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Effect of protein nutrition on the mRNA content of insulin-like growth factor-binding protein-1 in liver and kidney of rats

Published online by Cambridge University Press:  09 March 2007

Asako Takenaka ,
Mitsuko Hirosawa ,
Masamichi Mori ,
Sanae Yamada ,
Yutaka Miura ,
Hisanori Kato ,
Shin-Ichiro Takahashi  and
Tadashi Noguchi
Asako Takenaka
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Mitsuko Hirosawa
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Masamichi Mori
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Sanae Yamada
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Yutaka Miura
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Hisanori Kato
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Shin-Ichiro Takahashi
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Tadashi Noguchi
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
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Abstract

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Effect of quantity and nutritional quality of dietary proteins on the content of mRNA of insulin-like growth factor-binding protein-1 (IGFBP-1) was studied in rat liver and kidney. IGFBP-1 mRNA content per unit RNA increased in liver and kidney of rats fed on a protein-free diet and in those of fasted rats compared with that in the rats fed on a casein diet. When rats were given a gluten diet for 7 d, IGFBP-1 mRNA content in liver did not change significantly but that in kidney increased considerably compared with that in those organs of the rats fed on the casein diet. Because IGFBP-1 mRNA has been demonstrated both in liver parenchymal and non-parenchymal cells (Takenaka et al. 1991), the effect of the protein-free diet on these two types of cells has been studied. An increase in IGFBP-1 mRNA content under protein deprivation was observed in both liver parenchymal and non-parenchymal cells, suggesting that these two types of cells are regulated in a similar mode as far as IGFBP-1 mRNA content is concerned. The physiological and nutritional significance of the previously stated results on protein anabolism are discussed when considered together with our previous observations on the plasma concentrations of IGF-1 (Takahashi et al. 1990) and IGFBP (Umezawa et al. 1991) and insulin-like growth factor-1 mRNA content in liver (Miura et al. 1991).

Keywords

Insulin-like growth factor-1Dietary proteinProtein deficiencyIGF-binding protein-1 mRNARat
Type
Metabolic Effects of Nutrient Intakes
Information
British Journal of Nutrition , Volume 69 , Issue 1 , January 1993 , pp. 73 - 82
Copyright
Copyright © The Nutrition Society 1993

References

REFERENCES

American Institute of Nutrition (1977). Report of the AIN Ad Hoc Committee on Standards for Nutritional Studies. Journal of Nutrition 107, 1340–1348.CrossRefGoogle Scholar
Baxter, R. C. (1988). The insulin-like growth factors and their binding proteins. Comparative Biochemistry and Physiology 91B, 229–235.Google Scholar
Baxter, R. C. (1991). Physiological roles of IGF binding proteins. In Modern Concepts of Insulin-Like Growrh Factors, pp. 371–380 [Spencer, E. M. editor]. New York, Amsterdam, London, Tokyo: Elsevier.Google Scholar
Baxter, R. C. & Cowell, C. T. (1987). Diurnal rhythm of growth hormone-independent binding protein for insulin-like growth factors in human plasma. Journal of Clinical Endocrinology and Metabolism 65, 432–440.CrossRefGoogle ScholarPubMed
Baxter, R. C. & Martin, J. L. (1989). Binding proteins for the insulin-like growth factors: structure, regulation and function. Progress in Growth Factor Research 1, 49–68.CrossRefGoogle Scholar
Busby, W. H., Hossenlopp, P., Binoux, M. & Clemmons, D. R. (1989). Purified preparations of the amniotic fluid-derived insulin-like growth factor-binding protein contain multimeric forms that are biologically active. Endocrinology 125, 773–777.CrossRefGoogle ScholarPubMed
Busby, W. H., Snyder, D. K. & Clemmons, D. R. (1988). Radioimmunoassay of a 26,000-dalton plasma insulin-like growth factor-binding protein: control by nutritional variables. Journal of Clinical Endocrinology and Metabolism 67, 1225–1230.CrossRefGoogle ScholarPubMed
Clemmons, D. R. & Underwood, L. E. (1991). Nutritional regulation of IGF-I and IGF binding proteins. Annual Review of Nutrition 11, 393–412.CrossRefGoogle ScholarPubMed
Cotterill, A. M., Cowell, C. T., Baxter, R. C., McNeil, D. & Silinik, M. (1988). Regulation of the growth hormone-independent growth-factor-binding protein in children. Journal of Clinical Endocrinology and Metabolism 67, 882–887.CrossRefGoogle ScholarPubMed
Daughaday, W. H., Mariz, I. K. & Blethen, S. L. (1980). Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol-extracted serum. Journal of Clinical Endocrinology and Metabolism 51, 781–788.CrossRefGoogle Scholar
DeMellow, J. S. M. & Baxter, R. C. (1988). Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts. Biochemical and Biophysical Research Communications 156, 199–204.CrossRefGoogle Scholar
Elgin, R. G., Busby, W. H. Jr & Clemmons, D. R. (1987). An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I. Proceedings of the National Academy of sciences, USA 84, 3254–3258.CrossRefGoogle ScholarPubMed
Kaufmann, U., Zapf, J. & Froesch, E. R. (1978). Growth hormone dependence of non-suppressible insulin-like activity (NSILA) and of NSILA-carrier protein in rats. Acta Endocrinologica 87, 716–727.Google ScholarPubMed
Knauer, D. J. & Smith, G. L. (1980). Inhibition of biological activity of multiplication-stimulating activity by binding to its carrier protein. Proceedings of the National Academy of Sciences, USA 77, 7252–7256.CrossRefGoogle ScholarPubMed
Miura, Y., Kato, H. & Noguchi, T. (1992). Effect of dietary proteins on insulin-like growth Factor-1 (IGF-1) messenger ribonucleic acid content in rat liver. British Journal of Nutrition 67, 257–265.CrossRefGoogle ScholarPubMed
Murphy, L. J., Seneviratne, C., Ballejot, G., Croze, F. & Kennedy, T. G. (1990). Identification and characterization of a rat decidual insulin-like growth factor-binding protein complementary DNA. Molecular Endocrinology 4, 329–336.CrossRefGoogle ScholarPubMed
Murphy, L. J., Seneviratne, C., Moreira, P. & Reid, R. E. (1991). Enhanced expression of insulin-like growth factor-binding protein-1 in the fasted rat: the effects of insulin and growth hormone administration. Endocrinology 128, 689–696.CrossRefGoogle ScholarPubMed
Ooi, G. T., Orlowski, C. C., Brown, A. L., Becker, R. E., Unterman, T. G. & Rechler, M. M. (1990). Different tissue distribution and hormonal regulation of messenger RNAs encoding rat insulin-like growth factor-binding proteins-I and -2. Molecular Endocrinology 4, 321–328.CrossRefGoogle Scholar
Puissant, C. & Houdebine, L.-M. (1990). An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Bio Techniques 8, 148–149.Google ScholarPubMed
Ritvos, O., Ranta, T., Jalkanen, J., Suikkari, A. M., Voutilainen, R., Bohn, H. & Rutanen, E. M. (1988). Insulin-like growth factor (IGF) binding protein from human decidua inhibits the binding and biological action of IGF-I in cultured choriocarcinoma cells. Endocrinology 122, 2150–2157.CrossRefGoogle ScholarPubMed
Rosen, K. M., Lamperti, E. D. & Villa-Komaroff, L. (1990). Optimizing the Northern blot procedure. Bio Techniques 8, 398–403.Google ScholarPubMed
Sakuma, K., Ohyaman, T., Sogawa, K., Fujii-Kuriyama, Y. & Matsumura, Y. (1987). Low protein-high energy diet induces repressed transcription of albumin mRNA in rat liver. Journal of Nutrition 117, 1141–1148.CrossRefGoogle ScholarPubMed
Snedecor, G. W. & Cochran, W. G. (1967). One-way classifications. Analysis of variance. Inspection of all differences between pairs of means. In Statistical Methods, 6th ed., pp. 271–273. Ames, Iowa: Iowa State University Press.Google Scholar
Straus, D. S. & Takemoto, C. D. (1990). Effect of dietary protein deprivation on insulin-like growth factor (1GF)-I and -11, IGF binding protein-2, and serum albumin gene expression in rat. Endocrinology 127, 1849–1860.CrossRefGoogle Scholar
Takahashi, S., Kajikawa, M., Umezawa, T., Takahashi, S.-I., Kato, H., Miura, Y., Nam, T. J., Noguchi, T. & Naito, H. (1990). Effect of dietary proteins on the plasma immunoreactive insulin-like growth factor-1 /somatomedin C concentration in the rat. British Journal of Nutrition 63, 521–534.CrossRefGoogle ScholarPubMed
Takenaka, A., Miura, Y., Mori, M., Hirosawa, M., Kato, H. & Noguchi, T. (1991). Distribution of messenger RNAs of insulin-like growth factor (1GF)-binding proteins-1 and -3 between parenchymal and nonparenchymal cells in rat liver. Agricultural and Biological Chemistry 55, 1191–1193.Google Scholar
Takenaka, A., Ohishi, Y., Noguchi, T. & Naito, H. (1989). Effect of some essential amino acid deficiency in the medium on the action of insulin on primary cultured hepatocytes of rats. Hepatocytes do not respond to insulin in some essential amino acid-deficient medium. International Journal of Biochemistry 21, 1255–1263.Google Scholar
Umezawa, T., Ohsawa, Y., Miura, Y., Kato, H. & Noguchi, T. (1991). Effect of protein deprivation on insulin-like growth factor-binding proteins in rats. British Journal of Nutririon 66, 105–116.CrossRefGoogle ScholarPubMed
Waterlow, J. C., Garlick, P. J. & Millward, D. J. (1978). The effects of nutrition and hormones on protein turnover in the liver. In Protein Turnover in Mammalian Tissues and in the Whole Body, pp. 718–723. Amsterdam, New York, Oxford: North-Holland.Google Scholar