetetraacetate complex in feces. Journal of Dairy Science 67, 888–892.CrossRefGoogle Scholar
Lormore, M. J., Muller, L. D., Deaver, D. R. & Griel, L. C. Jr (1990). Early lactation responses of dairy cows administered bovine somatotropin and fed diets high in energy and protein. Journal of Dairy Science 73, 3237–3247.CrossRefGoogle Scholar
Lynch, G. L., Klusmeyer, T. H., Cameron, M. R., Clark, J. H. & Nelson, D. R.. (1991). Effects of somatotropin and duodenal infusion of amino acids on nutrient passage to duodenum and performance of dairy cows. Journal of Dairy Science 74, 3117–3127.CrossRefGoogle ScholarPubMed
McDowell, G. H., Hart, I. C., Bines, J. A., Lindsay, D. B. & Kirby, A. C. (1987). Effects of pituitary-derived bovine growth hormone on production parameters and biokinetics of key metabolites in lactating cows at peak and mid-lactation. Australian Journal of Biological Science 40, 191–202.CrossRefGoogle ScholarPubMed
McGuffey, R. K., Green, H. B. & Basson, R. P. (1990). Lactation response of dairy cows receiving bovine somatotropin and fed rations varying in crude protein and undegradable intake protein. Journal of Dairy Science 73, 2431–2443.CrossRefGoogle ScholarPubMed
National Research Council (1985). Ruminant Nitrogen Usage. Washinton, DC: National Academy Press.Google Scholar
National Research Council (1989). Nutrient Requirements of Dairy Cattle, 6th revised ed. Washington, DC: National Academy Press.Google Scholar
Ng-Kwai-Hang, K. F. & Kroeker, E. M. (1984). Rapid separation and quantification of major casein and whey proteins of bovine milk by polyacrylamide gel electrophoresis. Journal of Dairy Science 67, 3052–3056.CrossRefGoogle Scholar
Peel, C. J. & Bauman, D. E. (1987). Somatotropin and lactation. Journal of Dairy Science 70, 474–486.CrossRefGoogle ScholarPubMed
Peel, C. J., Bauman, D. E., Gorewit, R. C. & Sniffen, C. J. (1981). Effect of exogenous growth hormone on lactational performance in high yielding dairy cows. Journal of Nutrition 111, 1662–1671.CrossRefGoogle ScholarPubMed
Peel, C. J., Fronk, T. J., Bauman, D. E. & Gorewit, R. C. (1982). Lactational response to exogenous growth hormone and abomasal infusion of a glucose-sodium caseinate mixture in high yielding dairy cows. Journal of Nutrition 112, 1770–1778.CrossRefGoogle ScholarPubMed
Pocius, P. A. & Herbein, J. H. (1986). Effects of in vivo administration of growth hormone on milk production and in vitro hepatic metabolism in dairy cattle. Journal of Dairy Science 69, 713–720.CrossRefGoogle ScholarPubMed
Robertson, J. B. & Van Soest, P. J. (1981). The detergent system of analysis and its application to human foods. In The Analysis of Dietary Fiber in Food, pp. 123–155 [James, W. P. and Theander, O., editors]. New York: Marcel Dekker Inc.Google Scholar
SAS Institute Inc. (1985). SAS User's Guide: Statistics. Cary, North Carolina: SAS Institute Inc.Google Scholar
Schingoethe, D. J., Casper, D. P., Yang, C., Illg, D. J., Sommerfeldt, J. L. & Mueller, C. R. (1988). Lactational responses to soybean meal, heated soybean meal, and extruded soybeans with ruminally protected methionine. Journal of Dairy Science 71, 173–180.CrossRefGoogle ScholarPubMed
Schwab, C. G. (1989). Amino acids in dairy cow nutrition. Rhone-Poulenc Technical Symposium, pp. 75–101. Fresno: California Nutrition Conference.Google Scholar
Schwab, C. G., Satter, L. D. & Clay, A. B. (1976). Response of lactating cows to abomasal infusion of amino acids. Journal of Dairy Science 59, 1254–1270.CrossRefGoogle ScholarPubMed
Tyrrell, H. F., Brown, A. C. G., Reynolds, P. J., Haaland, G. L., Bauman, D. E., Peel, C. J. & Steinhour, W. D. (1988). Effect of bovine somatotropin on metabolism of lactating dairy cows: energy and nitrogen utilization as determined by respiration calorimetry. Journal of Nutrition 118, 1024–1030.CrossRefGoogle ScholarPubMed
Varga, G. A., Hoover, W. H., Junkins, L. L. & Shriver, B. J. (1988). Effects of urea and isoacids on in-vitro fermentation of diets containing formaldehyde-treated or untreated soybean meal. Journal of Dairy Science 71, 737–744.CrossRefGoogle Scholar
Wanderley, R. C., Al Dehneh, A., Huber, J. T., Theurer, C. B., & Teixeira, J. C. (1988). Duodenal amino acid supply in dairy cows. Journal of Animal Science 66, Suppl. 1, 484.Google Scholar
Winsryg, M. D., Arambel, M. J. & Walters, J. L. (1991). The effect of protein degradability on milk composition and production of early lactation, somatotropin-injected cows. Journal of Dairy Science 73, 2437–2443.Google Scholar
Zinn, R. A. & Owens, F. N. (1986). A rapid procedure for purine measurement and its use for estimating net ruminal protein synthesis. Canadian Journal of Animal Science 66, 157–166.CrossRefGoogle Scholar